g-150

G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).

Cross-linked dextran G 150 is a hydrophilic gel used as a gel filtration medium, with a particle size range of 40-120 μm and suitable for separating spherical proteins within a molecular weight range of 5k-300k Da.

PPO-IN-18 (Compound g13) is an inhibitor of protoporphyrinogen oxidase (PPO) and effectively inhibits Echinochloa crus-galli PPO (EcPPO) with an IC50 of 0.109 μM. It demonstrates herbicidal activity against E. crus-galli, Digitaria sanguinalis, Setaria faberi, Ipomoea nil, Chenopodium quinoa, and Abutilon theophrasti, with no significant crop toxicity at application rates of 150-300 g ai/ha.

NtPPO-IN-1 (Compound A4) is an inhibitor of Nicotiana tabacum PPO (NtPPO) with a Ki of 9.05 nM. It exhibits herbicidal activity against Setaria viridis, Echinochloa crus-galli, Digitaria sanguinalis, Amaranthus retroflexus, Abutilon theophrasti, and Portulaca oleracea, causing 30-50% damage to corn and rice at 150 g a.i./ha.

PPO-IN-11 (Compound 10bh) is an inhibitor of protoporphyrinogen IX oxidase (PPO) and specifically inhibits tobacco PPO (NtPPO) with a Ki of 0.0603 μM. It exhibits herbicidal activity against dicotyledonous weeds such as Leaf mustard, Chickweed, and Chenopodium serotinum, as well as monocotyledonous weeds like Alopecurus aequalis, Poa annua, and Polypogon fugax at a dosage of 150 g a.i./ha.

Urotensin II is a peptide vasoconstrictor and agonist of the urotensin (UT) receptor (Ki= 2.06 nM for the human recombinant receptor expressed in HEK293 cells).1It stimulates intracellular calcium mobilization in HEK293 cells expressing human and rat UT (EC50s = 0.47 and 0.78 nM, respectively) but decreases intracellular calcium concentration in goby (G. mirabilis) enterocytes when used at a concentration of 500 nM.2Urotensin II (20 mU/ml) stimulates active sodium and chloride absorption across isolated goby posterior intestine in 5% seawater-adapted solution.3In vivo, urotensin II (1.5-150 nmol/kg) decreases diastolic blood pressure and increases heart rate in anesthetized rats.4It also reduces the pressor responses to sympathetic nerve stimulation, norepinephrine , and vasopressin in pithed rats when administered at a dose of 150 nmol/kg. 1.Ames, R.S., Sarau, H.M., Chambers, J.K., et al.Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14Nature401(6750)282-286(1999) 2.Loretz, C.A., and Assad, J.A.Urotensin II lowers cytoplasmic free calcium concentration in goby enterocytes: Measurements using quin2Gen. Comp. Endocrinol.64(3)355-361(1986) 3.Loretz, C.A., Freel, R.W., and Bern, H.A.Specificity of response of intestinal ion transport systems to a pair of natural peptide hormone analogs: Somatostatin and urotensin IIGen. Comp. Endocrinol.52(2)198-206(1983) 4.Gibson, A., Wallace, P., and Bern, H.A.Cardiovascular effects of urotensin II in anesthetized and pithed ratsGen. Comp. Endocrinol.64(3)435-439(1986)

Sepimostat dimethanesulfonate (FUT-187), a chemical compound, demonstrates neuroprotective properties by antagonizing NR2B N-methyl-D-aspartate receptors at the NR2B subunit's Ifenprodil-binding site. This compound effectively inhibits Ifenprodil binding, exhibiting a Ki value of 27.7 μM[1].

BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 impurity (10 μM) induces a 150% increase in luciferase activity in a GP-BAR1 reporter gene assay

Anti-CSF3R/G-CSFR Antibody is a humanized antibody produced in CHO cells, targeting CSF3R/G-CSFR. It features a huIgG4SP heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. For an isotype control, refer to HumanIgG4kappa, Isotype Control.