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By Target- Apoptosis
- PLK(1)
- PROTACs(1)
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Results for "
granta-519
" in TargetMol Product Catalog- Inhibitors & Agonists3
- PROTAC Products1
Volasertib
Cited
BI 6727
T6019755038-65-4
Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis. It also inhibits PLK2 PLK3 (IC50s: 5 56 nM).
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CitedPROTAC TBL1X degrader-1
T201221
PROTAC TBL1X degrader-1 (Compound TD11) is a PROTAC degrader that targets and degrades the Transducin β-like protein 1 X-linked (TBL1X) protein. It exhibits cytotoxicity in lymphoma cell lines Riva, Pfeiffer, and Granta-519, with IC50 values of 0.795, 0.397, and 0.522 μM, respectively.
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Antitumor agent-23
T398892355185-12-3
Antitumor agent-23 exhibits potent antitumoral activity, as demonstrated by its GI50 values of 38, 48, 5, 27, 80, and 28 nM against the lymphoma cell lines GRANTA-519, KARPAS-422, KARPAS-299, RAMOS, DAUDI, and RAJI respectively.
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