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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T33945 | PF-06260933 HCl | PF06260933 dihydrochloride,PF-06260933 dihydrochloride,PF 06260933 dihydrochloride | Others |
PF-06260933 Dihydrochloride is a MAP4K4 (HGK) inhibitor (IC50 = 140 nM). It can improve the fasting hyperglycemia in mice. In addition, it inhibited Mink and Tnik (IC50 values of 8 and 13 nM, respectively). | |||
T4221 | PF-06260933 | PF-6260933,PF 6260933,PF6260933 | MAPK |
PF-06260933 is a highly selective small-molecule MAP4K4 inhibitor with IC50s of 3.7 and 160 nM for kinase and cell, respectively. |