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Results for "
cl316243
" in TargetMol Product Catalog- Inhibitors & Agonists3
CL 316243
T10830138908-40-4In house
CL316243 is a highly potent selective agonist of β3-adrenoceptor, with a EC50 of 3 nM. CL316243 is an effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence.
- $48
Size
QTY
CL 316243 free acid
T88808183720-02-7
CL 316243 free acid exhibits an IC 50 of 0.6 μM and 1 μM for rat heart and rat soleus muscle, respectively. Additionally, it inhibits spontaneous contractions in isolated rat detrusor muscle strips in a concentration-dependent manner, with an average concentration for 50% maximal inhibition at 2.65 nM.
- $2,360
Size
QTY
L748337
L-748,337
T22905244192-94-7
L748337 is a competitive and potent β3-adrenoceptor antagonist that inhibits the action of β3-, β2-, and β1-adrenoceptors, activates MAPK signaling, promotes phosphorylation of Erk1/2, and inhibits the protective effects of CL316243, and is used in the study of disorders caused by abnormalities of the β3-adrenoceptors.
- $63
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QTY
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