bicyclic

Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.

Phalloidin, a bicyclic heptapeptide found in Gooseberry, is involved in F-actin staining. Phalloidin is a compound that irreversibly polymerizes actin into microfilaments.Phalloidin interferes with cell motility and growth, and can be used to label cerebral blood vessels.

RA VII is used as an antitumor bicyclic hexapeptide of plant origin.

Fmoc-Cys(STmp)-OH is a cysteine derivative that can be used in the synthesis of bicyclic and linear peptides.

BT1769 is a bicyclic toxin conjugate targeting MT1-MMP (Matrilysin 1 type-MMP) with a KD of 3.35 nM. It is utilized for osteosarcoma research. BT1769 comprises an innovative bicyclic targeting peptide that selectively binds to MT1-MMP, a cytotoxin MMAE, and a dipeptide linker that can be enzymatically cleaved.