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Search Results for " ksp "

Targets

16

Compounds

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T24271 KSP-IA KSP IA
KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.
T32571 Larkspur alkaloid Bicoloridine
Larkspur alkaloid is a bioactive chemical.
T39014 KSPWFTTL
KSPWFTTL is an immunodominant epitope derived from the p15E transmembrane protein. It is Kb-restricted and can enhance the susceptibility of a tumor cell line to cytotoxic T lymphocytes targeting anti-AKR/Gross MuLV.
TQ0318 Filanesib ARRY-520,ARRY 520 KSP
Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.
T2255 SB-743921 hydrochloride SB743921 HCl,SB743921 Kinesin , KSP
SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).
T6209 CW-069 CW069 Kinesin , Microtubule Associated
CW-069 (IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.
T2103 Ispinesib CK0238273,SB-715992 Apoptosis , Kinesin , KSP
Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic properties.
TQ0318L ARRY 520 hydrochloride KSP
ARRY 520 hydrochloride is a kinesin spindle protein (KSP) inhibitor.ARRY 520 hydrochloride induces cell death by apoptosis and has potent anti-proliferative activity.
T25418 Filanesib TFA Filanesib trifluoroacetic acid,ARRY-520 TFA,ARRY 520 TFA,ARRY520 TFA
Filanesib (ARRY-520) targets the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, in...
T21321 MK-0731
MK-0731, a synthetic small molecule with potential antineoplastic activity, selectively inhibits kinesin spindle protein (KSP), leading to the inhibition of mitotic spindle assembly, induction of cell cycle arrest during...
T68743 AZD4877 HCl
AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activity. KSP inhibitor AZD4877 selectively inhibits microtubule motor protein KSP (also called kinesin-5 or Eg5), which may re...
T69415 CK0106023
CK0106023 was specific inhibitor of KSP. In tumor-bearing mice, CK0106023 exhibited antitumor activity comparable to or exceeding that of paclitaxel and caused the formation of monopolar mitotic figures identical to thos...
T36816 S-trityl-L-Cysteine STLC Kinesin
S-trityl-L-Cysteine is a non-natural amino acid and an inhibitor of Eg5, also known as KSP and Kif11, a mitotic kinesin necessary for mitotic spindle formation. S-trityl-L-Cysteine inhibits the ATPase activity of Eg5 in ...
T28694 SB-743921 free base SB743921,SB-921,SB921,SB-743921,GSK-743921,GSK-921
SB-743921, a kinesin spindle protein (KSP) inhibitor, is used potentially for the treatment of non-Hodgkin's lymphoma (NHL).
T10373 (R)-Filanesib (R)-ARRY-520 Others
(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).
T81871 Mal-PEG8-Val-Ala-PAB-SB-743921
Compound D7, also known as Mal-PEG8-Val-Ala-PAB-SB-743921, is a drug-linker conjugate for antibody-drug conjugates (ADC). It comprises the KSP inhibitor SB-743921 connected through a linker and is utilized in the synthes...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05473 KSP37/FGFBP2 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
TMPY-01763 Cadherin 16/CDH16 Protein, Human, Recombinant (His) Human HEK293
KSP-Cadherin/Cadherin-16 is a member of the cadherin superfamily, calcium-dependent, membrane-associated glycoproteins. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane regio...
TargetMol