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By Target- Antibacterial
- Antibiotic(2)
- Proteasome(1)
- Others(2)
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Results for "
cpha
" in TargetMol Product Catalog- Inhibitors & Agonists3
Cilastatin
Cited
MK0791
T258382009-34-5
Cilastatin (MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.
- $30
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QTY
CitedCilastatin sodium
MK 791, MK 0791, Cilastatinum, Cilastatine, Cilastatin Sodium, Cilastatin Monosodium Salt ;Cilastatin Sodium, Cilastatin Monosodium Salt, Cilastatin
T2583L81129-83-1
Cilastatin is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor.
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Metallo-β-lactamase-IN-11
T79435
Metallo-β-lactamase-IN-11 (compound 5f), a potent inhibitor of Metallo-β-lactamases (MBLs), demonstrates efficacy against bacterial metallophyllactamase CphA with an IC50 value of 45 µM. At 10 µM, it inhibits NDM-1 by 49% and AIM-1 by 61%, indicating its potential for research on countering antibiotic resistance [1].
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