a-b and -a chains

Expression system: E. coli
Length: 1-192, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 193-510, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1-469, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 655-1213, Partial
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 401-693, Partial
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 34-287, Partial
Activity: Not Tested

Alpha-2-HS-glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signaling in osteoblastic cells.

Carboxypeptidase A1 (CPA1) is secreted as a pancreatic peptidase that comes from the precursor form of inactive procarboxypeptidase. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. It has a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 cleaves the C-terminal amide or ester bond of peptides and involves in zymogen inhibition. Three different forms of human pancreatic procarboxypeptidase A have been isolated. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and or associated to one or two functionally different proteins, such as zymogen E.

Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two transferrin-like domains. Lactotransferrin can be cleaved into the following four chains: Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, and Lactoferroxin-C. Lactoferroxin A, Lactoferroxin B, and Lactoferroxin C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while Lactoferroxin B and Lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. LTF has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses.

As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ( crystallizable fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity.

Expression system: HEK293 Cells
Length: 2-107, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 99-326, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-106, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 20-728, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 2-147, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 23­124, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 31-96&49-162 (mutation), Full Length of Mature Protein
Activity: Cells Activity

Expression system: HEK293 Cells
Length: 31-96&49-162 (mutation), Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-139, Full Length
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 1-342, Full Length
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 1-253, Full Length
Activity: Not Tested