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Results for "
atic-in-1 acetate
" in TargetMol Product Catalog- Inhibitors & Agonists1
ATIC-IN-1 acetate
T78159
ATIC-IN-1 acetate is an inhibitor of aminoimidazole-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) with potential anti-tumor activity. It inhibits AICAR Tfase by disrupting ATIC homo-dimerization.
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T829501402453-15-9
ATIC-IN-1 (compound 14) is an inhibitor targeting the dimerization of Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC), with a K i of 685 nM. This dimerization is crucial for the enzyme's AICAR transformylase function. Additionally, ATIC-IN-1 exhibits anti-tumor properties by reducing cell proliferation and cell division rates [1].
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