adrenoleukodystrophy

Pentacosanoic acid, belongs to the class of organic compounds known as very long-chain fatty acids.

ELOVL1-IN-1 (1-(2-Fluorophenyl)-N-(1-(2-fluoropyridin-4-YL)-1H-pyrazol-3-YL)cyclopropane-1-carboxamide) is an ELOVL1 inhibitor. ELOVL1-IN-1 can reduce the levels of very long chain fatty acids. ELOVL1-IN-1 can be used in the study of adrenoleukodystrophy (ALD).

Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.

L-Pipecolic acid (L-Homoproline) is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adrenoleukodystrophy.

Nervonic acid (Selacholeic acid) is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline, sphingosine, phosphoric acid, and fatty acid. Nervonic acid may enhance the brain functions and prevent demyelination (Chemical Land21). Research shows that there is negative relationship between nervonic acid and obesity-related risk factors. Demyelination in adrenoleukodystrophy (ALD) is associated with an accumulation of very long chain saturated fatty acids stemming from a genetic defect in the peroxisomal beta oxidation system responsible for the chain shortening of these fatty acids. Sphingolipids from post mortem ALD brain have decreased levels of nervonic acid, 24:1(n-9), and increased levels of stearic acid, 18:0.

Tridecanedioic acid (Brassilic acid) is an unusual odd-numbered dicarboxylic acid that appears in the urines of children with neonatal adrenoleukodystrophy and Zellweger syndrome, as an additional marker of these peroxisomal disorders.

Hexacosanoic acid, a very long-chain fatty acid, is related to adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.

ELOVL1-IN-3 is a potent and orally active inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme. ELOVL1-IN-3 serves as a useful tool for researching adrenoleukodystrophy (ALD).

1-Hexacosanoyl-sn-glycero-3-phosphocholine (26:0 Lyso PC) is a long-chain fatty acid that can serve as a biomarker for X-linked adrenoleukodystrophy (ALD) in mice.

Hexacosanoic acid (Standard) is the standard substance of Hexacosanoic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Hexacosanoic acid, a very long-chain fatty acid, is related to adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.

Lignoceric Acid (Standard) is the standard reference of Lignoceric Acid, suitable for quantitative analysis, quality control and biochemical research. Lignoceric Acid (tetracosanoic acid) is a 24-carbon saturated fatty acid (24:0), synthesized in the developing brain and also a by-product of lignin production. It is used in the research of Zellweger cerebrohepatorenal syndrome and adrenoleukodystrophy.

Triolein (Standard) is the standard substance of Triolein, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.

L-Pipecolic acid (Standard) is a reference standard for research and analysis in studies involving L-Pipecolic acid. L-Pipecolic acid (L-Homoproline) is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adrenoleukodystrophy.