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Search Results for " slc6a4 "

Targets

34

Compounds

3

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T12232 Nitroxazepine CIBA 2330Go Serotonin Transporter
Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the research of depression
T8708 Paroxetine Serotonin Transporter
Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.
T0450 Fluoxetine LY-110140 5-HT Receptor , Serotonin Transporter , MRP , Autophagy
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity.
T7061 Duloxetine Serotonin Transporter
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.
T22714 Decynium 22 Others
Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitor
T22453 Venlafaxine Wy 45030 Serotonin Transporter
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.
T2594 Dextromilnacipran Levomilnacipran Serotonin Transporter , Norepinephrine
Dextromilnacipran (Levomilnacipran) is a selective serotonin and norepinephrine reuptake inhibitor.
T1189 Milnacipran hydrochloride Milnacipran HCl,Savella,Dalcipran Serotonin Transporter , Norepinephrine
Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Milnacipran hydrochloride is an enantiomer of milnacipran, which is used to treat fibromy...
T10758L Centanafadine hydrochloride EB-1020 hydrochloride Dopamine Receptor , Serotonin Transporter , Adrenergic Receptor , Norepinephrine
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin...
T11087 DOV-216,303 Free Base DOV-216303 Dopamine Receptor , Serotonin Transporter , Norepinephrine
DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base exhibits antidepressant effects.
T7940 Milnacipran ((1S-cis) hydrochloride) Levomilnacipran Hydrochloride Serotonin Transporter
Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia.
T2395 Vortioxetine Lu AA 21004 5-HT Receptor , Serotonin Transporter
Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment.
T1580 Desvenlafaxine WY 45233 Succinate,O-Desmethylvenlafaxine 5-HT Receptor , Serotonin Transporter , Norepinephrine
Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive age...
T0450L Fluoxetine hydrochloride Fluoxetine HCl,LY-110140,Lilly110140 5-HT Receptor , Serotonin Transporter , Autophagy
Fluoxetine hydrochloride (Lilly110140) is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
T0472 Venlafaxine hydrochloride Venlafaxine HCl,Wy 45030 hydrochloride 5-HT Receptor , Serotonin Transporter
Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a cyclohexanol and phenylethylamine derivative that functions as a SEROTONIN AND NORADRENALINE REUPTAKE INHIBITOR (SNRI) and is used as an ANTIDEPRESSIVE AGENT.
T0482 Sertraline hydrochloride Sertraline HCl,CP-51974-1 HCl 5-HT Receptor , Serotonin Transporter
Sertraline hydrochloride (Sertraline HCl) is a selective serotonin uptake inhibitor that is used in the treatment of depression.
T6232 Vilazodone Hydrochloride SB659746A,EMD 68843,Vilazodone HCl Others , 5-HT Receptor , Serotonin Transporter
Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the major depressive disorder.
T3526 Dasotraline hydrochloride SEP-225289 hydrochloride Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respe...
T1279 Vilazodone SB659746A,EMD 68843 5-HT Receptor , Serotonin Transporter
Vilazodone (SB659746A) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety activities. Vilazodone inhibits the reuptake of serotonin from...
T7941 Imipramine hydrochloride Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine Serotonin Transporter
Imipramine hydrochloride (Imipramine HCl) is a first generation tricyclic antidepressant that acts primarily as an inhibitor of serotonin and norepinephrine transporters (Kds = 1.4 and 37 nM, respectively).Imipramine hyd...
T6493 Escitalopram Oxalate Cipralex,(S)-(+)Citalopram oxalate Others , 5-HT Receptor , Serotonin Transporter
Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
T1636 Paroxetine hydrochloride Paroxetine HCl,BRL29060 hydrochloride,FG-7051,BRL29060A 5-HT Receptor , Serotonin Transporter , GRK , AChR , Autophagy
Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.
T0255 Clomipramine hydrochloride Clomipramine HCl,Anafranil Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine , GST
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demeth...
T21013 Clomipramine Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina 5-HT Receptor
Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of su...
T1077 Fluvoxamine maleate MK-264,DU-23000 (maleate) 5-HT Receptor , Serotonin Transporter
Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders.
T2092 Amitifadine hydrochloride DOV-21947 hydrochloride,EB-1010 hydrochloride Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
T6188 Desvenlafaxine succinate hydrate O-Desmethylvenlafaxine succinate hydrate,WY 45233 Succinate,Desvenlafaxine Succinate 5-HT Receptor , Serotonin Transporter , Norepinephrine
Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
T6461 Dapoxetine hydrochloride LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy 5-HT Receptor , Serotonin Transporter
Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.
T0991 Desipramine hydrochloride NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020 Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-upt...
T1471 Duloxetine hydrochloride Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and i...
T1483 Citalopram hydrobromide Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,Citalopram HBr 5-HT Receptor , Serotonin Transporter , Autophagy
Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system...
T0678 Amitriptyline hydrochloride Amitriptyline HCl,Tryptizol,Domical,Annoyltin Trk receptor , Sigma receptor , 5-HT Receptor , Serotonin Transporter , Sodium Channel , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor
Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
T2395L Vortioxetine hydrobromide Vortioxetine (Lu AA21004) HBr,Vortioxetine HBr,Lu AA21004 hydrobromide 5-HT Receptor , Serotonin Transporter
Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33/3.7/19/1.6 nM).
T0039 Dapoxetine Dapoxetina,Dapoxetinum Others , 5-HT Receptor
Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.

Compounds

Nitroxazepine
T12232
Synonym: CIBA 2330Go
Target: Serotonin Transporter
Paroxetine
T8708
Synonym:
Target: Serotonin Transporter
Fluoxetine
T0450
Synonym: LY-110140
Target: 5-HT Receptor, Serotonin Transporter, MRP, Autophagy
Duloxetine
T7061
Synonym:
Target: Serotonin Transporter
Decynium 22
T22714
Synonym:
Target: Others
Venlafaxine
T22453
Synonym: Wy 45030
Target: Serotonin Transporter
Dextromilnacipran
T2594
Synonym: Levomilnacipran
Target: Serotonin Transporter, Norepinephrine
Milnacipran hydrochloride
T1189
Synonym: Milnacipran HCl,Savella,Dalcipran
Target: Serotonin Transporter, Norepinephrine
Centanafadine hydrochloride
T10758L
Synonym: EB-1020 hydrochloride
Target: Dopamine Receptor, Serotonin Transporter, Adrenergic Receptor, Norepinephrine
DOV-216,303 Free Base
T11087
Synonym: DOV-216303
Target: Dopamine Receptor, Serotonin Transporter, Norepinephrine
Milnacipran ((1S-cis) hydrochloride)
T7940
Synonym: Levomilnacipran Hydrochloride
Target: Serotonin Transporter
Vortioxetine
T2395
Synonym: Lu AA 21004
Target: 5-HT Receptor, Serotonin Transporter
Desvenlafaxine
T1580
Synonym: WY 45233 Succinate,O-Desmethylvenlafaxine
Target: 5-HT Receptor, Serotonin Transporter, Norepinephrine
Fluoxetine hydrochloride
T0450L
Synonym: Fluoxetine HCl,LY-110140,Lilly110140
Target: 5-HT Receptor, Serotonin Transporter, Autophagy
Venlafaxine hydrochloride
T0472
Synonym: Venlafaxine HCl,Wy 45030 hydrochloride
Target: 5-HT Receptor, Serotonin Transporter
Sertraline hydrochloride
T0482
Synonym: Sertraline HCl,CP-51974-1 HCl
Target: 5-HT Receptor, Serotonin Transporter
Vilazodone Hydrochloride
T6232
Synonym: SB659746A,EMD 68843,Vilazodone HCl
Target: Others, 5-HT Receptor, Serotonin Transporter
Dasotraline hydrochloride
T3526
Synonym: SEP-225289 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
Vilazodone
T1279
Synonym: SB659746A,EMD 68843
Target: 5-HT Receptor, Serotonin Transporter
Imipramine hydrochloride
T7941
Synonym: Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine
Target: Serotonin Transporter
Escitalopram Oxalate
T6493
Synonym: Cipralex,(S)-(+)Citalopram oxalate
Target: Others, 5-HT Receptor, Serotonin Transporter
Paroxetine hydrochloride
T1636
Synonym: Paroxetine HCl,BRL29060 hydrochloride,FG-7051,BRL29060A
Target: 5-HT Receptor, Serotonin Transporter, GRK, AChR, Autophagy
Clomipramine hydrochloride
T0255
Synonym: Clomipramine HCl,Anafranil
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine, GST
Clomipramine
T21013
Synonym: Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina
Target: 5-HT Receptor
Fluvoxamine maleate
T1077
Synonym: MK-264,DU-23000 (maleate)
Target: 5-HT Receptor, Serotonin Transporter
Amitifadine hydrochloride
T2092
Synonym: DOV-21947 hydrochloride,EB-1010 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
Desvenlafaxine succinate hydrate
T6188
Synonym: O-Desmethylvenlafaxine succinate hydrate,WY 45233 Succinate,Desvenlafaxine Succinate
Target: 5-HT Receptor, Serotonin Transporter, Norepinephrine
Dapoxetine hydrochloride
T6461
Synonym: LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy
Target: 5-HT Receptor, Serotonin Transporter
Desipramine hydrochloride
T0991
Synonym: NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor
Duloxetine hydrochloride
T1471
Synonym: Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
Citalopram hydrobromide
T1483
Synonym: Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,Citalopram HBr
Target: 5-HT Receptor, Serotonin Transporter, Autophagy
Amitriptyline hydrochloride
T0678
Synonym: Amitriptyline HCl,Tryptizol,Domical,Annoyltin
Target: Trk receptor, Sigma receptor, 5-HT Receptor, Serotonin Transporter, Sodium Channel, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor
Vortioxetine hydrobromide
T2395L
Synonym: Vortioxetine (Lu AA21004) HBr,Vortioxetine HBr,Lu AA21004 hydrobromide
Target: 5-HT Receptor, Serotonin Transporter
Dapoxetine
T0039
Synonym: Dapoxetina,Dapoxetinum
Target: Others, 5-HT Receptor
Cat No. Product Name Synonyms Targets
T7521 Azaphen Pipofezin hydrochloride,Pipofezine hydrochloride,Azafen 5-HT Receptor , Serotonin Transporter
Azaphen (Pipofezin hydrochloride) is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity.
T1317 Cinchonidine α-Quinidine,L-Cinchonidine 5-HT Receptor , Serotonin Transporter , Parasite
Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.
T0185 Escitalopram Seroplex,S-(+)-Citalopram,(S)-Citalopram Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patien...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-03274 ATF-4 Protein, Rat, Recombinant (His & Myc) Rat E. coli
Transcription factor that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') and displays two biological functions, as regulator of metabolic and redox processes under normal cellular conditions, an...
TargetMol