Amiodarone hydrochloride

Amiodarone hydrochloride is an anti-anginal agent and a class III antiarrhythmic drug that inhibits potassium channels (including wild-type hERG channels and their tail currents, with an IC₅₀ of approximately 45 nM) as well as voltage-gated sodium channels. This leads to prolonged action potential duration in ventricular and atrial myocytes, resulting in reduced heart rate and vascular resistance. It activates ERK1/2 and p38 MAPK signaling pathways in fibroblasts, promoting cell proliferation and myofibroblast differentiation. Amiodarone hydrochloride is widely used in the study of supraventricular and ventricular arrhythmias and can also be used to establish pulmonary fibrosis animal models.

Di-N-desethyl Amiodarone hydrochloride, a metabolite of Amiodarone, functions as a potent inhibitor of the respiratory chain [1].

Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride), formed by the CYP3A isozyme, is the main active metabolite of amiodarone, an antiarrhythmic drug that inhibits ATP-sensitive potassium channels with an IC50 of 19.1 μM.

Amiodarone hydrochloride (Standard) is a reference standard for research and analysis in studies involving Amiodarone hydrochloride. Amiodarone hydrochloride is an anti-anginal agent and a class III antiarrhythmic drug that inhibits potassium channels (including wild-type hERG channels and their tail currents, with an IC₅₀ of approximately 45 nM) as well as voltage-gated sodium channels. This leads to prolonged action potential duration in ventricular and atrial myocytes, resulting in reduced heart rate and vascular resistance. It activates ERK1/2 and p38 MAPK signaling pathways in fibroblasts, promoting cell proliferation and myofibroblast differentiation. Amiodarone hydrochloride is widely used in the study of supraventricular and ventricular arrhythmias and can also be used to establish pulmonary fibrosis animal models.

Desethylamiodarone hydrochloride (Standard) is a reference standard for research and analysis in studies involving Desethylamiodarone hydrochloride. Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride), formed by the CYP3A isozyme, is the main active metabolite of amiodarone, an antiarrhythmic drug that inhibits ATP-sensitive potassium channels with an IC50 of 19.1 μM.

Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.

Amiodarone-d4 HCl is a deuterated compound of Amiodarone HCl. Amiodarone HCl has a CAS number of 19774-82-4. Amiodarone hydrochloride is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.

Amiodarone-d10 Hydrochloride is a deuterated compound of Amiodarone Hydrochloride. Amiodarone Hydrochloride has a CAS number of 19774-82-4. Amiodarone hydrochloride is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.

Dronedarone-d6 HCl is a deuterated compound of Dronedarone HCl. Dronedarone HCl has a CAS number of 141625-93-6. Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.

Amiodarone-D4 Hcl (Standard) is a reference standard of Amiodarone-D4 Hcl intended for quantitative analysis, quality control, and related biochemical research applications. Amiodarone-d4 HCl is a deuterated compound of Amiodarone HCl. Amiodarone HCl has a CAS number of 19774-82-4. Amiodarone hydrochloride is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.