Search Result

Search Results for " vegfr1 "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T21593	AAL-993		VEGFR
	AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogeni...		VEGFR
T35570	Chiauranib	CS2164	c-Fms , VEGFR , FLT , PDGFR , c-Kit , Aurora Kinase
	Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-...		c-Fms , VEGFR , FLT , PDGFR , c-Kit , Aurora Kinase
T6479	Dovitinib lactate hydrate	Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258	VEGFR , FGFR , FLT , PDGFR , c-Kit
	Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) R...		VEGFR , FGFR , FLT , PDGFR , c-Kit
T4349	Sitravatinib	MG516,MGCD516	Discoidin Domain Receptor (DDR) , VEGFR , FLT , Trk receptor , TAM Receptor , c-Kit , Ephrin Receptor
	Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and Axl.
T1754	ZM 306416	CB 676475	VEGFR , Bcr-Abl , Src
	ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).		VEGFR , Bcr-Abl , Src
T15185	Lucitanib	E-3810	VEGFR , FGFR
	Lucitanib (E-3810) is a novel VEGFR and FGFR inhibitor. It potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 (IC50s: 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively).		VEGFR , FGFR
T6137	KRN-633	KRN633	VEGFR
	KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633(KRN633) for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.		VEGFR
T7945	SU14813		VEGFR , PDGFR , c-Kit
	SU14813 is a multi-receptor tyrosine kinase inhibitor with potent antiangiogenesis and antitumor activity (IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT).		VEGFR , PDGFR , c-Kit
T10157	Regorafénib N-oxyde (M2)		Raf , VEGFR , c-RET , PDGFR , c-Kit , Drug Metabolite
	Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM).		Raf , VEGFR , c-RET , PDGFR , c-Kit , Drug Metabolite
T16975	TAK-593		VEGFR , PDGFR
	TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).		VEGFR , PDGFR
T1792L	Regorafenib monohydrate		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
	Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respect...		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
T1452	Axitinib	AG-013736	VEGFR , PDGFR , c-Kit
	Axitinib (AG-013736) is an orally bioavailable tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.7, 1.6 nM for VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ, respectively.		VEGFR , PDGFR , c-Kit
T5001	Nintedanib esylate	Intedanib,BIBF 1120 (esylate),Nintedanib Ethanesulfonate Salt,BIBF 1120	VEGFR , FGFR , PDGFR
	Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β		VEGFR , FGFR , PDGFR
T6720	Vatalanib dihydrochloride	CGP-797870 dihydrochloride,ZK-222584 dihydrochloride,Vatalanib 2HCl,PTK787 dihydrochloride,Vatalanib (PTK787) 2HCl,CGP-79787 dihydrochloride	Apoptosis , VEGFR , PDGFR
	Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fold against VEGFR3/Flt-4.		Apoptosis , VEGFR , PDGFR
T6930	Pazopanib Hydrochloride	GW786034,Pazopanib HCl,GW786034 HCl,Votrient HCl,Armala	c-Fms , VEGFR , FGFR , PDGFR , c-Kit , Autophagy
	Pazopanib Hydrochloride (Votrient HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, resp...		c-Fms , VEGFR , FGFR , PDGFR , c-Kit , Autophagy
T6289	Dovitinib	TKI258,CHIR-258	VEGFR , FGFR , FLT , PDGFR , c-Kit
	Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to E...		VEGFR , FGFR , FLT , PDGFR , c-Kit
T0520	Lenvatinib	E7080	VEGFR , FGFR , c-RET , PDGFR , c-Kit
	Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib has the strongest inhibitory activity on VEGFR2 and VEGFR3 (...		VEGFR , FGFR , c-RET , PDGFR , c-Kit
T8541	Lenvatinib mesylate	E7080 (mesylate)	VEGFR , FGFR , c-RET , PDGFR , c-Kit
	Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.		VEGFR , FGFR , c-RET , PDGFR , c-Kit
T1777	Nintedanib	BIBF 1120,Intedanib	VEGFR , FGFR , FLT , PDGFR , Src
	Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRα, and PDGFRβ (IC50=59/65 nM). Nintedanib has an...		VEGFR , FGFR , FLT , PDGFR , Src
T1792	Regorafenib	BAY 73-4506,Fluoro-Sorafenib	Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
	Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally active. Regorafenib has antitumor and anti-angiogenic activity.		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
T4075	Sulfatinib	KDR-IN-1	VEGFR , FGFR , HER
	Sulfatinib (KDR-IN-1) (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC 50 s ranging from 1 to 24 nM.		VEGFR , FGFR , HER
T2288L	Motesanib Diphosphate	Motesanib,AMG 706	VEGFR , c-Kit
	Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity.		VEGFR , c-Kit
T2288	Motesanib	AMG 706	VEGFR , c-Kit
	Motesanib (AMG 706) is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-deriv...		VEGFR , c-Kit
T7104	Dovitinib lactate	CHIR-258 lactate,TKI-258 lactate	VEGFR , FGFR , FLT , PDGFR , c-Kit
	Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).		VEGFR , FGFR , FLT , PDGFR , c-Kit
T2576	Brivanib (alaninate)	BMS-582664,Brivanib Alaninate	VEGFR , FGFR , Autophagy
	Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosi...		VEGFR , FGFR , Autophagy
T8402	Regorafenib Hydrochloride	BAY73-4506 hydrochloride	Raf , VEGFR , c-RET , PDGFR , Autophagy
	Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity		Raf , VEGFR , c-RET , PDGFR , Autophagy
T0097L	Pazopanib	GW786034	VEGFR , FGFR , PDGFR , c-Kit , Autophagy
	Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result i...		VEGFR , FGFR , PDGFR , c-Kit , Autophagy
T3211	Midostaurin	N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251	Others , PKC
	PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...		Others , PKC
TQ0080	SU14813 maleate		VEGFR , PDGFR , c-Kit
	SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).		VEGFR , PDGFR , c-Kit
T13157L	TG 100801 Hydrochloride		VEGFR
	TG 100801 Hydrochloride is a prodrug to treat age-related macular degeneration. TG 100572 is a inhibitor of multi-targeted kinase(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 for VEGFR1, VEGFR2, FGFR1, FGFR2, PD...		VEGFR
T74020	O-Demethyl Lenvatinib
	O-Demethyl Lenvatinib, a metabolite of Lenvatinib (E7080), is an orally administered, multi-targeted tyrosine kinase inhibitor. It effectively inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, demonstrating significant an...
T13156	TG 100572		VEGFR
	TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck,...		VEGFR
T68539	CEP-11981	BOL 303213X,ESK981 ; BOL 303213X,ESK981
	CEP-11981 (ESK981; BOL 303213X) is an orally active tyrosine kinase inhibitor (TKI) that targets TIE2, VEGFR1-3, and FGFR1. It exhibits potential anti-tumor and anti-angiogenic effects.
T13156L	TG 100572 Hydrochloride		VEGFR , FGFR , PDGFR , Src
	TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, ...		VEGFR , FGFR , PDGFR , Src
T74021	O-Demethyl Lenvatinib hydrochloride
	O-Demethyl Lenvatinib hydrochloride, a metabolite of Lenvatinib (E7080), is an orally administered multi-targeted tyrosine kinase inhibitor. It targets and inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, demonstrating p...
T68528	M-COPA
	M-COPA is a golgi disruptor which inhibits cell surface expression of MET protein and the ADP-ribosylation factor 1 (Arf1) activation. M-COPA also inhibits angiogenesis through suppression of both VEGFR1/2 and nuclear fa...
T12925	Sitravatinib malate	MGCD516 malate,MG-516 malate	TAM Receptor
	Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT...		TAM Receptor
T2656	Fruquintinib	HMPL-013	VEGFR
	Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities.		VEGFR
T6193	Dovitinib Dilactic Acid	Dovitinib (TKI-258) Dilactic Acid,TKI258 Dilactic acid	VEGFR , FGFR , FLT , c-Kit
	Dovitinib Dilactic Acid (Dovitinib (TKI-258) Dilactic Acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FG...		VEGFR , FGFR , FLT , c-Kit
T64090	Regorafenib mesylate
	Regorafenib (BAY 73-4506) mesylate is an orally active multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1/2/3 (IC50=13/4.2/46 nM), PDGFRβ (IC50: 22 nM), Kit (IC50: 7 nM), RET (IC50: 1.5 nM) and Raf-1 (I...
T77646	Multi-kinase-IN-5
	Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that shows significant inhibition against a range of protein kinases including RET, KIT, cMet, VEGFR1, VEGFR2, FGFR1, PDGFR, and BRAF, with correspondin...
T62788	Pexidartinib hydrochloride
	Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, selective, orally active, ATP-competitive inhibitor of colony-stimulating factor 1 (CSF1R or M-CSFR) (IC50: 20 nM) and c-Kit (IC50: 10 nM). Pexidartinib hy...
T2456	Tivozanib	AV-951,KRN951	VEGFR , PDGFR , Ephrin Receptor
	Tivozanib (KRN951) is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities.		VEGFR , PDGFR , Ephrin Receptor
T3463	NVP-ACC789	ACC-789,ZK202650	VEGFR , PDGFR
	ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.		VEGFR , PDGFR
T13157	TG 100801	TG100801,TG 100572	VEGFR , Src
	TG 100801 is a dual inhibitor of VEGFr2 and Src family (Src and YES) kinases and is a candidate compound for the treatment of age-related macular degeneration (AMD).		VEGFR , Src
T7611	ODM-203		VEGFR , FGFR
	ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity		VEGFR , FGFR
T83911	CYY292
	CYY292 is a chemical compound acting as an inhibitor of PDGFRα, PDGFRβ, FGFR1, -2, and -3, with respective IC50 values of 5.35, 4.6, 28, 28, and 78 nM. It exhibits selectivity over FGFR4 (IC50 > 1,000 nM) while also targ...
TQ0059	Ilorasertib	ABT-348	VEGFR , FLT , c-RET , PDGFR , Aurora Kinase
	Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: ...		VEGFR , FLT , c-RET , PDGFR , Aurora Kinase
TQ0313	NVP-BAG956	BAG956	PI3K
	NVP-BAG956 is an ATP-competitive PI3K inhibitor (IC50s: 34/56/112/444 nM for PI3Kδ/PI3Kα/PI3Kγ/PI3Kβ).		PI3K
T11638	Ilorasertib hydrochloride	ABT-348 hydrochloride	Aurora Kinase
	Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s: 1 nM, 7 nM, 120 nM). It also suppresses RET tyrosine kinase,...		Aurora Kinase

Compounds

Target: c-Fms, VEGFR, FLT, PDGFR, c-Kit, Aurora Kinase

Dovitinib lactate hydrate

T6479

Synonym: Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258

Target: VEGFR, FGFR, FLT, PDGFR, c-Kit

Sitravatinib

T4349

Synonym: MG516,MGCD516

Target: Discoidin Domain Receptor (DDR), VEGFR, FLT, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor

ZM 306416

T1754

Synonym: CB 676475

Target: VEGFR, Bcr-Abl, Src

Lucitanib

T15185

Synonym: E-3810

Target: VEGFR, FGFR

Target: VEGFR, PDGFR, c-Kit

Regorafénib N-oxyde (M2)

T10157

Synonym:

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Drug Metabolite

TAK-593

T16975

Synonym:

Target: VEGFR, PDGFR

Regorafenib monohydrate

T1792L

Synonym:

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy

Axitinib

T1452

Synonym: AG-013736

Target: VEGFR, PDGFR, c-Kit

Nintedanib esylate

T5001

Synonym: Intedanib,BIBF 1120 (esylate),Nintedanib Ethanesulfonate Salt,BIBF 1120

Target: VEGFR, FGFR, PDGFR

Vatalanib dihydrochloride

T6720

Synonym: CGP-797870 dihydrochloride,ZK-222584 dihydrochloride,Vatalanib 2HCl,PTK787 dihydrochloride,Vatalanib (PTK787) 2HCl,CGP-79787 dihydrochloride

Target: Apoptosis, VEGFR, PDGFR

Pazopanib Hydrochloride

T6930

Synonym: GW786034,Pazopanib HCl,GW786034 HCl,Votrient HCl,Armala

Target: c-Fms, VEGFR, FGFR, PDGFR, c-Kit, Autophagy

Dovitinib

T6289

Synonym: TKI258,CHIR-258

Target: VEGFR, FGFR, FLT, PDGFR, c-Kit

Lenvatinib

T0520

Synonym: E7080

Target: VEGFR, FGFR, c-RET, PDGFR, c-Kit

Lenvatinib mesylate

T8541

Synonym: E7080 (mesylate)

Target: VEGFR, FGFR, c-RET, PDGFR, c-Kit

Nintedanib

T1777

Synonym: BIBF 1120,Intedanib

Target: VEGFR, FGFR, FLT, PDGFR, Src

Regorafenib

T1792

Synonym: BAY 73-4506,Fluoro-Sorafenib

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy

Sulfatinib

T4075

Synonym: KDR-IN-1

Target: VEGFR, FGFR, HER

Motesanib Diphosphate

T2288L

Synonym: Motesanib,AMG 706

Target: VEGFR, c-Kit

Motesanib

T2288

Synonym: AMG 706

Target: VEGFR, c-Kit

Dovitinib lactate

T7104

Synonym: CHIR-258 lactate,TKI-258 lactate

Target: VEGFR, FGFR, FLT, PDGFR, c-Kit

Brivanib (alaninate)

T2576

Synonym: BMS-582664,Brivanib Alaninate

Target: VEGFR, FGFR, Autophagy

Regorafenib Hydrochloride

T8402

Synonym: BAY73-4506 hydrochloride

Target: Raf, VEGFR, c-RET, PDGFR, Autophagy

Pazopanib

T0097L

Synonym: GW786034

Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy

Midostaurin

T3211

Synonym: N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251

Target: VEGFR, PDGFR, c-Kit

TG 100801 Hydrochloride

T13157L

Synonym:

Target: VEGFR

O-Demethyl Lenvatinib

Synonym: BOL 303213X,ESK981 ; BOL 303213X,ESK981

Target:

TG 100572 Hydrochloride

T13156L

Synonym:

Target: VEGFR, FGFR, PDGFR, Src

O-Demethyl Lenvatinib hydrochloride

Synonym: MGCD516 malate,MG-516 malate

Dovitinib Dilactic Acid

T6193

Synonym: Dovitinib (TKI-258) Dilactic Acid,TKI258 Dilactic acid

Target: VEGFR, FGFR, FLT, c-Kit

Pexidartinib hydrochloride

Synonym: AV-951,KRN951

Target: VEGFR, PDGFR, Ephrin Receptor

NVP-ACC789

T3463

Synonym: ACC-789,ZK202650

Target: VEGFR, PDGFR

TG 100801

T13157

Synonym: TG100801,TG 100572

Target: VEGFR, FGFR

Target: VEGFR, FLT, c-RET, PDGFR, Aurora Kinase

Ilorasertib hydrochloride

T11638

Synonym: ABT-348 hydrochloride

Target: Aurora Kinase

Cat No.	Product Name	Synonyms	Targets
T15542	Hypothemycin		Others
	Hypothemycin is a fungal polyketide and is a multikinase inhibitor (Kis: 10/70 nM, 17/38 nM, 90 nM, 900 nM/1.5 μM, and 8.4/2.4 μM for VEGFR2/VEGFR1, MEK1/MEK2, FLT-3, PDGFRβ/PDGFRα, and ERK1/ERK2, respectively).		Others

Natural Products

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPK-00450	VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	VEGFR1 (vascular endothelial growth factor receptor 1), also called Flt-1 (Fms-like tyrosine kinase), is a 180 kDa type I transmembrane glycoprotein in the class III subfamily of receptor tyrosine kinases (RTKs).yrosine-...
TMPK-00451	VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	VEGFR1 (vascular endothelial growth factor receptor 1), also called Flt-1 (Fms-like tyrosine kinase), is a 180 kDa type I transmembrane glycoprotein in the class III subfamily of receptor tyrosine kinases (RTKs).yrosine-...
TMPY-00637	FLT1 Protein, Human, Recombinant (aa 1-328, His)	Human	HEK293
	Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-06780	FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-05733	FLT1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-02108	FLT1 Protein, Human, Recombinant (aa 1-756, His)	Human	HEK293
	Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-00119	FLT1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-06665	FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293
	Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPJ-00864	VEGF165 Protein, Human, Recombinant	Human	Human Cells
	Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator...
TMPY-01936	VEGFR3/FLT4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-00949	VEGFR3/FLT4 Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPJ-00865	VEGF121 Protein, Human, Recombinant (His)	Human	Human Cells
	Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD...
TMPH-03131	VEGFA Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	E. coli
	Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds t...
TMPJ-01145	ABCB5 Protein, Human, Recombinant (Trx)	Human	E. coli
	ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progen...
TMPY-06620	VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-01937	VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-01069	VEGFR3/FLT4 Protein, Human, Recombinant (hFc)	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...