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Search Result

Search Results for " domain "

Targets

Epigenetic Reader Domain Discoidin Domain Receptor (DDR) Others

713

Compounds

12

Natural Products

2633

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
TP1699L SEB Domain 144-153 acetate(210229-94-0 free base) Others
This peptide is Staphylococcal Enterotoxin B domain amino acid residue 163-172. It has been shown to inhibit transcytosis of multiple staphylococcal enterotoxins, SEA, SEE, and TSST-1.
TP1699 SEB Domain (144-153) SEB Domain 144-153
This peptide is Staphylococcal Enterotoxin B domain amino acid residue 163-172. It has been shown to inhibit transcytosis of multiple staphylococcal enterotoxins, SEA, SEE, and TSST-1.
T36656 Anti-Spike-RBD Single Domain mAb
The Anti-Spike-RBD Single Domain mAb is a monoclonal antibody derived from CHO cells in Alpaca. It is composed of VHH-huFc and exhibits a strong affinity for the SARS-CoV-2 RBD. [1]
TP2208 PDZ1 Domain inhibitor peptide Others
Novel cyclic peptide that disrupts interaction between GluR6 and PSD-95
T40409 Tau Peptide (275-305) (Repeat 2 domain)
Tau Peptide (275-305), also known as the R2 domain fragment, represents the second repeat unit of the microtubule-binding domain of the Alzheimer's tau peptide. Tau Peptide (275-305) is considered crucial in determining ...
TP2163 SEB Domain 144-153 TFA(210229-94-0 free base) SEB Domain (144-153) (TFA) Others
SEB Domain 144-153 TFA is Staphylococcal Enterotoxin B domain amino acid residue 144-153. It inhibits transcytosis of multiple staphylococcal enterotoxins, SEE, SEA, and TSST-1.
T82261 Grb2 SH2 domain inhibitor 1
Grb2 SH2 Domain Inhibitor 1 is a cyclic cell-penetrating peptide (CPP) featuring a conformationally restricted d-pro-l-pro motif ring (AF Φ Rpprrfq), where Φ represents L-naphthylalanine, R denotes D-arginine, and P indi...
T75838 PDZ1 Domain inhibitor peptide TFA
PDZ1 Domain Inhibitor Peptide TFA, a cyclic peptide featuring a β-Ala lactam side chain linker, specifically targets the PDZ1 domains of postsynaptic density protein 95 (PSD-95). It effectively disrupts the GluR6/PSD-95 ...
T77994 Grb2 SH2 domain inhibitor 1 TFA
Grb2 SH2 Domain Inhibitor 1 TFA is a cyclic cell-penetrating peptide (CPP) featuring a conformationally restricted d-pro-l-pro motif ring (AF Φ Rpprrfq), where Φ represents L-naphthylalanine, R signifies D-arginine, and ...
T2072 BET bromodomain inhibitor Epigenetic Reader Domain
BET bromodomain inhibitor is a potent BET inhibitor.
T80521 Caveolin-1 (82-101) amide (human, mouse, rat) Caveolin-1 scaffolding domain peptide c-Met/HGFR
Caveolin-1 (82-101) amide (human, mouse, rat), also known as Caveolin-1 scaffolding domain peptide, mitigates aging-related detrimental alterations in various organs and inhibits tyrosine kinases [1].
T15424 GSK1379725A Epigenetic Reader Domain
GSK1379725A is a selective BPTF ligand (Kd: 2.8 uM). It also shows no binding activity for Brd4.
T11925 M‑89 Epigenetic Reader Domain , Histone Methyltransferase
M-89, a highly potent and specific inhibitor of the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction, exhibits a Kd of 1.4 nM for menin binding. This compound holds potential for treating MLL leukemia...
T5440 Dbet57 Epigenetic Reader Domain
dBET57 is heterobifunctional degrader of BRD4 based on the PROTAC technology, exhibits significant degradation of BRD4BD1 with a DC50/5h of 500 nM ,and inactive on BRD4BD2
T4495 DBET1 Epigenetic Reader Domain
dBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apoptosis.
T5130 DBET6 Apoptosis , Epigenetic Reader Domain
dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.
T19935 XD14 Epigenetic Reader Domain
XD14 is an inhibitor of BET bromodomain (Kd of 160 nM, 170 nM, 380 nM, 490 nM, 830 nM and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively).
T3973 PF-CBP1 Epigenetic Reader Domain
PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP). It inhibits CREBBP (IC50: 125 nM) and p300 bromodomains (IC50: 363 nM).
T14685 BMS-986158 Epigenetic Reader Domain
BMS-986158 is a highly effective BET inhibitor, demonstrating IC50 values of 6.6 nM in NCI-H211 small cell lung cancer (SCLC) cells and 5 nM in MDA-MB231 triple negative breast cancer (TNBC) cells.
T9339 Stafia-1 STAT
Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.
T13363 Y06137 Epigenetic Reader Domain , PKC
Y06137 is an effective and selective BET inhibitor with a Kd of 81 nM for BRD4(1) bromodomain. Y06137 can be used for research on the treatment of castration-resistant prostate cancer.
T9109 SSAA09E2 RAAS , SARS-CoV
SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2 (ACE2).
T3311 GSK6853 Epigenetic Reader Domain
GSK6853 is a potent, soluble, cell-active, and highly selective inhibitor of the BRPF1 bromodomain.
TQ0058 MI-463 Epigenetic Reader Domain , Histone Methyltransferase
MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).
T16072 MI-538 Epigenetic Reader Domain , Histone Methyltransferase
MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).
T5362 Y06036 Epigenetic Reader Domain
Y06036, a potent and selective BET inhibitor, can bind to the BRD4(1) bromodomain (Kd: 82 nM).
T1854 MS436 Epigenetic Reader Domain
MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.
T6783 BI-7273 Epigenetic Reader Domain
BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.
TQ0083 NI-57 Epigenetic Reader Domain
NI-57 is an inhibitor of proteins of bromodomain and plant homeodomain finger-containing (BRPF) family, with IC50s of 3.1, 46 and 140 nM for BRPF1, BRPF2 (BRD1) and BRPF3, respectively.
TQ0253 PLX51107 Epigenetic Reader Domain
PLX51107 is a potent and selective BET inhibitor (Kds: 1.6, 2.1, 1.7, and 5 nM for BRD2-BD1, BRD3-BD1, BRD4-BD1, and BRDT-BD1).
T12112 MS402 Epigenetic Reader Domain
MS402 is a novel BD1-selective BET BrD inhibitor.
TQ0069 MI-503 Epigenetic Reader Domain , Histone Methyltransferase
MI-503 is a highly effective and orally bioavailable inhibitor of the menin-mLL interaction.
T16321 NI-42 Epigenetic Reader Domain
NI-42 is a structurally orthogonal chemical probe for the BRPFs and is biased. It effective inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM). It also has excellent sele...
T9749 FHD-286 Epigenetic Reader Domain
FHD-286 is an inhibitor of BRM/BRG1 ATPase and can be used for studies on the treatment of BAF-related disorders such as acute myeloid leukemia.
T2127 OF-1 Epigenetic Reader Domain
OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.
T5442 A1874 Epigenetic Reader Domain , PROTACs
A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. Effective in inhibiting many cancer cell lines proliferation.
T5435 ARV-771 Epigenetic Reader Domain
ARV-771 is a potent BET degrader based on PROTAC technology with Kds of 34, 4.7, 8.3, 7.6, 9.6, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively[1].
T17697 BRD7-IN-1 Epigenetic Reader Domain
BRD7-IN-1, a modified derivative of BI7273 (BRD7/9 inhibitor), forms PROTAC VZ185 through linkage to a VHL ligand, demonstrating potent activity against BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively [1].
T11136 E-7386 E7386 Epigenetic Reader Domain
E-7386 is an oral active CBP/ -catenin modulator.
T17311 (+)-JQ1 PA Epigenetic Reader Domain
(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).
T9568 SGC-SMARCA-BRDVIII Epigenetic Reader Domain
SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM, respectively.
T5417 INCB-057643 Apoptosis , Epigenetic Reader Domain
INCB057643 is a potent, selective and orally bioavailable BET inhibitor.
T5434 ARV-825 Epigenetic Reader Domain
ARV-825, a heterobifunctional PROTAC (Proteolysis Targeting Chimera) that recruits BRD4 to the E3 ubiquitin ligase cereblon leading to fast, efficient, and prolonged degradation of BRD4 in all BL cell lines tested.
T3337 Ddr1-In-1 Discoidin Domain Receptor (DDR)
DDR1-IN-1 is an effective and specific DDR1 receptor tyrosine kinase inhibitor (IC50: 105 nM), about 3-fold selectivity over DDR2.
T9063 Clathrin-IN-1 HIV Protease
Clathrin-IN-1 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research.
T3624 A-366 A 366,A366 Epigenetic Reader Domain , Histone Methyltransferase
A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.It is more than 1,000-fold selective for G9a and GLP over the other 21 met...
T6939 PFI-3 PFI 3 Epigenetic Reader Domain
PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.
T6859 I-BRD9 GSK602 Epigenetic Reader Domain
I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.
T6786 BI-9564 BI 9564,BI9564 Epigenetic Reader Domain
BI-9564, a specific cell-permeable BRD9 BD inhibitor. The Kd for BRD9 is 5.9 nM, and IC50 for BET family is > 100 μM.
T9703 GSK778 Epigenetic Reader Domain
GSK778 is a potent and selective inhibitor of BD1 bromodomain such as BRD2 BD1 (IC50s = 75 nM), BRD3 BD1 (IC50s = 41 nM), BRD4 BD1 (IC50s = 41 nM), and BRDT BD1 (IC50s = 143 nM). GSK778 inhibits proliferation, induces a ...

Compounds

SEB Domain 144-153 acetate(210229-94-0 free base)
TP1699L
Synonym:
Target: Others
SEB Domain (144-153)
TP1699
Synonym: SEB Domain 144-153
Target:
Anti-Spike-RBD Single Domain mAb
T36656
Synonym:
Target:
PDZ1 Domain inhibitor peptide
TP2208
Synonym:
Target: Others
Tau Peptide (275-305) (Repeat 2 domain)
T40409
Synonym:
Target:
SEB Domain 144-153 TFA(210229-94-0 free base)
TP2163
Synonym: SEB Domain (144-153) (TFA)
Target: Others
Grb2 SH2 domain inhibitor 1
T82261
Synonym:
Target:
PDZ1 Domain inhibitor peptide TFA
T75838
Synonym:
Target:
Grb2 SH2 domain inhibitor 1 TFA
T77994
Synonym:
Target:
BET bromodomain inhibitor
T2072
Synonym:
Target: Epigenetic Reader Domain
Caveolin-1 (82-101) amide (human, mouse, rat)
T80521
Synonym: Caveolin-1 scaffolding domain peptide
Target: c-Met/HGFR
GSK1379725A
T15424
Synonym:
Target: Epigenetic Reader Domain
M‑89
T11925
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
Dbet57
T5440
Synonym:
Target: Epigenetic Reader Domain
dBET1
T4495
Synonym:
Target: Epigenetic Reader Domain
dBET6
T5130
Synonym:
Target: Apoptosis, Epigenetic Reader Domain
XD14
T19935
Synonym:
Target: Epigenetic Reader Domain
PF-CBP1
T3973
Synonym:
Target: Epigenetic Reader Domain
BMS-986158
T14685
Synonym:
Target: Epigenetic Reader Domain
Stafia-1
T9339
Synonym:
Target: STAT
Y06137
T13363
Synonym:
Target: Epigenetic Reader Domain, PKC
SSAA09E2
T9109
Synonym:
Target: RAAS, SARS-CoV
GSK6853
T3311
Synonym:
Target: Epigenetic Reader Domain
MI-463
TQ0058
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
MI-538
T16072
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
Y06036
T5362
Synonym:
Target: Epigenetic Reader Domain
MS436
T1854
Synonym:
Target: Epigenetic Reader Domain
BI-7273
T6783
Synonym:
Target: Epigenetic Reader Domain
NI-57
TQ0083
Synonym:
Target: Epigenetic Reader Domain
PLX51107
TQ0253
Synonym:
Target: Epigenetic Reader Domain
MS402
T12112
Synonym:
Target: Epigenetic Reader Domain
MI-503
TQ0069
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
NI-42
T16321
Synonym:
Target: Epigenetic Reader Domain
FHD-286
T9749
Synonym:
Target: Epigenetic Reader Domain
OF-1
T2127
Synonym:
Target: Epigenetic Reader Domain
A1874
T5442
Synonym:
Target: Epigenetic Reader Domain, PROTACs
ARV-771
T5435
Synonym:
Target: Epigenetic Reader Domain
BRD7-IN-1
T17697
Synonym:
Target: Epigenetic Reader Domain
E-7386
T11136
Synonym: E7386
Target: Epigenetic Reader Domain
(+)-JQ1 PA
T17311
Synonym:
Target: Epigenetic Reader Domain
SGC-SMARCA-BRDVIII
T9568
Synonym:
Target: Epigenetic Reader Domain
INCB-057643
T5417
Synonym:
Target: Apoptosis, Epigenetic Reader Domain
ARV-825
T5434
Synonym:
Target: Epigenetic Reader Domain
Ddr1-In-1
T3337
Synonym:
Target: Discoidin Domain Receptor (DDR)
Clathrin-IN-1
T9063
Synonym:
Target: HIV Protease
A-366
T3624
Synonym: A 366,A366
Target: Epigenetic Reader Domain, Histone Methyltransferase
PFI-3
T6939
Synonym: PFI 3
Target: Epigenetic Reader Domain
I-BRD9
T6859
Synonym: GSK602
Target: Epigenetic Reader Domain
BI-9564
T6786
Synonym: BI 9564,BI9564
Target: Epigenetic Reader Domain
GSK778
T9703
Synonym:
Target: Epigenetic Reader Domain
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Cat No. Product Name Synonyms Targets
TN2269 Tetramethylcurcumin Apoptosis , STAT
Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and e...
T6389 Anacardic Acid 6-pentadecylsalicylic Acid,Hydroginkgolic acid Others , Epigenetic Reader Domain , Histone Acetyltransferase , Antibacterial
Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity, antibacterial activity, and inhibits prostagland...
T1516 Curcumin Diferuloylmethane,Natural Yellow 3,Indian Saffron,Turmeric yellow Mitophagy , Epigenetic Reader Domain , Ferroptosis , Influenza Virus , Nrf2 , Histone Acetyltransferase , HDAC , Autophagy
Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity. Curcumin has a wide range of pharmacological activities such as antitumor, ant...
T3862 Irigenin NF-κB , Integrin
Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enha...
TN2285 DL-Tryptophan (±)-Tryptophan,Tryptophan Serotonin Transporter , Endogenous Metabolite
DL-Tryptophan ((±)-Tryptophan) containing dipeptides are interesting ingredients for functional foods as a natural prevention for hypertension with reduced side effects due to its selective inhibition of the C-domain. Lo...
T2730 Gossypol (acetic acid) (±)-Gossypol-acetic acid,Pogosin,AT101,Gossypol acetic acid BCL
Gossypol acetic acid (AT101), a polyphenolic compound isolated from cottonseeds, binds with Bcl-2, Bcl-xL, Mcl-1, and does not inhibit BIR3 domain and BID.
T6343 Geldanamycin NSC 122750 HSP , Influenza Virus , Tyrosine Kinases , Antibacterial , Antibiotic
Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.
TL0017 Aristolactam AIIIa MAPK , CDK
Aristolactam AIIIa is a new type of Plk1 inhibitors, targeting the Polo Box domain (PBD), it has anti-tumor activity. Aristolactam IIIa shows inhibition of platelet aggregation induced by collagen or arachidonic acid.
T16719 Radicicol Monorden HSP
Radicicol is an antifungal antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is an inhibitor of Hsp90 (IC50: 1 μM). Radicicol binds to the ATPase domain of Hsp90 and pr...
T14831 Bryostatin 1 HIV Protease , PKC
Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a CNS)permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein (Kis: 8.0...
T73876 Sanggenon G
Sanggenon G, a cell-permeable and potent inhibitor of X-linked inhibitor of apoptosis protein (XIAP), specifically binds to the XIAP BIR3 domain with a binding affinity of 34.26 μM, thereby enhancing caspase activation [...
TN3616 Cedrelone Apoptosis , MMP , Antifection
Cedrelone is a citrulline analog and a phenazine biosynthesis-like domain protein (PBLD) activator.Cedrelone induces apoptosis in cancer cells.Cedrelone is a very potent inducer of apoptosis, causing cell cycle arrest.Ce...

Natural Products

Tetramethylcurcumin
TN2269
Synonym:
Target: Apoptosis, STAT
Anacardic Acid
T6389
Synonym: 6-pentadecylsalicylic Acid,Hydroginkgolic acid
Target: Others, Epigenetic Reader Domain, Histone Acetyltransferase, Antibacterial
Curcumin
T1516
Synonym: Diferuloylmethane,Natural Yellow 3,Indian Saffron,Turmeric yellow
Target: Mitophagy, Epigenetic Reader Domain, Ferroptosis, Influenza Virus, Nrf2, Histone Acetyltransferase, HDAC, Autophagy
Irigenin
T3862
Synonym:
Target: NF-κB, Integrin
DL-Tryptophan
TN2285
Synonym: (±)-Tryptophan,Tryptophan
Target: Serotonin Transporter, Endogenous Metabolite
Gossypol (acetic acid)
T2730
Synonym: (±)-Gossypol-acetic acid,Pogosin,AT101,Gossypol acetic acid
Target: BCL
Geldanamycin
T6343
Synonym: NSC 122750
Target: HSP, Influenza Virus, Tyrosine Kinases, Antibacterial, Antibiotic
Aristolactam AIIIa
TL0017
Synonym:
Target: MAPK, CDK
Radicicol
T16719
Synonym: Monorden
Target: HSP
Bryostatin 1
T14831
Synonym:
Target: HIV Protease, PKC
Sanggenon G
T73876
Synonym:
Target:
Cedrelone
TN3616
Synonym:
Target: Apoptosis, MMP, Antifection

Recombinant Proteins

Species：
Human (1336)
Mouse (421)
SARS-CoV-2 (340)
Rat (150)
Cynomolgus (111)
Rhesus (58)
Canine (26)
EBOV (22)
SARS (18)
Cynomolgus,Rhesus (12)
Expression System：
HEK293 (1667)
Human Cells (347)
E. coli (332)
Baculovirus-Insect Cells (237)
Yeast (20)
CHO (12)
Baculovirus (10)
in vitro E. coli expression system (5)
E.coli (1)
Tag：
His (955)
hFc (339)
Tag Free (237)
C-6His (199)
C-His-Avi (97)
C-Fc (83)
His,AVI (75)
His,GST (67)
C-His (50)
N-6His (48)
Cat No. Product Name Species Expression System
TMPY-02869 MMP-12 Protein, Human, Recombinant (catalytic domain) Human E. coli
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPY-03835 CDCP1 Protein, Rhesus, Recombinant (His) Rhesus HEK293
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-02882 HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) HIV HEK293
TMPY-04625 SEMA3A Protein, Mouse, Recombinant (His) Mouse HEK293
Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 5 aa Sema domain. They are best characterized in relation to axon guidance during development of the nervous sys...
TMPY-01460 ABHD4 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain...
TMPY-04796 VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) Human HEK293
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-01859 LYPD3 Protein, Human, Recombinant (His) Human HEK293
Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4, and LYPD3, is a cell membrane protein that contains two UPAR/Ly6 ...
TMPY-04802 VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc) Human HEK293
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-04794 VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc) Human HEK293
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-04795 VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His) Human HEK293
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-04298 CDCP1 Protein, Human, Recombinant (His) Human HEK293
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-06074 B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express...
TMPY-01907 VSIG4 Protein, Human, Recombinant (His) Human HEK293
VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an...
TMPY-02785 Tetranectin Protein, Mouse, Recombinant (His) Mouse HEK293
Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes v...
TMPY-00124 SEMA3A Protein, Human, Recombinant (hFc) Human HEK293
Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 5 aa Sema domain. They are best characterized in relation to axon guidance during development of the nervous sys...
TMPK-00398 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPK-00399 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPY-01882 HE4 Protein, Human, Recombinant (His) Human HEK293
WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP ...
TMPY-00586 CLEC-2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ...
TMPY-01894 SIGIRR Protein, Human, Recombinant (His) Human HEK293
Single Ig IL-1-related receptor (SIGIRR) or TIR8 is a member of Toll-like receptor-interleukin 1 receptor signaling (TLR-IL-1R) receptor superfamily. Although SIGIRR/TIR8 shows the typical conserved motifs that character...
TMPY-02361 VEGFR2/KDR Protein, Human, Recombinant (His) Human HEK293
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-05581 TIM-4/TIMD4 Protein, Human, Recombinant (His), Biotinylated Human HEK293
A type I transmembrane protein called TIM4 (T-cell immunoglobulin- and mucin-domain-containing molecule; also known as TIMD4), which belongs to the immunoglobulin superfamily and TIM family. TIM4 is involved in regulatin...
TMPK-00599 Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc) Human HEK293
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent r...
TMPY-05322 B7-H4 Protein, Mouse, Recombinant (His) Mouse HEK293
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express...
TMPY-05586 CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent i...
TMPK-00949 CDH17 Domain 7 Protein, Human, Recombinant (hFc) Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPY-05556 Adiponectin Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other t...
TMPY-02971 CLEC10A Protein, Human, Recombinant (hFc) Human HEK293
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is ...
TMPY-02848 Adiponectin Protein, Human, Recombinant (hFc) Human HEK293
Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other t...
TMPK-00950 CDH17 Domain 6-7 Protein, Human, Recombinant (hFc) Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00952 CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc) Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00953 CDH17 Domain 6-7 Protein, Human, Recombinant (mFc) Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPY-02719 NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc) Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-06076 LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) Human HEK293
LILRA2 (Leukocyte Immunoglobulin Like Receptor A2, also known as LIR7 and ILT1) is a Protein Coding gene. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentatio...
TMPK-00155 DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi) Human HEK293
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes.
TMPK-00309 Nectin-4 Protein IgV Domain, Human, Recombinant (His & Avi) Human HEK293
Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry in...
TMPY-05045 CSF1R Protein, Human, Recombinant (Domain I&II&III, His) Human HEK293
M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein...
TMPK-00156 DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi) Human HEK293
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes.
TMPY-02600 NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPK-01353 IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi) Human HEK293
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer.
TMPK-01355 IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi) Human HEK293
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer.
TMPK-00429 HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi) Human HEK293
ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for t...
TMPK-00262 SARS-COV-2 Nucleocapsid Protein NTD Domain (His & Avi) SARS-CoV-2 E. coli
Nucleocapsid protein (N) is the major viral structural component; its main function is to protect and encapsidate the viral RNA forming viral RNP complex. It is encoded by the S segment vRNA and is abundantly expressed i...
TMPK-00264 SARS-COV-2 Nucleocapsid Protein CTD Domain (His & Avi) SARS-CoV-2 E. coli
Nucleocapsid protein (N) is the major viral structural component; its main function is to protect and encapsidate the viral RNA forming viral RNP complex. It is encoded by the S segment vRNA and is abundantly expressed i...
TMPK-00157 DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes.
TMPJ-01433 Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated Human E. coli
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components ...
TMPK-00158 DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes.
TMPK-00605 LILRB4/CD85k/ILT3 Domain 1 Protein, Human, Recombinant (His & Avi) Human HEK293
LILRB4,also known as CD85k and LIR-5, ILT-3,  is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT-3 consists of a 238 amino acid (aa) extracellular dom...
TMPK-00430 HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for t...
TMPY-05071 IgE Fc Protein, Human, Recombinant (Constant Domain 3 & 4, His) Human HEK293
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MMP-12 Protein, Human, Recombinant (catalytic domain)
TMPY-02869
Species: Human
Expression System: E. coli
CDCP1 Protein, Rhesus, Recombinant (His)
TMPY-03835
Species: Rhesus
Expression System: HEK293
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His)
TMPY-02882
Species: HIV
Expression System: HEK293
SEMA3A Protein, Mouse, Recombinant (His)
TMPY-04625
Species: Mouse
Expression System: HEK293
ABHD4 Protein, Human, Recombinant (His)
TMPY-01460
Species: Human
Expression System: Baculovirus-Insect Cells
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
TMPY-04796
Species: Human
Expression System: HEK293
LYPD3 Protein, Human, Recombinant (His)
TMPY-01859
Species: Human
Expression System: HEK293
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)
TMPY-04802
Species: Human
Expression System: HEK293
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc)
TMPY-04794
Species: Human
Expression System: HEK293
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)
TMPY-04795
Species: Human
Expression System: HEK293
CDCP1 Protein, Human, Recombinant (His)
TMPY-04298
Species: Human
Expression System: HEK293
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-06074
Species: Cynomolgus,Rhesus
Expression System: HEK293
VSIG4 Protein, Human, Recombinant (His)
TMPY-01907
Species: Human
Expression System: HEK293
Tetranectin Protein, Mouse, Recombinant (His)
TMPY-02785
Species: Mouse
Expression System: HEK293
SEMA3A Protein, Human, Recombinant (hFc)
TMPY-00124
Species: Human
Expression System: HEK293
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
TMPK-00398
Species: Human
Expression System: HEK293
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
TMPK-00399
Species: Human
Expression System: HEK293
HE4 Protein, Human, Recombinant (His)
TMPY-01882
Species: Human
Expression System: HEK293
CLEC-2 Protein, Mouse, Recombinant (hFc)
TMPY-00586
Species: Mouse
Expression System: HEK293
SIGIRR Protein, Human, Recombinant (His)
TMPY-01894
Species: Human
Expression System: HEK293
VEGFR2/KDR Protein, Human, Recombinant (His)
TMPY-02361
Species: Human
Expression System: HEK293
TIM-4/TIMD4 Protein, Human, Recombinant (His), Biotinylated
TMPY-05581
Species: Human
Expression System: HEK293
Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc)
TMPK-00599
Species: Human
Expression System: HEK293
B7-H4 Protein, Mouse, Recombinant (His)
TMPY-05322
Species: Mouse
Expression System: HEK293
CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05586
Species: Human
Expression System: HEK293
CDH17 Domain 7 Protein, Human, Recombinant (hFc)
TMPK-00949
Species: Human
Expression System: HEK293
Adiponectin Protein, Human, Recombinant (His)
TMPY-05556
Species: Human
Expression System: Baculovirus-Insect Cells
CLEC10A Protein, Human, Recombinant (hFc)
TMPY-02971
Species: Human
Expression System: HEK293
Adiponectin Protein, Human, Recombinant (hFc)
TMPY-02848
Species: Human
Expression System: HEK293
CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)
TMPK-00950
Species: Human
Expression System: HEK293
CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)
TMPK-00952
Species: Human
Expression System: HEK293
CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)
TMPK-00953
Species: Human
Expression System: HEK293
NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc)
TMPY-02719
Species: Human
Expression System: HEK293
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)
TMPY-06076
Species: Human
Expression System: HEK293
DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi)
TMPK-00155
Species: Human
Expression System: HEK293
Nectin-4 Protein IgV Domain, Human, Recombinant (His & Avi)
TMPK-00309
Species: Human
Expression System: HEK293
CSF1R Protein, Human, Recombinant (Domain I&II&III, His)
TMPY-05045
Species: Human
Expression System: HEK293
DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi)
TMPK-00156
Species: Human
Expression System: HEK293
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)
TMPY-02600
Species: Human
Expression System: HEK293
IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)
TMPK-01353
Species: Human
Expression System: HEK293
IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)
TMPK-01355
Species: Human
Expression System: HEK293
HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi)
TMPK-00429
Species: Human
Expression System: HEK293
SARS-COV-2 Nucleocapsid Protein NTD Domain (His & Avi)
TMPK-00262
Species: SARS-CoV-2
Expression System: E. coli
SARS-COV-2 Nucleocapsid Protein CTD Domain (His & Avi)
TMPK-00264
Species: SARS-CoV-2
Expression System: E. coli
DKK1 C terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPK-00157
Species: Human
Expression System: HEK293
Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated
TMPJ-01433
Species: Human
Expression System: E. coli
DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPK-00158
Species: Human
Expression System: HEK293
LILRB4/CD85k/ILT3 Domain 1 Protein, Human, Recombinant (His & Avi)
TMPK-00605
Species: Human
Expression System: HEK293
HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00430
Species: Human
Expression System: HEK293
IgE Fc Protein, Human, Recombinant (Constant Domain 3 & 4, His)
TMPY-05071
Species: Human
Expression System: HEK293
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Cat No. Product Name
L8720 Pyroptosis Compound Library

1077 compounds
1077 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.
L1710 Anti-COVID-19 Compound Library

1160 compounds
A unique collection of 1160 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents；

Libraries

Pyroptosis Compound Library
L8720
Compounds: 1077
Anti-COVID-19 Compound Library
L1710
Compounds: 1160
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