azobenzene

Azobenzene is a phototrigger that can be used to design and synthesize a variety of photoresponsive systems.Azobenzene is genotoxic and induces aggressive sarcomas of the spleen and other abdominal organs.

3'-Hydroxymethyl-4-(dimethylamino)azobenzene is a bioactive chemical.

Azobenzene (Standard) is the standard substance of Azobenzene, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Azobenzene is a phototrigger that can be used to design and synthesize a variety of photoresponsive systems.Azobenzene is genotoxic and induces aggressive sarcomas of the spleen and other abdominal organs.

SDMA p-Hydroxyazobenzene-p′-sulfonate is the p-hydroxyazobenzene-p′-sulfonate form of SDMA. It acts as an inhibitor of endogenous nitric oxide synthase (NO synthase) and serves as an activator of NF-κB, enhancing the expression of IL-6 and TNF-α. This compound remains stable in serum and plasma, making it a potential biomarker for liver and kidney dysfunction.

Diazobenzenesulfonic acid (a component of Pauly's reagent) is a classical chemical modification probe for proteins. It specifically labels surface-exposed histidine and tyrosine residues via diazotization, widely utilized for probing protein tertiary structure accessibility and analyzing enzyme active site conformations.

4-(Dimethylamino)-3'-fluoroazobenzene is a bioactive chemical.

4-Aminoazobenzene (Standard) is a reference standard of 4-Aminoazobenzene intended for quantitative analysis, quality control, and related biochemical research applications.

m-((3-Amino-4-hydroxyphenyl)azo)benzenesulphonic acid is a bioactive chemical.

m-((4-((4-(Bis(2-hydroxyethyl)amino)phenyl)azo)-1-naphthyl)azo)benzenesulphonic acid is a bioactive chemical.

m-((4-((4-Hydroxy-m-tolyl)azo)-3-methoxyphenyl)azo)benzenesulphonic acid is a bioactive chemical.

PAD2-IN-2 (cis-isomer of 1) TFA is an inhibitor of protein arginine deiminase 2 (PAD2). This molecule features an azobenzene photoswitch, enabling the optical regulation of PAD activity. Additionally, PAD2-IN-2 TFA inhibits the citrullination of histone H3.

Thalidomide-Photoswitch3-NH2 hydrochloride is essential in creating PHOTACs, which are PROTACs activated by specific light wavelengths. These compounds become inactive in darkness and switch to an active cis isomer state under 390 nm irradiation, while wavelengths above 450 nm reverse this activation. This compound comprises a CRBN-recruiting ligand, an azobenzene photoswitchable crosslinker, and a pendant amine that interacts with an acid on the target warhead, and is used to synthesize PHOTAC-I-10 and PHOTAC-II-6.

QAQ dichloride is a photoswitchable compound that blocks voltage-gated Na v and K v channels. Its channel-blocking activity is observed in the trans form of the azobenzene photoswitch, while the cis form does not exhibit this effect. This compound is membrane-impermeant and selectively enters pain-sensing neurons expressing endogenous import channels. QAQ dichloride functions as a light-sensitive analgesic and provides a valuable tool for investigating signaling mechanisms involved in acute and chronic pain [1] [2].

ACe-1 is a ceramide derivative featuring an azobenzene segment that allows for optical control of the N-acyl chain. This compound can reversibly toggle lipid domains within raft-like bilayer membranes.

18:0-azo PC is an analog of phosphatidylcholine (PC). Upon exposure to light, it can be photoactivated or deactivated, causing the azobenzene segment within the molecule to undergo cis/trans isomerization, thereby initiating or terminating cell signaling pathways.