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ecopipam

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  • Inhibitors & Agonists
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Ecopipam
UNII-0X748O646K, Sch-39166, Sch 39166
T31602112108-01-7
Ecopipam (UNII-0X748O646K) is a potent, selective, and orally active antagonist of dopamine D1 D5 receptors, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam demonstrates more than 40-fold selectivity over D2, D4, 5-HT, and α2a receptors (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively). It is used in research on schizophrenia and obesity.
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6-8 weeks
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Ecopipam hydrobromide
T737092587360-22-1
Ecopipam (SCH 39166) hydrobromide is a highly potent, specific, and orally active dopamine D1 D5 receptor antagonist with K i values of 1.2 nM for D1 and 2.0 nM for D5 receptors. It shows over 40-fold greater selectivity for D1 D5 over D2, D4, 5-HT, and α2a receptors, with K i values of 0.98, 5.52, 0.08, and 0.73 μM, respectively, and is relevant for schizophrenia and obesity research.
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