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Cat No. | Product Name | Synonyms | Targets |
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T24271 | KSP-IA | KSP IA | |
KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor. | |||
T32571 | Larkspur alkaloid | Bicoloridine | |
Larkspur alkaloid is a bioactive chemical. | |||
T39014 | KSPWFTTL | ||
KSPWFTTL is an immunodominant epitope derived from the p15E transmembrane protein. It is Kb-restricted and can enhance the susceptibility of a tumor cell line to cytotoxic T lymphocytes targeting anti-AKR/Gross MuLV. | |||
TQ0318 | Filanesib | ARRY-520,ARRY 520 | KSP |
Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity. | |||
T2255 | SB-743921 hydrochloride | SB743921 HCl,SB743921 | Kinesin , KSP |
SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM). | |||
T6209 | CW-069 | CW069 | Kinesin , Microtubule Associated |
CW-069 (IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP. | |||
T2103 | Ispinesib | CK0238273,SB-715992 | Apoptosis , Kinesin , KSP |
Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic properties. | |||
TQ0318L | ARRY 520 hydrochloride | KSP | |
ARRY 520 hydrochloride is a kinesin spindle protein (KSP) inhibitor.ARRY 520 hydrochloride induces cell death by apoptosis and has potent anti-proliferative activity. | |||
T25418 | Filanesib TFA | Filanesib trifluoroacetic acid,ARRY-520 TFA,ARRY 520 TFA,ARRY520 TFA | |
Filanesib (ARRY-520) targets the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, in... | |||
T21321 | MK-0731 | ||
MK-0731, a synthetic small molecule with potential antineoplastic activity, selectively inhibits kinesin spindle protein (KSP), leading to the inhibition of mitotic spindle assembly, induction of cell cycle arrest during... | |||
T68743 | AZD4877 HCl | ||
AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activity. KSP inhibitor AZD4877 selectively inhibits microtubule motor protein KSP (also called kinesin-5 or Eg5), which may re... | |||
T69415 | CK0106023 | ||
CK0106023 was specific inhibitor of KSP. In tumor-bearing mice, CK0106023 exhibited antitumor activity comparable to or exceeding that of paclitaxel and caused the formation of monopolar mitotic figures identical to thos... | |||
T36816 | S-trityl-L-Cysteine | STLC | Kinesin |
S-trityl-L-Cysteine is a non-natural amino acid and an inhibitor of Eg5, also known as KSP and Kif11, a mitotic kinesin necessary for mitotic spindle formation. S-trityl-L-Cysteine inhibits the ATPase activity of Eg5 in ... | |||
T28694 | SB-743921 free base | SB743921,SB-921,SB921,SB-743921,GSK-743921,GSK-921 | |
SB-743921, a kinesin spindle protein (KSP) inhibitor, is used potentially for the treatment of non-Hodgkin's lymphoma (NHL). | |||
T10373 | (R)-Filanesib | (R)-ARRY-520 | Others |
(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM). | |||
T81871 | Mal-PEG8-Val-Ala-PAB-SB-743921 | ||
Compound D7, also known as Mal-PEG8-Val-Ala-PAB-SB-743921, is a drug-linker conjugate for antibody-drug conjugates (ADC). It comprises the KSP inhibitor SB-743921 connected through a linker and is utilized in the synthes... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05473 | KSP37/FGFBP2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
TMPY-01763 | Cadherin 16/CDH16 Protein, Human, Recombinant (His) | Human | HEK293 |
KSP-Cadherin/Cadherin-16 is a member of the cadherin superfamily, calcium-dependent, membrane-associated glycoproteins. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane regio... |