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T-611 free base

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    785
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T-611 free base
T28905350595-60-7
T-611, a cytomegalovirus replication inhibitor, is used potentially for the treatment of cytomegalovirus infections.
  • $1,520
6-8 weeks
Size
QTY
GsMTx4 TFA (1209500-46-8 free base)
TP1300
GsMTx4 TFA (1209500-46-8 free base) is a spider venom peptide that selectively inhibits cation permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families.
  • $468
In Stock
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QTY
TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Tirzepatide Acetate(2023788-19-2 free base)
TP1111L
Tirzepatide (LY3298176) Acetate (2023788-19-2 free base) is a new molecule that can control blood glucose levels by combining dual agonism of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors.[3]
  • $358
In Stock
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QTY
TargetMol | Inhibitor Hot
LL-37, Human acetate(154947-66-7 free base)
TP1775L
LL-37, Human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity.
  • $118
In Stock
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QTY
TargetMol | Inhibitor Hot
CS-722 Free base
T10893749179-13-3In house
CS-722 Free base is a synthetic central muscle relaxant exhibiting muscle relaxant effects and inhibition of spinal reflexes. In hippocampal cultures, CS-722 Free base may suppress spontaneous inhibitory and excitatory post-synaptic currents by inhibiting sodium and calcium currents.
  • $117
In Stock
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TargetMol | Inhibitor Sale
AHR antagonist 5 free base
T397622247950-42-9In house
AHR antagonist 5 free base is an orally active AHR antagonist with IC50 of approximately 35-150 nM in human and rodent cell lines, and exhibits anticancer activity.
  • $155
In Stock
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QTY
EAD1 TFA(1644388-26-0 Free base)
T35329L2320427-95-8In house
EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL also induces apoptosis
  • $58
In Stock
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Quilseconazole Formic acid(1340593-70-5 Free base)
T16704L In house
Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.
  • $169
In Stock
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TargetMol | Inhibitor Sale
Nemazoline Free Base
T71012130759-56-7In house
Nemazoline Free Base acts as an α1-adrenergic agonist and an α2-adrenergic antagonist, and may be used in the treatment of trace amine-associated receptor-related disorders.
  • $293 TargetMol
In Stock
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ADR-851 free base
T23642138559-56-5In house
ADR-851 free base (ADR 851 free base) is a 5-HT3 receptor antagonist and a novel antiemetic with analgesic activity.
  • $293 TargetMol
In Stock
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KB-5492 free base
T62396113594-64-2In house
KB-5492 free base is an orally available and selective antiulcer agent that inhibits sigma receptors, inhibits [3H]1,3-di(2-tolyl)guanidine (DTG) binding to sigma receptors, and may be useful in the study of gastric lesions and gastric secretion.
  • $35 TargetMol
In Stock
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RPR107393 free base
T12765197576-78-6In house
RPR107393 free base is a selective inhibitor of squalene synthase [rat liver microsomal squalene synthase] with an IC50 of 0.8 nM.
  • $1,520
6-8 weeks
Size
QTY
Masupirdine free base
T11948701205-60-9In house
Masupirdine free base (SUVN-502 free base) is an orally available 5-HT6 receptor antagonist that crosses the blood-brain barrier, with a Ki value of 2.04 nM for the human 5-HT6 receptor. It is potent and selective, inhibiting multiple targets, and can be used in the study of neurological disorders such as Alzheimer's disease.
  • $293 TargetMol
In Stock
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BA 1 acetate(183241-31-8 free base)
TP1913L1
BA 1 acetate is a potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 lung cancer cell proliferation in v
  • $97
In Stock
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TargetMol | Inhibitor Sale
RFRP-1 (human) acetate(311309-25-8 free base)
TP1937L1
RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, eject
  • $133
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AS601245.2TFA (345987-15-7 free base)
T8661345987-16-8
AS601245.2TFA (345987-15-7 free base) (AS601245.2TFA) is a cell-permeable Inhibitor of JNK (IC50s of 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3, respectively).
  • $53
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CEF6 acetate(913545-15-0 free base)
TP1822L
CEF6 acetate is a HLA-B7 restricted influenza virus nucleoprotein epitope, belongs to the CEF control peptides. The CEF control peptides are 8-12 amino acids in length, with sequences derived from the human cytomegalovirus, Epstein-Barr virus and influenz
  • $56
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TargetMol | Inhibitor Sale
(Arg)9 TFA (143413-47-2 free base)
TP10792283335-13-5
(Arg)9 TFA (Peptide R9 TFA) is a cell-penetrating peptide. (Arg)9 TFA (Nona-L-arginine TFA) exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.
  • $139
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Cyclotraxin B acetate(1203586-72-4 free base)
TP2068L
Cyclotraxin B acetate is an antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold allodynia in mice. Also shown to exhibit putative anxiolytic properties in mice.
  • $173
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d[Cha4]-AVP acetate(500170-27-4 free base)
TP2082L
d[Cha4]-AVP acetate is a potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secretion and exhibits negligible vasopr
  • $100
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TargetMol | Inhibitor Sale
Kinetensin acetate(103131-69-7 free base)
TP1116L
Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide.
  • $96
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pep2-EVKI acetate(1315378-67-6 free base)
TP1943L1
Pep2-EVKI acetate is a cell-permeable peptide. Pep2-EVKI acetate interferes the interaction between protein interacting with C-kinase (PICK1) and GluR2 AMPA receptor subunits.
  • $166
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CL2A-SN-38 DCA 1279680-68-0(free base)
T17731L
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a noncleavable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. .
  • $133
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Guan-fu base A hydrochloride(1394-48-5 free base)
T8182L618094-85-2
Guan-fu base A hydrochloride is an antiarrhythmic alkaloid was isolated from Aconitum coreanum. Guanfu base A is hydrochloride a CYP2D6 inhibitor of human, monkey, and dog isoforms.
  • $133
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Nonapeptide-1 acetate salt (158563-45-2 free base)
TP1101
Nonapeptide-1 acetate salt (158563-45-2 free base) (Melanostatine-5 acetate salt) , a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Nonapeptide-1 acetate salt (158563-45-2 free base) , a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM.
  • $63
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Eledoisin trifluoroacetate (69-25-0 free base)
T883210129-92-7
Eledoisin trifluoroacetate (69-25-0 free base) is a peptide extracted from the posterior salivary glands of certain small octopi (Eledone spp., Mollusca), or obtained by synthesis. Its actions resemble those of SUBSTANCE P; it is a potent vasodilator and increases capillary permeability.
  • $133
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HS 014 acetate(207678-81-7 free base)
TP2015L
HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake in rats and nociception in mice following central
  • $185
In Stock
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TargetMol | Inhibitor Sale
CEP-28122 mesylate salt (1022958-60-6 free base)
T10759
CEP-28122 mesylate salt (1022958-60-6 free base) is a highly selective orally active ALK inhibitor (IC50: 1.9 nM in an enzyme-based TRF assay).
  • $39
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Urotensin II, mouse acetate (9047-55-6 free base)
TP2165
Urotensin II, mouse acetate (9047-55-6 free base) is an endogenous ligand for the orphan GPR14 or SENR. It is a potent vasoconstrictor.
  • $101
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Adrenorphin 3TFA(88377-68-8(free base))
T7567L
Adrenorphin 3TFA(88377-68-8(free base)) (Metorphamide) is an agonist of μ-opioid receptor(Ki :12 nM).
  • $41
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Autocamtide 2 TFA(129198-88-5 free base)
TP1217L
Autocamtide 2 TFA is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). Autocamtide 2 TFA can be used in the CaMKII activity assay.
  • $52
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Matrixyl Acetate(214047-00-4 free base)
T21250L
Matrixyl Acetate(214047-00-4 free base) (Palmitoyl pentapeptide) is a matrikine used in anti-wrinkle cosmetics.
  • $29
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CEF3 acetate(199727-62-3 free base)
TP1782L
CEF3 acetate corresponds to aa 13-21 of the influenza A virus M1 protein. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life cycle.
  • $76
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PKG Substrate acetate(81187-14-6 free base)
TP1787L
PKG Substrate acetate is a selective substrate for cGMP-dependent protein kinase (PKG).PKG Substrate is a selective substrate for protein kinase G (PKG) with a strong preference for PKG Iα (Km = 59 μM) over PKG II (Km = 305 μM).
  • $61
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Iα52 acetate(137756-45-7 free base)
TP1600L
Iα52 acetate is a naturally processed peptide encompassed the residues 52-68 of the murine I-Eα chain and may contribute to selection of immature T cells.
  • $80
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JAG-1, scrambled TFA(402941-23-5 free base
TP1686L
JAG-1, scrambled TFA is a scrambled sequence of JAG-1(188-204).
  • $56
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gamma-DGG acetate(6729-55-1 free base)
T15369L2935387-13-4
gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.
  • $29
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Speract TFA(76901-59-2(free base))
T7487L
Speract TFA is a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.
  • $40
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Xenopsin 2TFA(51827-01-1(free base)
T7615L
Xenopsin(2TFA) is a neurotensin-like octapeptide previously isolated from amphibian skin.
  • $41
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Hemopressin (rat) acetate(568588-77-2 free base)
TP1901L1
Hemopressin (rat) acetate is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin is orally active, selective and inverse agonist of CB2 cannabinoid receptors. Hemopressin exerts antinocicep
  • $247
In Stock
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Dynorphin A acetate(80448-90-4 free base)
TP2040L
Dynorphin A acetate is an Endogenous kappa receptor agonist.
  • $65
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Dynorphin A 1-10 acetate(79994-24-4 free base)
TP1813L
Dynorphin A (1-10) acetate is an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A (1-10) also blocks NMDA-activated current with an IC50 of 42.0 μM.
  • $101
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Arg-Gly-Glu-Ser acetate(93674-97-6 free base)
TP1458L
Arg-Gly-Glu-Ser acetate is a RGD related peptide that is a control for the RGDS activity of fibrinogen binding to activated platelets.
  • $35
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MRT67307 HCl (1190378-57-4(free base))
T5162
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).
  • $30
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TargetMol | Citations Cited
FMRF acetate(74012-06-9 free base)
TP1784L
FMRF acetate is a peptide consisting of 4 amino acid residues.
  • $37
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VCH-916 free acid(1200133-34-1 free base)
TQ0122L914778-92-0
VCH-916 is a novel nonnucleoside HCV NS5B polymerase inhibitor.
  • $41
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JNJ-63576253 free base
T89332110426-27-0
JNJ-63576253 free base (TRC253) is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC).
  • $34
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LUN42518 HCl 47142-51-8(free base)
T8738
LUN42518 HCl is an analogue of phentolamine. Phentolamine is a nonselective alpha-adrenergic antagonist.
  • $80
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