T1526

Nifuratel (SAP 113) is a local antiprotozoal and antifungal agent that may also be given orally.

MINT1526A (RG-7594) is a humanized IgG1 monoclonal antibody inhibitor targeting α5β1 integrin, exhibiting significant anti-angiogenic activity. This compound is applicable in cancer research.

Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.

Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).

Vactosertib Hydrochloride (EW-7197 Hydrochloride) is an orally active and highly efficient ATP-competitive ALK5 (activin receptor-like kinase 5) inhibitor, a TGF-β receptor I inhibitor with anti-metastatic and anticancer properties. It sensitizes pancreatic cancer cells to gemcitabine by inhibiting their viability.

Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a R-enantiomer of Selisistat (T6111) with much less activity than Selisistat (IC50 of SIRT1 > 100 μM).

EZ-482 is an apolipoprotein (apoE) ligand that binds to the C-terminal domain of apoE3 and apoE4 through a unique N-terminal allosteric effect, useful in Alzheimer's disease research.

F16 ((E)-4-(3-indolylvinyl)-N-methylpyridinium iodide) inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.

Falecalcitriol is an analog of calcitriol. It has a higher potency both in vivo and in vitro systems, which is longer duration of action in vivo.