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By Target- Glucagon Receptor
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Results for "
exendin (539)
" in TargetMol Product Catalog.- Inhibitors & Agonists1
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Exendin (5-39)
T39384196109-27-0
Exendin (5-39) is a potent antagonist of the glucagon-like peptide 1 (GLP-1) receptor that can ameliorate memory impairment in rats treated with β-amyloid protein.
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Exendin-3 (9-39) amide, Exendin (9-39)
TP2100133514-43-9
Avexitide (Exendin-3(9-39)amide) is a specific, competitive GLP-1 receptor antagonist (Ki = 0.36 nM). Avexitide binds to the GLP-1 receptor (GLP-1R) with high affinity (Kd = 0.42 nM), blocking the interaction between endogenous GLP-1 and the receptor, thereby counteracting the effects of excessive GLP-1 secretion. Avexitide is being studied for post-bariatric hypoglycemia (PBH) and congenital hyperinsulinism.
- $135
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