Biotin-PEG-azide (MW 2000)

Biotin-PEG-azide (MW 2000) is a biotinylated polyethylene glycol (PEG) compound featuring an azide group. Biotin serves as an enzyme cofactor suitable for protein labeling. PEG, noted for its hydrophilicity and water solubility, exhibits low toxicity. The azide functionality is a reasonably effective leaving group that participates in copper-catalyzed reactions with alkynes, enhancing the binding efficiency to biotin's targets.

Biotin-PEG-Biotin (MW 20000) is a bifunctional PEG derivative with biotin labels at each terminal end. Biotin facilitates protein labeling as an enzyme co-factor, while the hydrophilic and low-toxicity nature of PEG imparts water solubility to the compound.

Biotin-PEG-Alk (MW 2000) is a biotin-labeled polyethylene glycol (PEG) derivative with an alkyne group for click chemistry applications. This compound efficiently binds to biotin targets via the alkyne moiety, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAC) and enhancing biotin-avidin interaction assays in bioconjugation processes like protein labeling. The hydrophilic nature of PEG ensures solubility in aqueous environments and minimal toxicity.