collagen

Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.

J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptors. Anti-inflammatory effect. J-113863 is a potent and selective CCR1 (CD18) antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively.

BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.

L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.

Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.

Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.

Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.

SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2).

Copper tripeptide (GHK-Cu) is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine, with a strong affinity for copper(II). First isolated from human plasma, it is also found in saliva and urine.

Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative that selectively inhibits collagen. It non-competitively inhibits agonist-induced platelet aggregation, with an IC50 value of 1.77 μM. Collagen-IN-1 reduces P-selectin expression, glycoprotein IIb/IIIa activation, and the release of adenosine triphosphate and CD63 from platelets. This compound is promising for research into platelet-related thrombosis diseases [1].

Anti-Human/Mouse denatured collagen type-I Antibody (XL313) is an IgG1, κ inhibitor derived from mice, targeting denatured collagen type-I in both human and mouse.

This is a peptide inhibitor of collagen fibrillar matrix assembly.

Type II collagen is composed of a triple helix of three identical α chains. These molecules associate to form a fibril that is stabilized by intermolecular crosslinks1. Damage to the fibrillar meshwork, made up of primarily type II collagen (z 90–95%), ma

Collagen type IV alpha1 (531-543) is a protein that in humans is encoded by the COL4A1 gene on chromosome 13. It is ubiquitously expressed in many tissues and cell types. COL4A1 is a subunit of type IV collagen and plays a role in angiogenesis.

Collagenpeptide Type II is an extracellular matrix protein widely utilized in the food, cosmetics, pharmaceutical, and biomedical industries. This product consists of collagen short peptides that have undergone enzymatic hydrolysis.

Collagenpeptide Type I is an extracellular matrix protein widely utilized in the food, cosmetics, pharmaceutical, and biomedical industries. The product consists of collagen short peptides that have been enzymatically hydrolyzed.

Recombinant Humanized Type III Collagen 30-40kDa is an innovative biomaterial with anticancer properties. It can activate discoidin domain receptor 1 (DDR1), thereby inhibiting cancer cell autophagy, proliferation, and migration, while inducing apoptosis.

Type V collagen, highly purified from human placenta (Human Placenta Type V collagen, immunization grade), is a form of collagen protein that induces an immune response in animals, leading to the production of specific antibodies against this collagen. It also serves as a substrate for matrix metalloproteinases (MMP).

Bovine CB11 of type II collagen (Bovine cyanogen bromide digested peptide 11) is a peptide fragment derived from cyanogen bromide digestion of type II collagen (CB-peptide). It is utilized in the study of B cell and T cell epitopes specific to type II collagen. This compound does not contain pepsin, making it ideal for investigating T cell epitope specificity via proliferation assays. Additionally, Bovine CB11 can serve as an antigen for assessing antibody epitope specificity through ELISA analysis.

Chick CB10 of type II collagen (Chick cyanogen bromide digested peptide 10) is a CB-peptide fragment derived from type II collagen. It is useful for studying B cell and T cell epitopes of type II collagen. This product contains no pepsin, making it ideal for examining T cell epitope specificity via proliferation assays. Additionally, Chick CB10 of type II collagen serves as an antigen for assessing antibody epitope specificity through ELISA analysis.

Mouse CB10 of type II collagen (Mouse cyanogen bromide digested peptide 10) is a cyanogen bromide-digested peptide fragment from type II collagen. It is useful for studying B cell and T cell epitopes of type II collagen. This product is pepsin-free, making it ideal for examining T cell epitope specificity through proliferation assays. Additionally, Mouse CB10 of type II collagen can serve as an antigen for analyzing antibody epitope specificity via ELISA.

Bovine CB9.7 of type II collagen (Bovine cyanogen bromide digested peptide 9.7) is a peptide fragment resulting from the cyanogen bromide digestion of type II collagen, used for the investigation of B and T cell epitopes related to type II collagen. This product is free from pepsin, making it ideal for analyzing T cell epitope specificity via proliferation assays. Additionally, Bovine CB9.7 can serve as an antigen in ELISA to assess antibody epitope specificity.

Human CB8 of type II collagen, also known as Human cyanogen bromide digested peptide 8, is a peptide fragment derived from cyanogen bromide digestion of type II collagen. It is utilized for studying B cell and T cell epitopes of type II collagen. This product is devoid of pepsin, making it ideal for examining T cell epitope specificity through proliferation assays. Additionally, Human CB8 of type II collagen serves as an antigen in ELISA to analyze antibody epitope specificity.

Bovine CB10 of type II collagen (Bovine cyanogen bromide digested peptide 10) is a cyanogen bromide-digested peptide fragment of type II collagen, used in the study of B cell and T cell epitopes within type II collagen. Free of pepsin, it is ideal for analyzing T cell epitope specificity through proliferation assays. Additionally, Bovine CB10 of type II collagen serves as an antigen for determining antibody epitope specificity via ELISA analysis.