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Cat No. | Product Name | Synonyms | Targets |
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T7440 | P,p'-DDE | p,p'-dichlorodiphenyldichloroethylene,4,4'-DDE,Dichlorodiphenyldichloroethylene | Androgen Receptor , Drug Metabolite |
p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDT | |||
T19739 | Simazine | Tafazine,Aquazine,Radocon,Herbex | Others |
Simazine (Tafazine) is a chlorotriazine herbicide and pesticide. Simazine may lead to testicular degeneration, neuroendocrine disruption, mammary cancer, and fetal developmental delays. | |||
T12360 | Para-Nitroblebbistatin | p-Nitroblebbistatin | Myosin |
para-Nitroblebbistatin (p-Nitroblebbistatin) is a non-cytotoxic, fluorescent, photostable and specific Myosin II inhibitor. para-Nitroblebbistatin can be used in the study of the special role of myosin II in developmenta... | |||
T39252L | 5-[(1S,2S)-2-[(Cyclopropylmethyl)amino]cyclopropyl]-N-(tetrahydro-2H-pyran-4-yl)thiophene-3-carboxamide hydrochloride | Others | |
5-[(1S,2S)-2-[(Cyclopropylmethyl)amino]cyclopropyl]-N-(tetrahydro-2H-pyran-4-yl)thiophene-3-carboxamide hydrochloride is a cyclopropanoid enzyme compound that acts as a lysine-specific demethylase-1 inhibitor for schizop... | |||
T0976 | Propoxur | Aprocarb,Propoxure,Baygon | AChR , Antifungal |
Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red b... | |||
T34949 | Trimethylolpropane caprate | UNII-X307CM75YF,Trimethylolpropane tridecanoate,Trimethylolpropane tricaprate | |
Trimethylolpropane caprate has developmental toxicity in Sprague-Dawley rats. | |||
T12640 | (R,R)-Glycopyrrolate | (R,R)-Glycopyrronium bromide,(R,R)-Glycopyrrolate bromide | Others |
(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities. | |||
T14963 | CI-943 | (±)-CI-943 | Others |
CI-943 is a novel potential antipsychotic drug that does not bind to dopamine (DA) receptors and has some developmental neurotoxicity. | |||
T61592 | Thalidomide-piperazine hydrochloride | ||
Thalidomide-piperazine hydrochloride is a chemical compound with potential applications in the research of leprosy and multiple myeloma. It serves as a valuable tool in developmental biology, facilitating significant dis... | |||
T29886 | Almestrone | BA-38372,BA 38372,Ciba-38372,BA38372,Ciba 38372 | |
Almestrone (developmental code names Ba 38372, Ciba 38372), also known as 7α-methylestrone, is a synthetic, steroidal estrogen which was synthesized in 1967 but was never marketed. It is used as a precursor in the synthe... | |||
T36092 | Fenobucarb | ||
Fenobucarb, a widely employed carbamate insecticide, poses potential risks to the cardiovascular and cerebrovascular systems in animals[1][2]. It triggers developmental neurotoxicity in zebrafish by engaging pathways rel... | |||
T31123 | CvxIAA | convex IAA,5-(3-MeOPh)-IAA | |
cvxIAA is an orthogonal auxin-TIR1 receptor pair. cvxIAA triggers auxin signaling without interfering with endogenous auxin or TIR1/AFBs. cvxIAA hijacked the downstream auxin signaling in vivo both at the transcriptomic ... | |||
T82900 | Bemfivastatin hemicalcium | PPD 10558 hemicalcium | |
Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent. It amplifies liver extract activity and exhibits no-observed adverse effect levels (NOAEL) at dosages... | |||
T69717 | Dimethandrolone | ||
Dimethandrolone (DMA), also known by its developmental code name CDB-1321, is an experimental androgen/anabolic steroid (AAS) and progestogen medication which is under investigation for potential clinical use. Dimethandr... | |||
T81027 | TCRS-417 | T417 | |
TCRS-417 (T417), a small molecule compound, selectively binds to the interface between PBX1 and its specific DNA target sequence, disrupting the PBX1-DNA interaction. This compound has potential research applications in ... | |||
T37954 | Sphingosine (d20:1) | Sphingosine (d20:1) | |
Sphingosines are long-chain base precursors of cellular sphingolipids used directly in the synthesis of ceramide, which in combination with sialic acid forms ganglioside. Sphingosine can exist in four stereoisomers, howe... | |||
T71911 | CGP-11130 HCl | ||
4-Fluorophenibut (developmental code name CGP-11130; also known as β-(4-fluorophenyl)-γ-aminobutyric acid or β-(4-fluorophenyl)-GABA) is a GABAB receptor agonist which was never marketed. It is selective for the GABAB r... | |||
T38269 | Purfalcamine | ||
Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes mala... | |||
T83771 | 6-PPD | Antioxidant 4020,N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine | |
6-PPD, a substituted p-phenylenediamine, functions as an ozone scavenger by forming nitroxyl radicals. It impacts zebrafish embryos by decreasing hatchability by 25.6% and 78.9% at concentrations of 0.022 mg/L and 0.22 m... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN3910 | Ecdysone | Apoptosis , ATPase , Glucocorticoid Receptor , Potassium Channel , Sodium Channel , Endogenous Metabolite , Autophagy | |
Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signaling through Ecdysone receptor isoform B1 is required cell a... | |||
T7913 | 2-Bromobiphenyl | Others | |
2-Bromobiphenyl is a persistent organic pollutant (POP) found primarily in soil and water. It is a known human carcinogen and has been linked to a variety of health effects including reproductive and developmental toxici... | |||
T6368 | Abscisic Acid | Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin) | Others , Proton pump , Endogenous Metabolite |
Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth. | |||
T5061 | Lumichrome | 7,8-Dimethylalloxazine | Others |
Lumichrome (7,8-Dimethylalloxazine) is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at nanomolar concentrations. Lumichrom... | |||
T5623 | Bisphenol A | Others , Endogenous Metabolite | |
Bisphenol A is an endogenous metabolic compound of phenols and is widely used in the production of epoxy resins and polycarbonate plastics. It is reproductive, developmental and systemic toxicant and is often classified ... | |||
T3746 | Dimethyl phthalate | Solvanom,Avolin,Fermine | Others |
Dimethyl phthalate (Fermine) has many uses, including in solid rocket propellants, plastics, and insect repellants. Acute (short-term) exposure to dimethyl phthalate, via inhalation in humans and animals, results in irri... | |||
T4867 | Erucic acid | Prifac 2990,13(Z)-Docosenoic Acid,cis-13-docosenoic acid | PI3K , Endogenous Metabolite |
Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ). Erucic acid (13(Z)-Docosenoic Acid) is broken down long-chain... | |||
T4716 | Pyrrole-2-carboxylic acid | 2-Pyrrolecarboxylic acid,Minaline | Endogenous Metabolite |
Pyrrole-2-carboxylic acid (Minaline) was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase. The latter rela... | |||
T4776 | Glycerol | Glycerin | Endogenous Metabolite |
Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00217 | KIR3DL3 Protein, Human, Recombinant (His) | Human | HEK293 |
KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 3) is a Protein Coding gene. KIR3DL3 is a framework gene of the Leukocyte Receptor Complex, present in all individuals and hap... | |||
TMPY-02580 | Histone H1 Protein, Human, Recombinant (His) | Human | E. coli |
H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "... | |||
TMPY-02846 | CLPS Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Colipase belongs to the colipase family. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It is a small protein with five conserved disulphide bonds. Structural... | |||
TMPY-05202 | Noggin/NOG Protein, Human, Recombinant | Human | HEK293 |
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw... | |||
TMPY-05435 | ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis... | |||
TMPY-00890 | Noggin/NOG Protein, Human, Recombinant (hFc) | Human | HEK293 |
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw... | |||
TMPY-02594 | Noggin/NOG Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathw... | |||
TMPY-00341 | FGFR3 Protein, Human, Recombinant (alpha IIIb, His) | Human | HEK293 |
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ... | |||
TMPY-04165 | FGFR3 Protein, Human, Recombinant (His) | Human | HEK293 |
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ... | |||
TMPY-02130 | Argonaute-2 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Argonaute 2 (AGO2), also known as Eukaryotic translation initiation factor 2C2 (EIF2C2), belongs to the Argonaute family, AGO subfamily, which is a component of the RNA-induced silencing complex (RISC) and mediates small... | |||
TMPY-01186 | Argonaute-2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Argonaute 2 (AGO2), also known as Eukaryotic translation initiation factor 2C2 (EIF2C2), belongs to the Argonaute family, AGO subfamily, which is a component of the RNA-induced silencing complex (RISC) and mediates small... | |||
TMPY-00834 | IGF1R/CD221 Protein, Human, Recombinant (His) | Human | HEK293 |
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide... | |||
TMPK-00073 | TDGF1/Cripto Protein, Human, Recombinant (His) | Human | HEK293 |
TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, an... | |||
TMPH-02860 | Wnt6 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal ov... | |||
TMPH-00095 | HDT2 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | Yeast |
Probably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcr... | |||
TMPH-03239 | Angiopoietin-1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal i... | |||
TMPH-00343 | Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His) | Canine | HEK293 |
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal i... | |||
TMPH-00081 | CDKB1-2 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | Yeast |
Together with CDKB1-1, promotes both the last division in the stomatal cell lineage as well as the number of stomata. In collaboration with MYB124 and MYB88, restrict the G1/S transition and chloroplast and nuclear numbe... | |||
TMPY-00368 | ALR Protein, Human, Recombinant (His) | Human | HEK293 |
Alterations in GFER gene have been associated with progressive mitochondrial myopathy, congenital cataracts, hearing loss, developmental delay, lactic acidosis and respiratory chain deficiency in 3 siblings born to consa... | |||
TMPK-00695 | N Cadherin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important ... | |||
TMPK-01049 | CLEC7A Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis... | |||
TMPH-02864 | Wnt1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is ... | |||
TMPY-00487 | PTPN9 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Protein tyrosine phosphatase non-receptor type 9 (PTPN9), also named PTP-MEG2, is an important member of the protein tyrosine phosphatase family that is involved in variety of human diseases.PTPN9 plays an important role... | |||
TMPH-01015 | BMP-3 Protein, Human, Recombinant (His) | Human | E. coli |
Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of ce... | |||
TMPK-00926 | Noggin/NOG Protein, Mouse, Recombinant (His & Flag) | Mouse | HEK293 |
Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer G... | |||
TMPK-00925 | Noggin/NOG Protein, Mouse, Recombinant | Mouse | HEK293 |
Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer G... | |||
TMPK-01396 | Notch 3 Protein, Human, Recombinant (His) | Human | HEK293 |
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular dom... | |||
TMPK-01367 | Notch 3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular dom... | |||
TMPK-01360 | Notch 3 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular dom... | |||
TMPK-00468 | Notch 1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Human Notch-1 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes.Notch-1 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagg... | |||
TMPK-01374 | Notch 3 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular dom... | |||
TMPK-00467 | Notch 1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Human Notch-1 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes.Notch-1 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagg... | |||
TMPY-03275 | EphA3 Protein, Human, Recombinant (His) | Human | HEK293 |
EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The eph... | |||
TMPJ-01215 | IL-17RD Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
The Il17rd gene encodes a transmembrane protein of the IL-17 receptor family. IL-17RD, originally termed similar expression to fibroblast growth factor (fgf) genes (Sef) as it belonged to the FGF synexpression group in z... | |||
TMPY-02493 | EphA3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The eph... | |||
TMPY-01118 | SLC27A4/FATP4 Protein, Human, Recombinant (His) | Human | HEK293 |
SLC27A4/ATG4B complex might act as a new potential therapeutic target of lung tumor chemotherapy. The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. Autism s... | |||
TMPY-04448 | EphA3 Protein, Mouse, Recombinant (aa 569-984) | Mouse | Baculovirus-Insect Cells |
EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The eph... | |||
TMPJ-01114 | GAMT Protein, Human, Recombinant (His) | Human | E. coli |
GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoa... | |||
TMPH-01018 | BMP-6 Protein, Human, Recombinant (His) | Human | E. coli |
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes including cartilage and bone formation. Plays also an important role in the regulation of iron metabolism by acting as ... | |||
TMPK-00706 | TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily.The... | |||
TMPK-00707 | TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily.The... | |||
TMPJ-01216 | IL-17RD Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
The Il17rd gene encodes a transmembrane protein of the IL-17 receptor family. IL-17RD, originally termed similar expression to fibroblast growth factor (fgf) genes (Sef) as it belonged to the FGF synexpression group in z... | |||
TMPY-03437 | DNAJC30 Protein, Human, Recombinant (His) | Human | E. coli |
DNAJC30 is a member of the DNAJ molecular chaperone homology domain-containing protein family. DNAJC30 gene is deleted in williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes... | |||
TMPY-04447 | EphA3 Protein, Mouse, Recombinant (aa 569-984, His & GST) | Mouse | Baculovirus-Insect Cells |
EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The eph... | |||
TMPJ-01384 | MAN1B1 Protein, Human, Recombinant (His) | Human | Human Cells |
Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is invo... | |||
TMPY-04082 | EphA3 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The eph... | |||
TMPY-00631 | EphA3 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The eph... | |||
TMPY-02562 | EphA3 Protein, Rat, Recombinant (His) | Rat | HEK293 |
EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The eph... | |||
TMPK-00466 | Notch 2 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Human Notch-2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of ... | |||
TMPK-00465 | Notch 2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Human Notch 2 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes. Although Notch proteins are structurally and functionally similar, deletion of ... | |||
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