arabinose

Arabinose (DL-Arabinose), also known as (+/-)-arabinose or aloe sugar. Arabinose has been primarily detected in feces. Within the cell, Arabinose is primarily located in the cytoplasm. Arabinose exists in all eukaryotes, ranging from yeast to humans. Outside of the human body, Arabinose can be found in sweet basil and tamarind.

L-(+)-Arabinose selectively inhibits intestinal sucrase in a non-competitive manner, thereby preventing glucose elevation induced by sucrose intake.

D-(+)-Fucose is a non-metabolizable analog of l-arabinose and an inducer of β-methylgalactoside permease. It inhibits the induction of the l-arabinose manipulator and blocks the growth of Escherichia coli B/r on mineral salts medium with l-arabinose.

Thyminose induces apoptosis by inhibiting glutathione synthesis and increasing its efflux.

L-Arabinopyranose (Standard) is the standard substance of L-Arabinopyranose, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. L-Arabinopyranose (Pectinose) is an aldopentose, including an aldehyde (CHO) functional group.

D-(-)-Arabinose is a reducing sugar useful as a substrate in analysis of arabinose isomerases and synthesis of D-erythroascorbic acid in yeast. It shows strong growth inhibition against the Caenorhabditis elegans with an IC50 of 7.5 mM.

Inexpensive starting material for chiral synthesis.

Arabinose 1,5-diphosphate is a bisphosphatase inhibitor.

Arabinose (Standard) is a reference standard for research and analysis in studies involving Arabinose. Arabinose (DL-Arabinose), also known as (+/-)-arabinose or aloe sugar. Arabinose has been primarily detected in feces. Within the cell, Arabinose is primarily located in the cytoplasm. Arabinose exists in all eukaryotes, ranging from yeast to humans. Outside of the human body, Arabinose can be found in sweet basil and tamarind.

D-Arabinose (Standard) is the standard substance of D-Arabinose, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Inexpensive starting material for chiral synthesis.

L-(+)-Arabinose (Standard) is the standard substance of L-(+)-Arabinose, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. L-(+)-Arabinose inhibits intestinal sucrase activity, thereby reducing sucrose utilization, and consequently decreasing lipogenesis.

5-Deoxy-L-arabinose is a reagent used in biochemical reactions.

2,3,5-Tris-O-(phenylmethyl)-D-arabinose has potential applications in glycobiology research.

D-Arabinose 5-phosphate (sodium) is a biochemical reagent used in the study of glycobiology. Glycobiology focuses on the structure, synthesis, biology, and evolution of sugars. This field involves carbohydrate chemistry, the enzymology of glycan formation and degradation, protein-glycan interactions, and the role of glycans in biological systems, and is closely related to basic research, biomedicine, and biotechnology.

D-arabinose-13C5 is the 13C labeled compound of D-arabinose. D-arabinose has a CAS number of 10323-20-3. Inexpensive starting material for chiral synthesis.

Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration, ancitabine is slowly hydrolyzed into cytarabine. Subsequently, cytarabine is converted to the triphosphate form within the cell and then competes with cytidine for incorporation into DNA. Because the arabinose sugar sterically hinders the rotation of the molecule within DNA, DNA replication ceases, specifically during the S phase of the cell cycle. Cytarabine agent also inhibits DNA polymerase, resulting in a decrease in DNA replication and repair. Compared to cytarabine, a more prolonged, consistent cytarabine-mediated therapeutic effect may be achieved with ancitabine because of the slow hydrolytic conversion of ancitabine to cytarabine.

Galactose 1-dehydrogenase, pseudomonas fluorescens, a dehydrogenase found in Pseudomonas fluorescens, facilitates the oxidation of L-arabinose and D-galactose, utilizing NADP+/NAD+ as a cofactor. This enzyme is employed in diagnostic assays to quantify total galactose levels and serves as a biocatalyst in the production of galacturonic acid salts.

Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis, resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug.

4-Mmethylumbelliferyl α-L-arabinopyranoside (4-Mmethylumbelliferyl α-L-arabinopyranoside) serves as a substrate for enzymes that hydrolyze arabinose-containing substrates, such as α-L-arabinopyranoside.