core

AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging.

Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins (IC50 = 1.1 μM). Ro5-3335 represses RUNX1/CBFβ-dependent transactivation in reporter assays and inhibits transcriptional regulation by RUNX1 and CBFβ. Ro5-3335 also reduces the leukemia burden in a mouse model. Attenuates RUNX1-dependent hematopoiesis in zebrafish embryos. It also is a Tat antagonist and inhibits HIV-1 replication in vitro.

MUC1, mucin core is a type I transmembrane glycoprotein that is characterized by its overexpression and abnormal glycosylation in carcinoma cells. It specifically binds to domain 1 of ICAM-1.

HCV Core Protein (59-68) is a peptide containing residues 59-68 from the core protein of the Hepatitis C virus (HCV) [1].

HCV Core Protein (107-114), identified as the binding site within the region 101-118, is a minimally immunogenic fragment of the primary linear HCV core regions. This segment, comprising two residues that vary between genotypes I/II and III/VI, represents a potential focal point for the dissemination of HCV serotypes [1].

The hepatitis B virus (HBV) core protein has been found in the nucleus, the cytoplasm, or both of HBV-infected hepatocytes. nuclear localization of the HBV core protein is negatively regulated by phosphorylation during the cell cycle.

Disialylated Core 1 O-glycan (C1S(3,6)2), 2-AB labelled, is an O-linked glycan with a core structure 1 that is disialylated and labelled with 2-AB (2-aminobenzamide). It is associated with sialylation and plays roles in biological activities such as cell recognition, protection, immune regulation, and serves as a disease marker.

Disialylated Core 2 O-glycan (C2S(3,3)2), 2-AB labelled, is an O-linked glycan with a core 2 structure labeled with 2-AB (2-aminobenzamide). It is associated with sialylation and plays roles in biological activities such as cell recognition, protection, immune modulation, and serving as a disease marker.

Sialylated Core 1 O-glycan (C1S(3)1), 2AB labeled, is a multifunctional fluorescent linker comprised of a polymeric N-glycoprotein. The resulting conjugates, which emulate the antenna components of N-glycans, exhibit high sensitivity and specificity.

Core 1 O-glycan (C1) is a crucial O-linked glycan with a core structure 1 (MUC1-M). Core 1 O-glycan (C1), labeled with 2AB, is associated with sialylation and involved in biological activities such as cell recognition, protective functions, immune regulation, and disease markers.

Sialylated Core 1 O-glycan (C1S(3)1) is a polymeric N-glycoprotein and serves as a multifunctional fluorescent linker. The resulting conjugate emulates the antenna structures of N-glycans, offering high sensitivity and specificity.

Core 1 O-glycan (C1), 2AB labelled, is an O-linked glycan with a Core 1 structure, labeled with 2AB (2-aminobenzamide). It is related to sialylation and plays roles in biological processes such as cell recognition, protection, immune regulation, and as a disease marker.

PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor that inhibits USP2/4/5/7/8 (EC50=7.2/3.93/8.61/6.86/4.9 μM). PR-619 induces endoplasmic reticulum stress and activates autophagy.

(-)-Corey lactone diol [C13H20O4] is a pharmaceutical intermediate characterized as a colorless oil with a molecular weight of 240.29 g/mol, melting point ranging from 77.0 to 78.0℃, and a boiling point of 97-105℃ at a pressure of 0.01 Torr.

Coreanoside F1 is a useful organic compound for research related to life sciences. The catalog number is T126048 and the CAS number is 132282-69-0.

CoREST/LSD1 degrader-1 (Compound 4) is a molecular glue degrader targeting the KBTBD4 E3 ubiquitin ligase. This compound shows potential for research into cancers driven by KBTBD4 mutations (such as medulloblastoma) and disorders related to epigenetic dysregulation.

Lycorenine may produce a decrease in blood pressure as the result of alpha-adrenergic blockade in conjunction with the reduction of the spontaneous sympathetic nerve activity, and produce bradycardia by modifying vagal activity. The development of tachyph

(-)-Corey lactone benzoate, catalog number T66946 and CAS number 39746-00-4, is a valuable organic compound for life sciences research.

Isocoreopsin, also known as Flavanocorepsin, is an anticancer compound extracted from the flowers of Butea monosperma [1].

Corey lactone aldehyde benzoate serves as a versatile, chiral intermediate in the synthesis of prostaglandins and their analogs.

Felcorekibart is a humanized IgG1κ antibody that specifically targets TSLP. Its corresponding isotype control is HumanIgG1kappa, Isotype Control.

2-Acetoxyacorenone (compound 8) is a sesquiterpenoid compound that can be isolated from the rhizomes of Acorus tatarinowii. It exhibits potential inhibition activity against AChE and β-BACE1, making it useful for Alzheimer's disease research.

Coreopsin(Butein-4-O-β-D-glucopyranoside) is one of the main components from Coreopsis tinctoria Nutt. Flower(CTF). CTF has been used traditionally in China for treating hypertension and diabetes as well as reducing body weight and blood fat.

Coretinphencone is a natural product that is isolated from the buds of Coreopsis tinctoria Nutt.