benzo[a]pyrene

Benzo[a]pyrene (3,4-Benzopyrene) exhibits lung carcinogenicity in animal models and is commonly used for lung cancer modeling and chemoprevention research.

Benzo[a]pyrene diol epoxide is a carcinogenic compound found in tobacco smoke and environmental pollutants. It is a metabolite of the polycyclic aromatic hydrocarbon (PAH) compound benzo[a]pyrene (BaP), and can induce esophageal carcinogenesis. This compound has been shown to activate ERKs and p38 MAPK, marked by increased phosphorylation levels of these proteins.

Benzo[e]pyrene, a highly toxic polyaromatic hydrocarbon (PAH), is found in fossil fuels [1].

Benzo[a]pyrene (Standard) is the standard of Benzo[a]pyrene (T6985), suitable for research related to quantitative analysis, quality control, and biochemical experiments. Benzo[a]pyrene (3,4-Benzopyrene) exhibits lung carcinogenicity in animal models and is commonly used for lung cancer modeling and chemoprevention research.

3-Hydroxybenzo[a]pyrene (3-OHBaP) is a biomarker used for assessing exposure to benzo[a]pyrene (BaP), a known carcinogen.

Tocofersolan (TPGS) is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version of Tocopherol. Tocofersolan is an oral treatment of vitamin E deficiency due to digestive malabsorption in pediatric patients with congenital chronic cholestasis or hereditary chronic cholestasis.

Ellagic Acid Dihydrate inhibit the CYP1A1-dependent activation of benzo[a]pyrene.

(Z)-Ligustilide (Ligustilide A) , an active ingredient isolated from the medicinal plants Angelica acutiloba and Cnidium officinale, inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation.

Corannulene is an agonist of the aromatic hydrocarbon receptor (AhR). It induces a lower cytotoxic response in liver cancer cells compared to Benzo[a]pyrene and shows potential for use in cancer research.

Telomerase-IN-9 is a potent and selective inhibitor of telomerase, effectively reducing telomerase activity by binding to hTERT, which results in diminished telomerase function. This compound induces apoptosis and inhibits colony formation. It has been shown to reduce tumor burden, restore antioxidant balance, and protect lung structure in a mouse model of lung cancer induced by Benzo[a]pyrene. Telomerase-IN-9 is applicable in lung cancer research.

Dibenzo(a, i)pyrene is a polycyclic aromatic hydrocarbon with potent carcinogenic activity.

12-Hydroxy Stearic Acid is a low molecular weight organogel that prevents benzo(a)pyrene and squalene peroxide-induced hyperpigmentation in the skin.

(Z)-Ligustilide (Standard) is a reference standard for research and analysis in studies involving (Z)-Ligustilide. (Z)-Ligustilide (Ligustilide A) , an active ingredient isolated from the medicinal plants Angelica acutiloba and Cnidium officinale, inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation.