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  • Inhibitors & Agonists
    131
    TargetMol | Inhibitors_Agonists
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Aucubin
Rhinanthin, Aucuboside
T3416479-98-1
Aucubin (Rhinanthin) is an iridoid glycoside with anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities.
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Rutin
Rutoside, Quercetin 3-O-rutinoside
T0795153-18-4
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
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D-Galactose
D-Galactopyranose, D-(+)-Galactose, Alpha-D-galactose
T059159-23-4
D-Galactose (Alpha-D-galactose) is an aldohexose that exists naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins and is converted enzymatically into D-glucose for metabolism or polysaccharides for storage. It accelerates senescence in invertebrates and mammals and has been used as a model for aging.
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(-)-Fucose
L-Galactomethylose, L-(-)-Fucose, Brahmic acid, 6-Desoxygalactose
TJO26912438-80-4
1.(-)-Fucose (6-Desoxygalactose) can anti-infective, anti-cancer, enhance immunity 2. (-)-Fucose is a skin moisturizing and delaying skin aging 3. (-)-Fucose is a nutritional supplement
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Cyclic N-Acetyl-D-mannosamine
2-ACETAMIDO-2-DEOXY-D-MANNOPYRANOSE HYDRATE
T47257772-94-3
Cyclic N-Acetyl-D-mannosamine is a monosaccharide used as a precursor in the chemical or enzymatic synthesis of neuraminic acid found in glycolipids and glycoproteins.N-Acetyl-D-mannosamine is a specific substrate for the synthesis of n -acetylneuraminic acid, an essential precursor for bacterial podoplanar polysialic acid (PA).N-Acetyl-D-mannosamine is used in the synthesis of sialic acid. mannosamine is used in the synthesis of sialic acid. It is also an intermediate in the synthesis of many carbohydrate-derived bioactive compound families and drug candidates.N-Acetyl-D-mannosamine is used in the study of cognitive disorders and aging.
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Folic acid
Vitamin M, Vitamin B9, Pteroylglutamic acid, Folate, Folacin
T006259-30-3
Folic acid (Vitamin B9) is a vitamin B9 that is essential for the synthesis of DNA RNA and for the production and maintenance of new cells. Folic acid deficiency can lead to anemia, neural tube closure defects, tumors, aging, and other diseases.
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L-Carnosine
Karnozin, beta-Alanyl-L-histidine
T4732305-84-0
L-Carnosine (Karnozin) is is an antioxidant naturally found in skeletal muscle, brain tissue. It has the potential to suppress many of the biochemical changes that accompany aging.
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Fisetin
T2879528-48-3
Fisetin belongs to a group of natural flavonols with a variety of biological activities, including anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects.
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Lycopene
ψ,ψ-Carotene
T2864502-65-8
Lycopene (ψ,ψ-Carotene) is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. As a class, carotenoids are pigment compounds found in photosynthetic organisms (plants, algae, and some types of fungus), and are chemically characterized by a large polyene chain containing 35-40 carbon atoms; some carotenoid polyene chains are terminated by two 6-carbon rings. In animals, carotenoids such as lycopene may possess antioxidant properties which may retard aging and many degenerative diseases. As an essential nutrient, lycopene is required in the animal diet.
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Pro-xylane
Hydroxypropyl tetrahydropyrantriol
T16579439685-79-7
Pro-xylane (Hydroxypropyl tetrahydropyrantriol) is a C-glycoside, a xylose derivative, that stimulates the production of glycosaminoglycans (GAGs) and heparan sulfate proteoglycans (HSPGs) and induces a higher deposition of proteins in basement membranes and dermal-epidermal junctions (DEJs). Pro-xylane is used to maintain skin elasticity and improve skin aging.
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Protocatechualdehyde
Protocatechuic aldehyde, 3,4-Dihydroxybenzaldehyde, Rancinamycin IV, Catechaldehyde
T3018139-85-5
Protocatechualdehyde (3,4-Dihydroxybenzaldehyde), a natural polyphenol compound derived from radix Salviae Miltiorrhizae roots, exhibits diverse biological activities and finds extensive medicinal applications as an antioxidant, anti-aging, antibacterial, and anti-inflammatory agent.
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L-Cystine
Cystine Acid, cystine
T2O273356-89-3
L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of cysteine amino acid thiol side chains. It functions as an antioxidant and protects tissues against radiation and pollution, slowing the aging process. It also aids protein synthesis. L-Cystine (Cystine Acid) is abundant in many proteins of skeletal tissues and skin, and found in insulin and digestive enzymes chromotrypsinogen A, papain, and trypsinogen.
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Qingyangshengenin B
Otophylloside B
TMS1461106758-54-7
Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mRNA level. Qingyangshengenin B has antiepileptic and anti-aging effects, it can extend lifespan, increase heat stress-resistance, delay body paralysis, and increase the chemotaxis response in C. elegans models of Alzheimer's disease. Otophylloside B can suppress the seizure-like locomotor activity caused by pentylenetetrazole in zebrafish.
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(20R)-Ginsenoside Rg3
20(R)-Ginsenoside Rg3, (20R)Ginsenoside Rg3, 20(R)-Propanaxadiol
T381238243-03-7
(20R)-Ginsenoside Rg3 (20(R)-Propanaxadiol) is a compound with anti-aging and antifatigue activities.
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Pulchinenoside A
Anemoside A3
T3911129724-84-1
Pulchinenoside A (Anemoside A3) is an attractive candidate for further development as a cognitive enhancer capable of alleviating memory dysfunctions associated with aging and neurodegenerative diseases.
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DL-Syringaresinol
(±)-Syringaresinol
TN15941177-14-6
DL-Syringaresinol ( (±)-Syringaresinol) is a lignan from ginseng berries with anti-inflammatory, antioxidant, analgesic and weak anti-mycobacterial activities.DL-Syringaresinol can delay oxidative stress-induced skin aging through autophagy, alleviate oxaliplatin-induced neuropathic pain and sepsis-induced cardiac dysfunction by inhibiting inflammatory responses. neuropathic pain and sepsis-induced cardiac dysfunction by inhibiting inflammatory responses.
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(±)-Jasmonic acid
trans-Jasmonic acid
T4088077026-92-7
(±)-Jasmonic acid (trans-Jasmonic acid) is a compound found in grapevine inflorescences and fruits with pro-aging activity, inhibiting chlorophyll levels in green and yellowing barley leaf segments, suppressing rice seedling elongation, and participating in biogenic amine chemical coupling through decarboxylation with both aliphatic and aromatic α-amino acids.
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Dihydrorobinetin
(+)-Dihydrorobinetin
TMA06004382-33-6
Dihydrorobinetin ((+)-Dihydrorobinetin) is a compound extracted from Robinia pseudoacacia. It is a marker of vinegar aging in Robinia pseudoacacia wood. It has antioxidant activity and is often added to skin care products.
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7-10 days
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3,​5,​6,​7,​8,​3',​4'-​Heptemthoxyflavone
3,3',4',5,6,7,8-heptamethoxyflavone
TN10881178-24-1
3,5,6,7,8,3',4'-Heptemthoxyflavone exhibits neuroprotective, chemopreventive, anti-allergic, anti-inflammatory, immunomodulatory, anti-aging, and photoprotective effects; it inhibits collagenase activity, induces type I procollagen synthesis in HDFn cells, and combats nitric oxide (NO) carcinogenesis.
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Oxyphyllacinol
T7849887657-77-0
Oxyphyllacinol is a compound isolated from the fruits of Alpinia oxyphylla with potential antioxidant and anti-aging activity for dementia research.
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Orobol
3'-Hydroxygenistein, 3',4',5,7-tetrahydroxy-isoflavon
TN2019480-23-9
Orobol (3',4',5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover. Orobol inhibits PI3K isoforms with IC50s of 3.46-5.27 μM for PI3K α β γ K δ. Orobol exhibits anti-skin-aging and anti-obesity effects.
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Epifriedelanol acetate
TN39682259-07-6
Epifriedelanol exhibits antibacterial activities. It also can reduce cellular senescence in human primary cells and may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases. Epifriedelanol and friedel
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5-Feruloylquinic acid
5-O-Feruloylquinic acid, 5-FQA
TN129640242-06-6
5-Feruloylquinic acid (5-FQA) is a potent Sirt1 agonist and a potential lead compound for further testing in the drug development process for aging-associated diseases.
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(+)-Coclaurine hydrochloride
d-Coclaurine hydrochloride, (R)-Coclaurine hydrochloride, (+)-(R)-Coclaurine hydrochloride
T7853919894-19-0
(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species. This compound exhibits anti-aging properties, as reported in sources [1] [2].
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