antihypertension

Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GABA analog with neuroprotective, anticonvulsant, and antihypertensive activity.

Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug that is converted to its active metabolite fosinoprilat.

Diminazene is an aromatic diamine compound primarily used to control trypanosomiasis. It mainly binds to the kDNA of trypanosomes, disrupting their replication process. Diminazene is being investigated for new pharmacological applications, such as an activator of angiotensin-converting enzyme 2 (ACE2), and has potential uses in antihypertension, anti-rheumatoid arthritis, and immunoregulation.