IKE

Imidazole ketone erastin (IKE) is an ferroptosis inducer with inhibitory effects on system Xc-cystine/glutamate transporter proteins. Imidazole ketone erastin has antitumor activity and induces glutathione depletion and lipid peroxidation.

Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of end

Aspartyl-alanyl-diketopiperazine (DA-DKP) is a known immunomodulatory molecule derived from the N terminus of human albumin.

Aspartyl-alanyl-diketopiperazine acetate (DA-DKP) (DA-DKP) can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy.

Phe-Met-Arg-Phe Like Peptide acetate (Pqdpflrfamide acetate) is a FMRF-like peptide from visceral and somatic muscles of the snail Helix aspersa. FMRF (Phe-Met-Arg-Phe) is a neuropeptide peptide consisting of 4 amino acid residues.

Dihydroyashabushiketol is a useful organic compound for research related to life sciences. The catalog number is T125228 and the CAS number is 24192-01-6.

Yashabushiketol is a useful organic compound for research related to life sciences. The catalog number is T125229 and the CAS number is 24192-00-5.

Toll-like receptor modulator is a TLR7/8 modulator that regulates immune function.

Diketone-PEG11-Diketone is a polyethylene glycol (PEG)-based linker utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Diketone-PEG11-PFP ester serves as a PEG-based PROTAC linker for PROTAC synthesis[1].

Diketone-PEG12-Biotin is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker promotes selective protein degradation by exploiting the ubiquitin-proteasome system within cells.

Diketone-PEG12-DBCO is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Diketone-PEG4-Biotin is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Diketone-PEG4-PFP ester is a polyethylene glycol (PEG) derivative used as a PROTAC linker in the construction of proteolysis-targeting chimeras (PROTACs) [1].

Dikegulac (Diprogulic acid) serves as a precursor in the synthesis of vitamin C and functions as a plant growth regulator primarily for hedges. It differentially targets and kills terminal apices, while selectively inhibiting fundamental metabolic processes in dividing cells without affecting stationary cells.

biKEAP1 (compound 3) is an inhibitor that targets the KEAP1 dimer. By binding to cellular KEAP1 dimers, biKEAP1 releases the NRF2 protein that is sequestered by KEAP1, leading to the immediate activation of NRF2. This compound also promotes the nuclear translocation of NRF2 and directly inhibits the transcription of pro-inflammatory cytokines. biKEAP1 has demonstrated the ability to alleviate acute inflammation and reduce inflammatory damage in acute inflammation models.

Piketoprofen (Calmatel) is a topical nonsteroidal anti-inflammatory agent.

Lisinopril R,S,S-diketopiperazine is a bioactive chemical.

Prolyldiketopiperazine B is a proline-based diketopiperazine.

Pyroglutamylglutamine diketopiperazine is a bioactive chemical.

Anti-SARS-CoV-2 Spike mAb (CR3022) is a human monoclonal IgG1 antibody produced from CHO cells, which specifically targets the S1 domain of the Spike protein in both SARS-CoV and SARS-CoV-2.

Anti-Spike-RBD mAb is a CHO cell-derived human monoclonal IgG1 antibody that potentially treats SARS-CoV-2 by blocking the interaction between the spike protein and ACE2[1].

The Anti-Spike-RBD Single Domain mAb is a monoclonal antibody derived from CHO cells in Alpaca. It is composed of VHH-huFc and exhibits a strong affinity for the SARS-CoV-2 RBD. [1]

6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2. It was shown to enhance intracellular cAMP and cholesterol catabolism in bovine arterial smooth muscle cells.