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Search Results for " cdk2-in-3 "

10

Compounds

Cat No. Product Name Synonyms Targets
T36933 Cdk2 Inhibitor II Cdk2 Inhibitor II,CDK2-IN-3 CDK
Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.
T35555 GSK-3/CDK5/CDK2-IN-1 GSK-3/CDK5/CDK2-IN-1
GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].
T79728 EGFR/CDK2-IN-3 EGFR
EGFR/CDK2-IN-3 (compound 4b) serves as a dual inhibitor targeting both EGFR and CDK-2, exhibiting IC50 values of 71.7 nM and 113.7 nM, respectively. It prompts apoptosis in MCF-7 cells and halts the cell cycle in the S p...
T77341 GSK-3 inhibitor 4 GSK-3 , CDK
GSK-3 inhibitor 4 is an orally active and brain-permeable triple inhibitor of GSK-3, CDK2 and CDK5 with inhibitory effects on GSK-3β, GSK-3α, CDK2 and CDK5, with IC50 values of 0.56 nM, 0.45 nM, 0.47 μM, 0.68 μM, respect...
T6S1487 Ginsenoside Rg5 NF-κB , COX , IGF-1R
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ...
T14136 AG-024322 CDK
AG-024322 is a potent ATP-competitive inhibitor of pan-CDK against cell cycle kinases CDK1, CDK2, and CDK4(Ki values in the 1-3 nM range)
T63933 CDK1-IN-3
CDK1-IN-3 (8g) is a selective CDK1 inhibitor that acts on CDK1 (IC50: 36.8 nM), CDK2 (IC50: 305.17 nM) and CDK5 (IC50: 369.37 nM). CDK1-IN-3 can affect the cell cycle and thus inhibit the growth of cancer cells and can b...
T61362 CDK5-IN-3
CDK5-IN-3 (compound 11) is a highly potent and selective inhibitor of CDK5, demonstrating significant inhibition with IC50 values of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. This compound holds promise ...
T40546 3-Methylthienyl-carbonyl-JNJ-7706621
3-Methylthienyl-carbonyl-JNJ-7706621 is a highly potent and selective inhibitor of cyclin-dependent kinase (CDK). It exhibits impressive IC50 values of 6.4 nM and 2 nM for CDK1/cyclin B and CDK2/cyclin A, respectively. A...
T60583 CDK1/2/4-IN-1
CDK1/2/4-IN-1 (compound 3a) is a potent inhibitor of CDK with IC 50 values of 1.47, 0.78 and 0.87 μM for CDK1, CDK2 and CDK4, respectively. CDK1/2/4-IN-1 can be used in cancer research. CDK1/2/4-IN-1 arrests cell cycle a...
TargetMol