alda

Alda-1 is an ALDH2 agonist, a cell-permeable activator of both the wild-type ALDH2*1 and the Asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydrogenase 2 (mtALDH2).

PALDA (N-Palmitoyl dopamine) is a fatty acid dopamine found in the mammalian brain that is inactive against TRPV1 and inactivates at TRPV(1)R. It is used in the study of duodenal ulcers.

Caldaret HCl is an intracellular Ca2+ modulator that regulates calcium homeostasis at the sarcoplasmic reticulum and cell membrane, and can be used to study acute myocardial infarction and heart failure.

Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotypes (Ki=2.6 nM &2.0 nM).Faldaprevir inhibits viral replication by blocking the breakdown of viral precursor proteins, and is well tolerated with good antiviral activity against hepatitis C virus.

Caldaret is an intracellular Ca2+ handling modulator that acts through reverse mode Na+/Ca2+ exchanger inhibition.

Zaldaride maleate inhibits CaM (calmodulin)-stimulated cAMP phosphodiesterase activity (IC50: 3.3 nM). Zaldaride maleate is an effective and selective inhibitor of calmodulin. Zaldaride maleate prevents estrogen-induced transcription activation by ER, re

allosteric potentiator of mGlu5

Galdansetron hydrochloride is a serotonin antagonist and anti-emetic.

Faldaprevir sodium is a potent NS3/NS4A protease inhibitor potentially for the treatment of HCV infection. Faldaprevir is known to inhibit P-glycoprotein, CYP3A4, and UDP-glucuronosyltransferase 1A1.

Galdansetron is a serotonin antagonist.

Zaldaride (free base) is a calmodulin antagonist.

DALDA, a highly selective μ-opioid receptor agonist with a K_i value of 1.69 nM, exhibits potent antinociceptive (pain-relieving) and respiratory effects.

DALDA acetate, a highly selective and potent μ-opioid receptor agonist, exhibits a K i value of 1.69 nM, demonstrating significant antinociceptive and respiratory effects [1].

DALDA TFA is a potent, μ-opioid receptor agonist exhibiting high selectivity and an affinity constant (K i) of 1.69 nM. It demonstrates antinociceptive properties and influences respiratory functions [1].

β-L-Gulopyranosyl-caldarchaetidyl-glycerol is the principal polar lipid in the archaeon T. acidophilum. Its cellular levels in T. acidophilum HO-62 show a positive correlation with culture pH and a negative correlation with temperature. This compound also serves as a standard for polar lipid quantification from T. acidophilum HO-62. [Matreya, LLC. Catalog No. 1303]

[Dmt1]DALDA is a potent and long-lasting analgesic that interacts with the μ-opioid receptor (mu-opioid receptor), exhibiting high affinity and selectivity. It acts as a full agonist for hMOR (Kd= 0.199 nM) and hDOR, yet only serves as a partial agonist for hKOR.

Syringaldazine is a reagent used in biochemical reactions.

Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selectivity.

DCB (3,3'-dichlorobenzaldazine) is an allosteric ligand for mGluR5 and shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB). DCB blocks the positive allosteric regulation of mGluRs with the help of 3,3′-difluorobenzaldazine (DFB).

Canrenoate potassium (Soldactone) is a synthetic pregnadiene derivative with anti-aldosterone activity.

Amesergide is an orally active and selective serotonin (5-HT1/2) antagonist that inhibits weight gain in offspring of female CD rats, making it suitable for depression research.

DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and can be used to study neurological diseases.

Canrenone (SC14266) is an aldosterone antagonist with potassium-sparing diuretic activity.

Altizide is a thiazide diuretic. It is used to treat oedema and hypertension.