chelerythrine

1. Chelerythrine (Broussonpapyrine) may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiproliferative and antitumor effects.

Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to ATP.

Chelerythrine hydroxide is the salt form of Chelerythrine, a benzophenanthridine alkaloid present in the plant Chelidonium majus (greater celandine). It is a potent, selective, and cell-permeable protein kinase C inhibitor in vitro. And an efficacious antagonist of G-protein-coupled CB1 receptors.]This molecule also exhibits anticancer qualities and it has served as a base for many potential novel drugs against cancer.

Chelerythrine-d6 is a deuterium-labeled version of Chelerythrine. Chelerythrine is a natural alkaloid that serves as an effective and selective Ca2+/phospholipid-dependent PKC antagonist, with an IC50 of 0.7 μM. It possesses antitumor, antidiabetic, and anti-inflammatory properties. Additionally, Chelerythrine inhibits the binding of BclXL-Bak BH3 peptide with an IC50 of 1.5 μM and displaces Bax from BclXL. It also induces apoptosis and autophagy.

Chelerythrine chloride (Standard) is a reference standard for research and analysis in studies involving Chelerythrine chloride. Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to ATP.

6-Ethoxychelerythrine (Ethoxychelerythrin) has anti-bacterial activity, it exhibited strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA).

1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application in the therapy of serious infection caused by I. multifiliis. 4. Dihydrochelerythrine affects cell cycle distribution, activates mitochondrial apoptotic pathway, and induces apoptosis and necrosis in HL-6 cells.

6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine, an alkaloid, significantly alters the characteristics of early endosomes, mitochondria, and autophagosomes in Parkinson's Disease patient-derived olfactory cells [1].

6-Ethoxychelerythrine (Standard) is a reference standard for research and analysis in studies involving 6-Ethoxychelerythrine. 6-Ethoxychelerythrine (Ethoxychelerythrin) has anti-bacterial activity, it exhibited strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA).

9-Ethoxychelerythrine serves as a chemical reference standard for the quality control of traditional Chinese herbal medicines derived from species such as Zanthoxylum nitidum. Beyond its analytical applications, emerging studies indicate that this compound may exert notable biological effects, including the ability to induce mitochondrial apoptosis in colorectal cancer cells. This mechanistic insight highlights its potential value as a preliminary lead structure for oncology research, particularly in investigations focused on programmed cell death pathways and natural-product-based anticancer agents.

6-n-Propoxy dihydrochelerythrine is a natural compound found in Chelidonium majus (commonly known as greater celandine).

Norchelerythrine shows significant inhibitory activity against Staphylococcus aureus ATCC 6538 with MIC values ranging from 12.5 to 50 ug/mL. It exhibits strong antifeeding activity in a concentration-dependant manner with the EC50 of 62.67 ppm.

6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively. 6-Acetonyldihydrochelerythrine is

Oxychelerythrine shows high modulatory activity enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold. It also shows antifeeding activities against Tribolium castaneum adults, with the EC50 of 192.32 p

Sanguinarine chloride (Pseudochelerythrine chloride), a benzophenanthridine alkaloid, stimulates apoptosis by activating the production of reactive oxygen species (ROS).

Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.

Angoline hydrochloride (6-Methoxyldihydrochelerythrine) is an IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum with anticancer activity and inhibits STAT3 signaling.

Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.

Sanguinarine citrate (Pseudochelerythrine chloride) is an alkaloid derived from Sanguinaria Canadensis with antimicrobial, anti-inflammatory, and analgesic activity that is used in the treatment of oral inflammatory diseases such as stomatitis, bleeding gums, and laryngitis.