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Search Results for " antitumoral "

14

Compounds

Cat No. Product Name Synonyms Targets
T7747 Datelliptium chloride hydrochloride DNA/RNA Synthesis
Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.
T3691 (Rac)-SAR131675 SAR131675 VEGFR
(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is h...
T9864 Debio-0123 WEE1-IN-5 Wee1
Debio-0123 (WEE1-IN-5) is a potent, orally available and highly specific WEE1 inhibitor with an IC 50 in the low nanomolar range. Debio-0123 inhibits phospho-CDC2 which translated into an increase in DNA damage and prema...
T11542 HDAC-IN-4 HDAC
HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.
T26810 Bikaverin BRN 0358013,Lycopersin
Bikaverin is a reddish pigment produced by different fungal species with antibiotic properties against certain protozoa and fungi. Bikaverin also has antitumoral activity against different cancer cell lines.
T11930 M8891 Others
M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor(IC50 :54nM;Ki:4.33 nM).M8891 inhibits growth of primary endothelial cells as well as tumor cells and demonstrates ...
T39889 Antitumor agent-23
Antitumor agent-23 exhibits potent antitumoral activity, as demonstrated by its GI50 values of 38, 48, 5, 27, 80, and 28 nM against the lymphoma cell lines GRANTA-519, KARPAS-422, KARPAS-299, RAMOS, DAUDI, and RAJI respe...
T21096 Decamethylene glycol alpha,omega-Decanediol,Decamethylenediol,1,10-Dihydroxydecane,Decane-1,10-diol
Decamethylene glycol is a substance used as a reagent in the biological study of modified oligonucleotide with in vivo antitumoral activity. Also used in the pharmaceutical study on the composition of essential oils obta...
T83142 Alloferon 2
Alloferon 2, an antiviral and antitumoral peptide, can be isolated from the hemolymph of the blow fly Calliphora vicina (Diptera) [1].
T72645 Norbatzelladine L
Norbatzelladine L, an inhibitor of both the catalytic and functional activities of the Pdr5p transporter, suppresses Pdr5p ATPase activity with an IC50 of 3.8 µM. Additionally, it exhibits antifungal, antiparasitic, anti...
T76162 Stem bromelain
Stem bromelain (EC 3.4.22.32), a cysteine proteinase from pineapple (Ananas comosus) stem, is a significant type of bromelain known for its fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory properties. I...
T72551 Antitumor agent-87
Antitumor agent-87 is a potent compound with antitumoral activity, demonstrating a high affinity for CYP1A1, evidenced by a K i value of 0.23 µM. It exhibits antiproliferative effects and induces cell cycle arrest at the...
T75500 Batzelladine D
Batzelladine D, also known as Compound 1, functions as an inhibitor of the Pdr5p transporter's catalytic and functional activities, demonstrating inhibitory action against Pdr5p ATPase activity with an IC50 value of 7.1 ...
T83143 Alloferon 1
Alloferon 1, a peptide derived from the blood of the blow fly Calliphora vicina (Diptera) [1] [2] [3], exhibits antiviral and antitumoral properties. It activates natural cytotoxicity of human peripheral blood lymphocyte...
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