acne — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7586	Trifarotene	CD5789	Retinoid Receptor , Autophagy
	Trifarotene (CD5789) is a potent and selective RARγ agonist with 65-fold and 16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM).		Retinoid Receptor , Autophagy
T1093	Adapalene	CD271	Apoptosis , Retinoid Receptor , Autophagy
	Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.		Apoptosis , Retinoid Receptor , Autophagy
T1611	Isotretinoin	13-cis-Retinoic acid	Retinoid Receptor , Endogenous Metabolite , Autophagy
	Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall...		Retinoid Receptor , Endogenous Metabolite , Autophagy
T1142	Clindamycin phosphate	Clindamycin 2-phosphate,Clindamycin 2-dihydrogen phosphate,NSC 618653,U-28508	ribosome , Antibacterial , Antibiotic , Parasite
	Clindamycin Phosphate is the phosphate salt form of clindamycin, a semi-synthetic, chlorinated broad-spectrum antibiotic produced by chemical modification of lincomycin. Clindamycin phosphate (Clindamycin 2-dihydrogen ph...		ribosome , Antibacterial , Antibiotic , Parasite
T5002	Methyl Aminolevulinate Hydrochloride	5-Aminolevulinic acid methyl ester,Methyl δ-aminolevulinate hydrochloride,Methyl 5-aminolevulinate Hydrochloride,Aminolevulinic acid methyl ester Hydrochloride	Others
	Methyl Aminolevulinate Hydrochloride (5-Aminolevulinic acid methyl ester) is commonly used in photosentizer reagents for photodynamic therapy to treat conditions such as Acne vulgaris and hypertrophic scarring.		Others
T35903	N-acetyl Dapsone		Antibacterial , Parasite
	N-acetyl Dapsone is an anti-inflammatory and antimicrobial compound widely used in the treatment of leprosy, malaria, acne and various immune disorders.		Antibacterial , Parasite
T29022	TU-2100	Azeloyl diethyl salicylate,Azasal-2100,TU 2100,TU2100	Others
	TU-2100 is an ethyl salicylate-containing compound with potential anti-acne effects for the study of acne.		Others
TP2316	Myristoyl Hexapeptide-23 Acetate		Others
	Anti acne.		Others
T1466	Nadifloxacin	OPC7251	Antibacterial , Antibiotic
	Nadifloxacin (OPC7251) has been used in trials studying the treatment of Acne Vulgaris.		Antibacterial , Antibiotic
T24755	Salnacedin	G-201,SCY,G-201,G201,SCY,G 201	Others
	Salnacedin (G-201) is a small molecule compound used in the treatment of immune system disorders, skin and musculoskeletal disorders, and can be used in studies of acne vulgaris, dermatitis and psoriasis.		Others
T3510	Olumacostat Glasaretil		Acetyl-CoA Carboxylase
	Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.		Acetyl-CoA Carboxylase
T0339	Resorcinol monoacetate	Resorcin monoacetate	Others
	Resorcinol monoacetate (Resorcin monoacetate) is an antiseptic and a disinfectant, is a chemical intermediate for the production of many other pharmaceuticals, and can be used to treat acne, seborrheic dermatitis, eczema...		Others
T7370	Talarozole	R115866	Others , P450 , Retinoid Receptor , Autophagy
	Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.Talarozole for the treatment of...		Others , P450 , Retinoid Receptor , Autophagy
T21434	Sulfacetamide	NSC 63871,NSC-63871,Sebizon,Region,NSC63871,Sulphacetamide,Acetosulfamine	Others , Antibacterial , Antibiotic
	Sulfacetamide (NSC-63871) is used to treat blepharitis or conjunctivitis (in eye-drop solution) by limiting the presence of folic acid which bacteria need to survive. sulfacetamide may serve as a treatment for mild forms...		Others , Antibacterial , Antibiotic
T25048	Algestone acetophenide	Neolutin	Others
	Algestone acetophenide (Neolutin) is progesterone that used in estrus synchronization and has been evaluated as an injectable contraceptive in combination with estradiol enanthate. It is also used therapeutically as a to...		Others
T38683	SCD1 inhibitor-3	SCD1-IN-3,SCD1 inhibitor-3,SCD1 inhibitor 17a	Dehydrogenase
	SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety. SCD1 inhibitor-3 demonstrates strong potential for research in metabolic diseases, including obesit...		Dehydrogenase
T0978	Pantethine	LBF disulfide,Pantosin,Pantetina,Bis-pantethine,Pantomin,D-Pantethine	Endogenous Metabolite
	Pantethine (Pantomin) (Bis-pantethine) is a dimeric form of vitamin B5. Pantethine is less stable than pantothenic acid and tends to decompose over time if it is not kept refrigerated, so most vitamin B5 supplements are ...		Endogenous Metabolite
TN1772	Isoastilbin		Anti-infection , Tyrosinase , Antibacterial
	Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, Isoastilbin has anti-acne an...		Anti-infection , Tyrosinase , Antibacterial
T1101	Minocycline hydrochloride	Minocycline HCl	HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor...		HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
T77600	Methyl-4-oxoretinoate		Apoptosis
	Methyl-4-oxoretinoate is a synthetic retinoid compound with anticancer compounds that can induce differentiation and apoptosis in cancer cells.Methyl-4-oxoretinoate is used in the treatment of acne, psoriasis, and other ...		Apoptosis