T1379

L-5-Hydroxytryptophan (L-5-HTP) is a naturally occurring amino acid and dietary supplement that serves as a precursor to the neurotransmitter serotonin. It can be used as an antidepressant, appetite suppressant, and sleep aid, and acts as an antagonist to reserpine. L-5-HTP is widely used in research on myoclonus, fibromyalgia, migraine, and cerebellar ataxia, and is also commonly used to induce epilepsy models.

Neridronate is an aminodiphosphate that is commonly used in diseases associated with disorders of bone metabolism and complex regional pain syndromes (CRPS) such as osteogenesis imperfecta (OI) and Paget's disease of bone (PDB).

Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.

N-Methyl Duloxetine hydrochloride elicits both tonic and use-dependent block of neuronal Na+ channels. N-Methyl Duloxetine hydrochloride is an analgesic.

Nampt-IN-3 simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC (IC50s of 31 nM and 55 nM, respectively).

Neohesperidose is a natural product isolated from species of typha.

Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase.

Nivalenol is a fungal metabolite produced by Fusarium graminearum. Nivalenol induces cell death through caspase and intrinsic apoptotic pathways thus affecting the immune system and causing emesis, growth retardation, and reproductive disorders.

Nortanshinone is a natural product isolated from Dan-Shen.

NQO1 substrate is a highly potent NQO1 substrate with potential antitumor activity for leukemia research.