collagen (bovine skin)

Collagen (bovine skin) plays a crucial role in the structure and function of skin, bones, and tendons. Collagen derived from bovine skin can serve as a scaffold for biomimetic collagen mineralization.

Highly purified Type III collagen, derived from bovine skin (Bovine Type III collagen, immunization grade), is a collagen protein capable of stimulating the immune system in animals to generate specific antibodies against it. Additionally, this collagen serves as a hydrolytic substrate for matrix metalloproteinases (MMPs).

Type I collagen(from bovine skin) plays a crucial role in the structure and function of skin, bones, and tendons. Type I collagen effectively stimulates angiogenesis both in vitro and in vivo. This immunization-grade collagen is suitable for inducing antibody production.

PXS-6302 is an irreversible inhibitor of lysyl oxidase with IC50s of 3.7 μM for Bovine LOX, 3.4 μM for rh LOXL1, 0.4 μM for rh LOXL2, 1.5 μM for rh LOXL3, 0.3 μM for rh LOXL4, respectively. PXS-6302 can readily penetrate the skin, reduces collagen deposition and cross-linking, and significantly improves scar appearance without reducing tissue strength. PXS-6302 also has potentially broader applications in other fibrotic diseases.

PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3.7 μM, 3.4 μM, 0.4 μM, 1.5 μM, and 0.3 μM, respectively. PXS-6302 hydrochloride penetrates easily through the skin and is able to reduce collagen accumulation, significantly improving the appearance of scars.

Type I Collagen, for cell culture, from Bovine, plays a critical role in the structure and function of skin, bones, and tendons. It can mimic the extracellular matrix (ECM) and is suitable for both 2D and 3D cell culture applications.

Type I Collagen, T Cell Grade, from Bovine possesses unique immunological properties and plays a crucial role in the structure and function of skin, bones, and tendons. Additionally, it can be utilized as a stimulatory antigen for T cells in in vitro culture systems.