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By Target- DNA/RNA Synthesis
- Dehydrogenase(1)
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Results for "
dhodh in 12
" in TargetMol Product Catalog- Inhibitors & Agonists2
DHODH-IN-12
T110211263303-93-0In house
DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.
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hDHODH-IN-12
T78932
hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM. As the rate-limiting enzyme in the de novo synthesis of pyrimidines, critical for DNA RNA synthesis, DHODH is localized within the inner membrane of human mitochondria. hDHODH-IN-12 is applicable in lung cancer research [1].
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