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By Target- Cytochromes P450
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By Target By ResearchField- Cardiovascular System(1)
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Results for "
cyp-11b2-in-1
" in TargetMol Product Catalog.- Inhibitors & Agonists2
CYP11B2-IN-1
T109221356479-78-1In house
CYP11B2-IN-1 is an effective and selective inhibitor of CYP11B2 with IC50s of 2.3 nM and 142 nM for CYP11B2 and CYP11B1.
- $42
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QTY
CYP19A1/CYP11B2-IN-1
T86150183500-36-9
CYP19A1/CYP11B2-IN-1 is a potent dual inhibitor of aromatase (CYP19A1) and aldosterone synthase (CYP11B2), with IC₅₀ values of 2.3 nM and 29 nM, respectively. CYP19A1/CYP11B2-IN-1 inhibits breast cancer cell proliferation and induces apoptosis (IC₅₀ of 0.26 ± 0.03 μM against MCF-7 cells). CYP19A1/CYP11B2-IN-1 downregulates the PI3K/Akt/mTOR signaling pathway by inhibiting mTOR phosphorylation.
- $74
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