benzoxazole

Ezutromid (BMN 195) is a translation modulator of Small utrophin (EC50: 0.4 uM). Ezutromid is an orally bioavailable small molecule that transcriptionally upregulates the utrophin gene, increasing both utrophin mRNA and protein. Through this action, Ezutromid increases muscle function in dystrophin-deficient MDX mice, a mouse model of muscular dystrophy.

1,3-Benzoxazole-6-carboxylic acid is used as a catalyst in drug synthesis, and a building block in the synthesis of other compounds.

5-Chloro-2-methylbenzoxazole, with CAS No. 19219-99-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-Chloro-2-methylbenzoxazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-CHLOROBENZOXAZOLE, with CAS No. 17200-29-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-CHLOROBENZOXAZOLE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2,5-Dimethylbenzoxazole is a heterocyclic compound containing a benzene ring and an oxazole ring, widely used in biochemical experiments and drug synthesis research.

2-Chlorobenzoxazole is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)

BTA-188 is one of the most potent analogues of novel and orally active synthetic benzoxazole and benzothiazole derivatives with significant anti-rhinovirus activity.

YO-Pro 1, a cyanine dye consisting of benzoxazole and quinoline rings connected by a linker, is almost nonfluorescent in water, but its fluorescence is greatly enhanced after intercalation in double-stranded DNA, forming the basis of DNA concentration assays. Ex/Em (bound DNA) = 491/509 nm. YO-Pro 1 can be used to identify apoptotic cells.

HSP90-IN-29 (Compound 13), a benzoxazole derivative, serves as a potent and selective HSP-90 inhibitor, exhibiting a low IC50 value of 30 nM. This compound demonstrates significant antitumor activity [1].