acne

Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.

Clindamycin Phosphate is the phosphate salt form of clindamycin, a semi-synthetic, chlorinated broad-spectrum antibiotic produced by chemical modification of lincomycin. Clindamycin phosphate (Clindamycin 2-dihydrogen phosphate) is used in topical preparations.

Trifarotene (CD5789) is a potent and selective RARγ agonist, exhibiting 65-fold and 16-fold selectivity for RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM).

Salnacedin (G-201) is a small molecule compound used in the treatment of immune system disorders, skin and musculoskeletal disorders, and can be used in studies of acne vulgaris, dermatitis and psoriasis.

AS-601811 is a steroidal 5α-reductase inhibitor and androgen receptor modulator used to study hair loss and acne.

broparestrol is a bioactive tetrasubstituted alkene that can be used as an estrogen in dermatology (such as the treatment of acne).

Resorcinol monoacetate (Resorcin monoacetate) is an antiseptic and a disinfectant, is a chemical intermediate for the production of many other pharmaceuticals, and can be used to treat acne, seborrheic dermatitis, eczema, psoriasis, and other skin disorders.

Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochloride can cause both an acute hepatitis-like syndrome occurring within 1 to 3 months of starting therapy or a more insidious chronic hepatitis with autoimmune features typically after long-term treatment.

Nadifloxacin (OPC7251) has been used in trials studying the treatment of Acne Vulgaris.

Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs), which act as transcription factors that promote cell differentiation and apoptosis. This naturally occurring retinoic acid has potential antineoplastic activity, exhibits immunomodulatory and anti-inflammatory responses, and inhibits ornithine decarboxylase, thereby decreasing polyamine synthesis and keratinization.

Sulfacetamide (NSC-63871) is used to treat blepharitis or conjunctivitis (in eye-drop solution) by limiting the presence of folic acid which bacteria need to survive. sulfacetamide may serve as a treatment for mild forms of hidradenitis suppurativa. It is also used to control acne.

Methyl Aminolevulinate Hydrochloride (5-Aminolevulinic acid methyl ester) is commonly used in photosentizer reagents for photodynamic therapy to treat conditions such as Acne vulgaris and hypertrophic scarring.

1-Pentadecanol is a natural product with anti-acne activity.

Retinyl oleate is A fatty acid ester formed from oleic acid and all-trans retinol (vitamin A) that is used in the preparation of oily acne treatment preparations.

Methyl-4-oxoretinoate is a synthetic retinoid compound with anticancer compounds that can induce differentiation and apoptosis in cancer cells.Methyl-4-oxoretinoate is used in the treatment of acne, psoriasis, and other skin disorders.Methyl-4-oxoretinoate has the potential to be used in the treatment of a variety of ocular disorders such as age-related macular degeneration. related macular degeneration).

Pantethine (Pantomin) (Bis-pantethine) is a dimeric form of vitamin B5. Pantethine is less stable than pantothenic acid and tends to decompose over time if it is not kept refrigerated, so most vitamin B5 supplements are in the form of calcium pantothenate. It is available as a dietary supplement and is used to treat acne and improve the blood-cholesterol profile.

Viaminate, a derivative of retinoic acid, is utilized in the treatment of severe acne and other keratinization disorders.

Furfuryl tetrahydropyranyladenine has demonstrated effectiveness in treating erythema associated with acne rosacea.

Cyproterone, an anti-androgen, is used in combination with estrogen for the therapy of hirsutism and severe acne in females and as a palliative in prostatic carcinoma.

Sarecycline hydrochloride (Sarecycline HCl) is an orally active narrow-spectrum tetracycline antibiotic with antimicrobial and anti-inflammatory activity, inhibits Acinetobacter and Candida tropicalis, and can be used to treat inflammatory acne.

Algestone acetophenide (Neolutin) is progesterone that used in estrus synchronization and has been evaluated as an injectable contraceptive in combination with estradiol enanthate. It is also used therapeutically as a topical anti-inflammatory and is applied topically in the therapy of ACNE.

Motretinide, an aromatic analog of retinoic acid, is an anti-acne preparation.

TU-2100 is an ethyl salicylate-containing compound with potential anti-acne effects for the study of acne.

XMP-629, an endotoxin inhibitor, is used potentially for the treatment of impetigo and acne rosacea.