cdc25b2

DA-3003-1 (DA-3003-1) is a membrane-permeable, potent and selective Cdc25 dual specificity phosphatase inhibitor with antitumor activity that inhibits Cdc25B2, Cdc25A, Cdc25B2 and Cdc25C.

BN82002 (CDC25 Phosphatase Inhibitor I) is a synthetic inhibitor of CDC25 phophatases

NSC305787 hydrochloride ((Rac)-NSC305787 hydrochloride is a cell membrane permeable and selective and potent small molecule dual inhibitor of Cdc25 dual specificity phosphatase and EZR that displays antitumor activity in pancreatic cancer cells and inhibits Cdc25B2, Cdc25A, Cdc25B2 and Cdc25C.NSC 663284 inhibits NSD2 (IC50 of 170 nM) enzyme activity.

BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family, inhibiting CDC25A, CDC25B2, CDC25B3, CDC25C, and [25C-cat] with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 μM, respectively, and exhibits approximately 20-fold greater selectivity over [CD45 tyrosine phosphatase].

6,7-Dichloroquinoline-5,8-dione (compound DA3002) serves as an effective inhibitor of CDC25B2, with an IC50 of 4.6 µM. This compound also shows potential for cancer research applications.