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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7747 | Datelliptium chloride hydrochloride | DNA/RNA Synthesis | |
Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities. | |||
T3691 | (Rac)-SAR131675 | SAR131675 | VEGFR |
(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is h... | |||
T9864 | Debio-0123 | WEE1-IN-5 | Wee1 |
Debio-0123 (WEE1-IN-5) is a potent, orally available and highly specific WEE1 inhibitor with an IC 50 in the low nanomolar range. Debio-0123 inhibits phospho-CDC2 which translated into an increase in DNA damage and prema... | |||
T11542 | HDAC-IN-4 | HDAC | |
HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity. | |||
T26810 | Bikaverin | BRN 0358013,Lycopersin | |
Bikaverin is a reddish pigment produced by different fungal species with antibiotic properties against certain protozoa and fungi. Bikaverin also has antitumoral activity against different cancer cell lines. | |||
T11930 | M8891 | Others | |
M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor(IC50 :54nM;Ki:4.33 nM).M8891 inhibits growth of primary endothelial cells as well as tumor cells and demonstrates ... | |||
T39889 | Antitumor agent-23 | ||
Antitumor agent-23 exhibits potent antitumoral activity, as demonstrated by its GI50 values of 38, 48, 5, 27, 80, and 28 nM against the lymphoma cell lines GRANTA-519, KARPAS-422, KARPAS-299, RAMOS, DAUDI, and RAJI respe... | |||
T21096 | Decamethylene glycol | alpha,omega-Decanediol,Decamethylenediol,1,10-Dihydroxydecane,Decane-1,10-diol | |
Decamethylene glycol is a substance used as a reagent in the biological study of modified oligonucleotide with in vivo antitumoral activity. Also used in the pharmaceutical study on the composition of essential oils obta... | |||
T83142 | Alloferon 2 | ||
Alloferon 2, an antiviral and antitumoral peptide, can be isolated from the hemolymph of the blow fly Calliphora vicina (Diptera) [1]. | |||
T72645 | Norbatzelladine L | ||
Norbatzelladine L, an inhibitor of both the catalytic and functional activities of the Pdr5p transporter, suppresses Pdr5p ATPase activity with an IC50 of 3.8 µM. Additionally, it exhibits antifungal, antiparasitic, anti... | |||
T76162 | Stem bromelain | ||
Stem bromelain (EC 3.4.22.32), a cysteine proteinase from pineapple (Ananas comosus) stem, is a significant type of bromelain known for its fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory properties. I... | |||
T72551 | Antitumor agent-87 | ||
Antitumor agent-87 is a potent compound with antitumoral activity, demonstrating a high affinity for CYP1A1, evidenced by a K i value of 0.23 µM. It exhibits antiproliferative effects and induces cell cycle arrest at the... | |||
T75500 | Batzelladine D | ||
Batzelladine D, also known as Compound 1, functions as an inhibitor of the Pdr5p transporter's catalytic and functional activities, demonstrating inhibitory action against Pdr5p ATPase activity with an IC50 value of 7.1 ... | |||
T83143 | Alloferon 1 | ||
Alloferon 1, a peptide derived from the blood of the blow fly Calliphora vicina (Diptera) [1] [2] [3], exhibits antiviral and antitumoral properties. It activates natural cytotoxicity of human peripheral blood lymphocyte... |