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Apelin-36(rat, mouse) TFA

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Apelin-36(rat, mouse) TFA
T75784
Apelin-36(rat, mouse) TFA, an endogenous agonist for the orphan G protein-coupled receptor APJ, exhibits a strong affinity for APJ receptors with an IC 50 of 5.4 nM and effectively inhibits cAMP production with an EC 50 of 0.52 nM. Moreover, it obstructs the invasion of certain HIV-1 and HIV-2 strains into NP-2 CD4 cells that express the APJ receptor [1] [2].
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