89
20
65
4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1907 | Mdivi-1 | Mitochondrial division inhibitor 1 | Apoptosis , Mitophagy , Dynamin , Autophagy |
Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM). Mdivi-1 inhibits mitochondrial autophagy. | |||
T8513 | Spastazoline | Others | |
Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ). | |||
T6393 | ARQ 621 | Kinesin | |
ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1. | |||
T21970 | ML-097 | GTPase | |
ML-097 (CID-2160985) is a pan activator of Ras-related GTPases | |||
T12642L | Simurosertib | TAK-931 | CDK |
Simurosertib (TAK-931) is a selective and ATP-competitive cell division cycle 7 kinase inhibitor (IC50: <0.3 nM). | |||
T21678 | 3MB-PP1 | PLK | |
3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting Plk1. 3MB-PP1 specifi... | |||
T0849 | Pyrimethamine | Pirimecidan,RP 4753,Pirimetamin | DHFR , Antifolate , Parasite |
Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug. | |||
T22991 | ML-099 | Rho , Ras | |
pan activator of Ras-related GTPases | |||
T8586 | Cicloprofen | Others | |
cicloprofen is Cell division cycle 7-related protein kinase (human) inhibitor. | |||
T12642 | (R)-Simurosertib | (R)-TAK-931 | CDK |
(R)-Simurosertib ((R)-TAK-931) is an inhibitor of the ATP-competitive cell division cycle 7 (CDC7) kinase. | |||
T15141 | DM4 | Ravtansine | Others , Microtubule Associated |
DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division. | |||
T3256 | MMAF | MonoMethyl auristatin F | Others , Microtubule Associated |
MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin. | |||
T6897 | Monomethyl auristatin E | Vedotin,MMAE | Apoptosis , Microtubule Associated |
Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity. | |||
T3352 | XL413 | cholecystokinin , Casein Kinase , Pim , CDK | |
XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. XL-413 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA ... | |||
T14348 | Auristatin E | Microtubule Associated | |
Auristatin E inhibits cell division by blocking the polymerisation of tubulin. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjuga... | |||
T1060 | Flumequine | Flumigal,R-802 | Topoisomerase , Antibacterial , Antibiotic |
Flumequine (R-802) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, enzymes necess... | |||
T25214 | CCR-11 | CCR11,CCR 11 | Antibiotic |
CCR-11 is a tannin-containing derivative with antimicrobial activity. CCR-11 inhibits the proliferation of B. subtilis and HeLa cells. CCR-11 inhibits bacterial proliferation and bacterial cytoplasmic division by inhibit... | |||
T11929 | M2N12 | Phosphatase | |
M2N12 also has promising activity against Cdc25A and Cdc25B with IC50 values of 0.53 μM and 1.39 μM. Anti-tumor activity. M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhi... | |||
T6437 | Cefoperazone | Cefob,Medocef | Antibacterial , Antibiotic |
Cefoperazone (Medocef) binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial ce... | |||
T10735 | CDK4/6/1 Inhibitor | Crozbaciclib | CDK |
CDK4/6/1 Inhibitor (Crozbaciclib) is a type of CDK4/6 inhibitor (IC50s: 3 and 1 nM). CDK4/6 inhibitor is a class of compounds used for the treatment of some types of hormone receptor positive, HER2-negative breast cancer... | |||
T1213 | Piperacillin sodium | Sodium piperacillin,CL227193,Piperacillin sodium salt | Antibacterial , Antibiotic |
(CL227193) )binds to and inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall, resulting in the weakening of the bacterial cell wall and cell lysis. Piperacilli... | |||
T4433 | 6-CFDA N-succinimidyl ester | Carboxyfluorescein diacetate succinimidyl | Others |
6-CFDA N-succinimidyl ester (Carboxyfluorescein diacetate succinimidyl) is capable of spontaneously and irreversibly binding to free amines. Utilized in flow cytometry experiments for tracking cell division in both mamma... | |||
T2511 | Plinabulin | NPI-2358 | Microtubule Associated |
Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM). Plinabulin selectively targets and binds to the colchicine-binding site of tubulin, the... | |||
T1600 | Doxifluridine | Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by... | |||
T1408 | Capecitabine | Xeloda,Capecitibine,Capiibine,RO 09-1978 | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moie... | |||
T3661 | Citarinostat | ACY241,HDAC-IN-2 | HDAC |
ACY-241, also known as Citarinostat (ACY241), is a potent, selective and orally available histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity. Upon oral administration, ACY-241 inhibits the activ... | |||
T1228 | Cefonicid sodium | Monocid sodium,Cefonicid disodium salt | Antibacterial , Antibiotic |
Cefonicid binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Cefonicid sodium (Monocid sodium) is the sodium salt form of cefonicid, a semisynthetic seco... | |||
T1122 | Cephalothin sodium | Cefalotin sodium,Cephalothin,Cefalotin | Antibacterial , Antibiotic |
Cephalothin sodium (Cefalotin) binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cephalothin sodium (Cefalotin) is the sodium salt form of cephalothin, a... | |||
T67509 | Cholesteryl Hemisuccinate | Cholesterol hydrogen succinate | Apoptosis , DNA/RNA Synthesis , Topoisomerase |
Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties. Cholesteryl ... | |||
T3615 | Evofosfamide | TH-302 | Apoptosis , Others |
Evofosfamide (TH-302) is a hypoxia-activated prodrug of the cytotoxin bromo-isophosphoramide mustard (Br-IPM) conjugated with 2-nitroimidazole, with potential antineoplastic activity. When exposed to hypoxic conditions, ... | |||
T25529 | IMM-01 | GTPase | |
IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin filaments, and their organization with microfilaments to establ... | |||
T40443 | JAK2-IN-6 | JAK2-IN-6 | JAK |
JAK2-IN-6, a polysubstituted aminothiazole derivative, is a potent and selective inhibitor of JAK2 (ic50 at 22.86 μg/mL). Jak2-in-6 inhibits the activity of JAK2 enzymes by interfering with Jak2-related signaling pathway... | |||
T28305 | PC58538 | PC-58538,PC 58538 | |
PC58538 is an inhibitor of FtsZ protein, a important role in the division machinery of bacterial cells. | |||
T24126 | Gyramide A | Gyramide-A | |
Gyramide A is an inhibitor of bacterial DNA gyrase. It shows antimicrobial activity and inhibits bacterial cell division. | |||
T34924 | Triadimenol | Spinnaker,UK199,Baytan,UK 199,UK-199 | |
Triadimenol is a systemic fungicide with a broad spectrum. It inhibits the ergosterol - and gibberellin - biosynthesis, and thus the rate of cell division. | |||
T23578 | (S)-Gyramide A | (S)-Gyramide-A,(S)-534F6,(S)534F6,(S) 534F6 | |
(S)-Gyramide A is a bacterial DNA gyrase inhibitor that acts by exhibiting antimicrobial activity and inhibiting bacterial cell division. | |||
T19830 | Dicapthon | AC4124,AC 4124,Captex,ENT-17035,ENT 17035,AC-4124 | |
Dicapthon is an insecticide. Dicapthon increases the occurrence of abnormal cell frequency, decreases the mitotic index, and decreases the nuclear division index. | |||
T29205 | Zarilamide | Zarilamid | |
Zarilamide is inhibitor of the nuclear division in germinating zoospore cysts of Phytophthora capsici. Zarilamide destructs the microtubule cytoskeleton, resulting in a consequent inhibition of mitosis. | |||
T38428 | Alisertib sodium | MLN 8237 sodium | |
Alisertib sodium (MLN 8237) is a potent and specific inhibitor (IC50 = 1.2 nM) of Aurora A kinase, an enzyme involved in cell division. By binding to Aurora A kinase, Alisertib sodium disrupts the formation of the mitoti... | |||
T21298 | SNS-314 | SNS-314 free base,SNS314,SNS 314 | |
SNS-314, a synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity, selectively binds and inhibits AKs A and B, resulting in the inhibition of cell division and proliferation in tumor... | |||
T40782 | Metazachlor | ||
Metazachlor, a member of the chloroacetamide class of herbicides, acts as a long chain fatty acid synthesis inhibitor. It exerts an influence on cell division and tissue differentiation in germinating and emerging weed s... | |||
T31838 | Folic acid, methyl- | x-Methylfolic acid,x-Methyl folic acid,x-Methylpteroylglutamic acid | |
Folic acid, methyl- is a nutrient that belongs to the vitamin B family. Folate is significant for the easy conversion of carbohydrates into glucose and is essential in red blood cell formation, cell division, detoxificat... | |||
T36106 | Coumermycin A1 | ||
Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. Coumermycin A1-induced-JAK2 signal activation increases the mRNA level of SCOS2, but reducea... | |||
T32655 | L-Ergothionine hydrochloride | l-Ergothionine HCl | |
l-Ergothionine hydrochloride is a sulfur-containing amino acid, which is only produced by Actinomycetales bacteria and non-yeast-like fungi belonging to the division Basidiomycota and Ascomycota. It was originally isolat... | |||
T70958 | Dov-Val-Dil-OH TFA | ||
Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins are antimitotic agents which inhibits cell division by blocking the po... | |||
T40816 | Metalaxyl-M | Metalaxyl-M,(R)-Metalaxyl | |
Metalaxyl-M ((R)-Metalaxyl) is the active (R)-enantiomer of Metalaxyl. Metalaxyl-M is a broad-spectrum fungicide that inhibits protein and ribosomal RNA synthesis in fungi. Metalaxyl is used for research of plant disease... | |||
T36801 | Binucleine 2 | ||
Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-d... | |||
T25043 | Alestramustine | ||
Alestramustine is a cytostatic antineoplastic agent. The drug, via its active metabolites, binds to microtubule-associated proteins and β-tubulin and interferes with microtubule function, thereby suppressing cell divisio... | |||
T78591 | Zoxamide | RH-7281 | |
Zoxamide (RH-7281) is an oomycete-specific fungicide that impedes nuclear division in Phytophthora capsici germlings and disrupts the microtubule cytoskeleton [1] [2]. | |||
T72934 | Epothilone E | 埃博霉素E | |
Epothilone E is a related compound of epothilone, which inhibits microtubule protein function and blocks cell division, and has anti-tumor activity . |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN2190 | Scoulerine | Apoptosis , Beta-Secretase , BACE , Parasite | |
Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells. | |||
T2223 | Kinetin | 6-Furfuryladenine,N6-Furfuryladenine | Others |
Kinetin (N6-Furfuryladenine), a type of cytokinin, has plant growth regulation effects. | |||
T13818 | Phytohemagglutinin | PHA-M | Apoptosis |
Phytohemagglutinin (PHA-M) is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3. Anti-tumor activity | |||
T2982 | Xanthone | Genicide,Xanthenone,Benzophenone oxide | Apoptosis , Others , Influenza Virus , Antibacterial , Antifungal |
Xanthone (Xanthenone) is currently used as ovicide for codling moth eggs and as a larvicide. | |||
T8211 | (±)-Decursinol | 3',4'-dihydro-3'-hydroxy-Xanthyletin | Others , Antibacterial |
(±)-Decursinol (3',4'-dihydro-3'-hydroxy-Xanthyletin) is a natural product from Angelica gigas. | |||
T3151 | Brassinolide | Brassin lactone,24-Epibrassinolide | Apoptosis , Others |
Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division. | |||
T2942 | Psoralen | Ficusin,Furocoumarin,psoralene | Apoptosis , Influenza Virus , HIV Protease , DNA/RNA Synthesis |
Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division. | |||
T7132 | (Rac)-Brassinazole | BRASSINAZOLE | P450 |
(Rac)-Brassinazole are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a triazole-type brassinosteroid biosynth... | |||
T4454 | Traumatic Acid | Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,Trans-2-Dodecenedioic Acid | Antioxidant |
Traumatic Acid (Dodec-2-Enedioic Acid) is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective callus. | |||
TMS2181 | Trans-Zeatin | (E)-Zeatin | ERK , MEK , Endogenous Metabolite |
trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing. | |||
TMS2182 | Trans-Zeatinriboside | Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside | Others |
trans-Zeatinriboside (Ribosylzeatin) is the most active and ubiquitous form of the naturally occurring cytokinins that promote cell division, stimulate shoot proliferation, inhibit root formation, slow the aging process,... | |||
TMS2179 | Zeatin | 玉米 | Others |
Zeatin is a cytokinin derived from adenine. Zeatin was discovered in immature corn kernels from the genus Zea. It promotes growth of lateral buds and when sprayed on meristems stimulates cell division to produce bushier ... | |||
T1004 | 6-Benzylaminopurine | 6-BAP,N6-Benzyladenine,BA,Benzyladenine | Others |
6-Benzylaminopurine (6-BAP), benzyl adenine or BAP is a first-generation synthetic cytokinin that elicits plant growth and development responses, setting blossoms and stimulating fruit richness by stimulating cell divisi... | |||
T5088 | 3-Indoleacetic acid sodium | Indole-3-Acetic Acid sodium salt,Sodium 2-(1H-indol-3-yl)acetate,IAA sodium salt,Heteroauxin sodium salt | Others , Endogenous Metabolite |
3-Indoleacetic acid sodium (Heteroauxin sodium salt) is a naturally occurring plant hormone of the auxin class. It can stimulate cell elongation and division, promoting plant growth and development. However, at high conc... | |||
TMM2618 | Gibberllin A7 | Gibberellin A7,Gibberllin 7 | Others |
Gibberllin A7 (Gibberllin 7) is important plant growth hormones that promote plant cell growth and elongation. Gebberillins promote rapid stem and root growth, induce mitotic division and initiate (break dormancy) and in... | |||
T38141 | Glycerophospholipids, cephalins | Phosphatidylethanolamines (egg) | |
Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) are a class of phospholipid compounds. phosphatidylethanolamines (egg) are a mixture of phosphatidylethanolamines isolated from eggs with various fatty ac... | |||
T14304 | Aphidicolin | Others | |
Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus[2]. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by i... | |||
T75520 | Aplyronine A | ||
Aplyronine A is a specific actin-depolymerizing agent. Aplyronine A has antitumor and apoptosis effect. Aplyronine A can be used for the research of cancer and muscle contraction, cell motility and cell division [1] . | |||
TN4249 | Ilicol | Others | |
Pinocembrin and Ilicol inhibit root growth and show IC50 (root growth) values of 0.199, 14.68, 8.05, 7.69 mM, and 1.22, 2.90, 7.35, 8.07 mM, against P. miliaceum, A. sativa, L. sativa, and R. sativus, respect... | |||
TN4890 | Rabdosin B | Others | |
Rabdosin B shows cytotoxic activity against three human tumour HepG2, GLC-82 and HL-60 cell lines, it induces significant DNA damage to HepG2 cells in a time- and dose-dependent manner. Rabdosin B at higher concentration... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03534 | CDC37 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is... | |||
TMPY-03558 | CDC37 Protein, Mouse, Recombinant | Mouse | Baculovirus-Insect Cells |
CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is... | |||
TMPY-01715 | CDC37 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is... | |||
TMPY-02308 | CDC42 Protein, Human, Recombinant (GST) | Human | E. coli |
TMPY-04396 | C-ABL/ABL1 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy... | |||
TMPY-02638 | TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant | Human,Rhesus,Cynomolgus,Canine | CHO |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-01133 | TGF beta 1 Protein, Human, Recombinant (His) | Human | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-00500 | TGF beta 1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-04211 | TGF beta 1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-03945 | TGF beta 1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-00608 | TGF beta 1 Protein, Rat/Mouse, Recombinant | Mouse,Rat | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPH-00626 | GPR Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the fun... | |||
TMPH-03527 | FtsZ Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | E. coli |
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the fun... | |||
TMPH-03182 | DTE Protein, Pseudomonas cichorii, Recombinant (His & Myc) | Pseudomonas cichorii | E. coli |
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the fun... | |||
TMPH-00609 | DITP/XTP pyrophosphatase Protein, E. coli, Recombinant (His & Myc & SUMO) | E. coli | E. coli |
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the fun... | |||
TMPH-02699 | H2-K1 Protein, Mouse, Recombinant (GST) | Mouse | E. coli |
Essential cell division protein. | |||
TMPH-02775 | Mup11 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | |||
TMPH-02159 | SMARCC1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Very strongly associated with the peptidoglycan. | |||
TMPH-02160 | SMARCB1 Protein, Human, Recombinant (His) | Human | E. coli |
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Very strongly associated with the peptidoglycan. | |||
TMPH-03438 | CHS1 Protein, S. cerevisiae, Recombinant (His) | Saccharomyces cerevisiae | E. coli |
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. Required for mitotic division septum formation d... | |||
TMPK-00392 | FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in num... | |||
TMPK-00394 | FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in num... | |||
TMPH-03103 | CDH3/Cadherin 3 Protein, Pig, Recombinant (His) | Sus scrofa (Pig) | Yeast |
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. Required for mitotic division septum formation d... | |||
TMPH-01140 | Human coronavirus 229E Spike glycoprotein (His & Myc) | HCoV-229E | E. coli |
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondri... | |||
TMPH-02715 | HAS2 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth an... | |||
TMPH-02714 | HAPLN3 Protein, Mouse, Recombinant (His & Myc) | Mouse | HEK293 |
Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth an... | |||
TMPH-01575 | KRT10 Protein, Human, Recombinant (His) | Human | E. coli |
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cell... | |||
TMPK-00328 | TGFBR2 Protein, Human, Recombinant (mFc & Avi) | Human | HEK293 |
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called sign... | |||
TMPK-00329 | TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated | Human | HEK293 |
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called sign... | |||
TMPH-00643 | K99 fimbrial Protein, E. coli, Recombinant | E. coli | E. coli |
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. The Tol-Pal system is also required for polar localization of ... | |||
TMPH-02883 | RBFOX3 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell di... | |||
TMPJ-00907 | GADD45A Protein, Human, Recombinant (His) | Human | E. coli |
Growth Arrest and DNA Damage-Inducible Protein GADD45 α (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some ... | |||
TMPJ-01407 | FIS1 Protein, Human, Recombinant (His) | Human | E. coli |
Mitochondrial Fission 1 Protein (FIS1) is a member of the FIS1 family. FIS1 is a single-pass membrane protein and contains one TPR repeat. FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FI... | |||
TMPJ-00944 | PPP1CC Protein, Human, Recombinant (His) | Human | E. coli |
Serine/Threonine-Protein Phosphatase PP1-Υ Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractil... | |||
TMPY-03111 | PIK3IP1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
PIK3IP1 contains 1 kringle domain and is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. PI3K is a well-known regulator of cell division, motility, me... | |||
TMPY-04933 | PIK3IP1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
PIK3IP1 contains 1 kringle domain and is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. PI3K is a well-known regulator of cell division, motility, me... | |||
TMPH-01126 | COMMD5 Protein, Human, Recombinant (His & Myc) | Human | Baculovirus |
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites ... | |||
TMPJ-00769 | TK1 Protein, Human, Recombinant (His) | Human | Human Cells |
Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identifi... | |||
TMPY-05095 | RAF1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
RAF1 gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds direct... | |||
TMPH-01282 | ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide bi... | |||
TMPY-04458 | TRIB2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Tribbles homolog 2, also known as TRB-2, and Trib2, is a member of the protein kinase superfamily and Tribbles subfamily (Trib1, Trib2, Trib3). The identification of tribbles as regulators of signal processing systems an... | |||
TMPJ-01316 | IL-21 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Interleukin-21(IL-21) is an approximately 14 kDa cytokine which belongs to the IL-15/IL-21 family. Mature mouse IL-21 shares 66%,59%, 58%, and 88% aa sequence identity with mature canine, human, rabbit, and rat IL-21, re... | |||
TMPJ-01171 | SHH Protein, Mouse, Recombinant (C25II) | Mouse | E. coli |
Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in emb... | |||
TMPJ-01170 | SHH Protein, Mouse, Recombinant | Mouse | E. coli |
Mouse Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in emb... | |||
TMPJ-01127 | SHH Protein, Human, Recombinant | Human | E. coli |
Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic... | |||
TMPJ-01128 | SHH Protein, Human, Recombinant (C24II) | Human | E. coli |
Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called Hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic... | |||
TMPY-01412 | Glypican 5 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Glypican-5 (GPC5), is a cell membrane protein that belongs to the glypican family. The glypicans compose a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans that may play a role in the control... | |||
TMPY-01332 | HIST1H3A Protein, Human, Mouse, Recombinant | Human,Mouse | E. coli |
Histone H3.1, also known as HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, is a member of the histone H3 family which is a core component of nucleosome. It is expresse... | |||
TMPY-04558 | NEK7 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
NIMA (never in mitosis gene a)-related kinase 7, NEK7 belongs to the NIMA subfamily, NEK Ser/Thr protein kinase family, protein kinase superfamily. NEKs (NIMA-related kinases) are mammalian serine/threonine (Ser/Thr) pro... | |||
TMPH-00463 | Erythropoietin Protein, Danio rerio, Recombinant (His) | Danio rerio (Zebrafish) | E. coli |
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, ... | |||
------------------------ More ------------------------ |
Cat No. | Product Name | ||
---|---|---|---|
L1380 | Transcription Factor-Targeted Compound Library | 704 compounds | |
Well-chosen 704 compounds with unique structures targeting transcription factor; | |||
L1110 | Microtubule-Targeted Compound Library | 155 compounds | |
A unique collection of 155 microtubule-targeted compounds can be used in HTS and HCS; | |||
L3700 | JAK-STAT Compound Library | 256 compounds | |
A unique collection of 256 JAK/STAT signaling targeted compounds for high throughput and high content screening; | |||
L8100 | Cell Cycle Compound Library | 695 compounds | |
A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS); |