deacetylate

1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, demonstrating greater selectivity for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM). It does not increase global histone H4 acetylation or reduce total intracellular HDAC activity but can induce tubulin acetylation[1][2].

N-deacetylated BMS-202 is an inhibitor of PD-1/PD-L1 interactions and has potential anticancer activity for cancer research.

Chitosan (Deacetylated chitin) (≥95% deacetylated, viscosity 100-200 mPa.s) is a polysaccharide derived from the deacetylation of chitin, which exhibits antimicrobial activity against various bacteria and fungi.

Chitosan hydrochloride 80%-90% deacetylated (Chitosan HCl 80%-90% deacetylated) is the hydrochloride salt form of chitosan. This polysaccharide, produced through the deacetylation of chitin, exhibits antibacterial activity against various bacteria and fungi. It is utilized in agriculture, water treatment, and pharmaceuticals.

Chitosan (Deacetylated chitin) (≥90% deacetylated, viscosity 10 mPa.s) is a polysaccharide derived from the deacetylation of chitin and exhibits antimicrobial activity against various bacteria and fungi. Chitosan (≥90% deacetylated, viscosity 10 mPa.s) serves as a versatile biomaterial, applicable in drug delivery, tissue engineering, and wound healing.

Chitosan (≥80% deacetylated, Medium viscosity,200-400mPa.s) is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Chitosan (≥80% deacetylated, High viscosity,>400mPa.s) is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Chitosan (≥85% deacetylated, viscosity>90 mPa.s, MW 15000) is a reagent used in biochemical reactions.

Chitosan (Deacetylated chitin) (≥90% deacetylated, viscosity 650-700 mPa.s) is a polysaccharide derived from the deacetylation of chitin, exhibiting antibacterial activity against various bacteria and fungi. With its high degree of deacetylation and specific viscosity, Chitosan can serve as a multifunctional biomaterial in drug delivery, tissue engineering, and wound healing applications.

Chitosan (≥98% deacetylated, mushroom) is a biochemical reagent that can be used as a flocculant, protein precipitant, encapsulating agent, and aqueous thickener.

Chitosan (85%-90% deacetylated, mushroom) is a biochemical reagent that functions as a flocculant, protein precipitant, encapsulating agent, and aqueous thickener.

Chitosan (≥95% deacetylated, mushroom) is a biochemical reagent used as a flocculant, protein precipitant, encapsulating agent, and aqueous thickener.

Chitosan (MW 150000) (Deacetylated chitin) is a linear polysaccharide made up of randomly distributed β-(1-4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine.

1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(5) value of 17.3 +/- .3 microM.

Norgestimate is an acetylated progestinused in combination with ethinyl estradiol as an oral contraceptive.

Bisthianostat, also known as CF367 or CF367;-C, is a novel Orally Efficacious Pan-HDAC Inhibitor. Bisthianostat selectively binds to and inhibits HDACs, which inhibits deacetylation of histone proteins and leads to the accumulation of highly acetylated histones. This may result in an induction of chromatin remodeling, the inhibition of tumor oncogene transcription, and the selective transcription of tumor suppressor genes. This prevents cell division, induces cell cycle arrest and apoptosis. This may inhibit the proliferation of susceptible tumor cells. HDACs, upregulated in many tumor cell types, are a family of enzymes that deacetylate histone proteins.