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h1152 dihydrochloride

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  • Inhibitors & Agonists
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H-1152 dihydrochloride
H-1152 dihydrochloride, H-1152 2HCl
T35328871543-07-6In house
H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 values of 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.
  • $58
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H-1152
H1152, H 1152
T7552451462-58-1
H-1152 is a cell membrane-permeable and selective ROCK (Rho-kinase) inhibitor (Ki=1.6 nM) that increases neurite length in neuron-rich cultures and inhibits MARCKS Ser159 phosphorylation in LPA-stimulated neuronal cells.
  • $43
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