alpha-Glucose

alpha-D-glucose (α-Dextrose) is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.

Isomaltose (D-Isomaltose) is a reducing disaccharide, similar to maltose, but with an α-(1-6)-linkage instead of the α-(1-4)-linkage.

D-Galactose is a naturally occurring hexose and a C-4 epimer of glucose. It can combine with glucose to form lactose and is commonly used to establish animal models of aging.

D-Melibiose (Galalpha1-6Glcbeta) is a reducing disaccharide formed by an alpha-1, 6 linkage between galactose and glucose (D-Gal-α(1→6)-D-Glc).

Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It is an agonist of the P2Y14 receptor (EC50 = 0.35 μM) and can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM.

PALATINOSE (TNP-470) is a natural occurring disaccharide composed of alpha-1,6-linked glucose and fructose. PALATINOSE has a beneficial effect on liver metabolic functions and might therefore be a good substitute for sucrose as a sweetener.

ZLN005 (hydrochloride) is an activator of the peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1α). It enhances the expression of PGC-1α and downstream genes in skeletal muscle cells, leading to improved glucose utilization and fatty acid oxidation. In diabetic db/db mice, ZLN005 (hydrochloride) elevates the transcription of PGC-1α and downstream genes in skeletal muscle, boosts fat oxidation, and enhances glucose tolerance, pyruvate tolerance, and insulin sensitivity.

NS-220, a selective agonist of peroxisome proliferator-activated receptor alpha, potently decreases plasma triglyceride and glucose levels and modifies lipoprotein profiles in KK-Ay mice.

α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism. 1.Beitner, R.Regulation of carbohydrate metabolism by glucose 1,6-bisphosphate in extrahepatic tissues; comparison with fructose 2,6-bisphosphateInt. J. Biochem.22(6)553-557(1990) 2.Maliekal, P., Sokolova, T., Vertommen, D., et al.Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the α-D-phosphohexomutase familyJ. Biol. Chem.282(44)31844-31851(2007) 3.Moustafa, H.M.A., Zaghloul, T.I., and Zhang, Y.-H.P.A simple assay for determining activities of phosphopentomutase from a hyperthermophilic bacterium Thermotoga maritimaAnal. Biochem.50175-81(2016) 4.Panosian, T.D., Nannemann, D.P., Watkins, G.R., et al.Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered entry point into the catalytic cycleJ. Biol. Chem.286(10)8043-8054(2011)

α-D-Glucose-1-phosphate sodium hydrate (Glucose-1-phosphate sodium hydrate) is an intermediate in glycogen metabolism and a precursor in UDP-glucose biosynthesis.

UDP-α-D-Glucose sodium hydrate is an endogenous metabolite and a pyrimidine nucleotide sugar, involved in glycosylation reactions during metabolic processes, serving as a precursor and substrate for enzymes in the synthesis of glycogen and sucrose.

α-D-Glucose 1-phosphate disodium salt is converted into D-glucose-6-phosphate by the enzyme phosphoglucomutase.

α-Tocopherol phosphate (alpha-Tocopherol phosphate) is an antioxidant that scavenges UVA1-induced reactive oxygen species (ROS) and protects against long-wave UVA1-induced cell death. α-Tocopherol phosphate disodium (Vitamin E phosphate disodium) impedes endothelial progenitor cell apoptosis, enhances migration under high glucose/low oxygen conditions, and promotes angiogenesis.

Methyl Dehydroabietate is a natural diterpenoid that induces the expression of proliferator-activated receptor alpha (PPARα) in liver and PPARγ in adipose tissue in mice, reduces obesity-induced glucose and insulin tolerance, and possesses a variety of biological activities such as antimicrobial, anti-inflammatory, and antioxidant.

4,6-O-Ethylidene-α-D-glucose is a glucose derivative that competitively inhibits the extracellular binding site of glucose transporter 1 (GLUT1), with a Ki of 12 mM for the transport of wild-type 2-deoxy-D-glucose.

L-Phenylalanine (Standard) is an essential alpha-amino acid used as a standard for quantitative analysis.L-Phenylalanine is an agonist of GPR142 and promotes insulin secretion, which is closely related to glucose metabolism and diabetes research. L-Phenylalanine is an agonist of GPR142 and promotes insulin secretion, which has been implicated in studies of glucose metabolism and diabetes. May indirectly regulate N-methyl-D-aspartate receptors (NMDA receptors) by affecting dopamine levels.

alpha-D-glucose (Standard) is the standard substance of alpha-D-glucose, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. alpha-D-glucose (α-Dextrose) is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.

D-Melibiose (Standard) is the standard substance of D-Melibiose, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. D-Melibiose (Galalpha1-6Glcbeta) is a reducing disaccharide formed by an alpha-1, 6 linkage between galactose and glucose (D-Gal-α(1→6)-D-Glc).

Kushenol A is a kind of Adenosine 3', 5'-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors, it shows selective alpha-glucosidase inhibitory activity. Kushenol A and kushenol C exhibit inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).

Alpha-D-glucose hydrate is a monosaccharide and the most common form of glucose, playing a vital role in energy metabolism as the primary energy source for many cells. It is also a building block of larger carbohydrates such as starch and glycogen. The "α" prefix refers to the orientation of the hydroxyl group attached to the first carbon atom. In solution, alpha-D-glucose exists as a hydrate, bound to water molecules.

1,2-O-Isopropylidene-alpha-d-glucofuranose (Mono-acetone glucose) is a biochemical reagent utilized as a biomaterial or organic compound pertinent to life sciences research.

Alpha-D-Glucose 1,6-bisphosphate (cyclohexanamine) is a biochemical reagent used in glycobiology research. Glycobiology focuses on the structure, synthesis, biology, and evolution of sugars and involves carbohydrate chemistry, glycan formation, enzymology of degradation, protein-glycan recognition, and the roles of glycans in biological systems. This field is closely linked with fundamental research, biomedicine, and biotechnology.