ad2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T63601	PAD2-IN-1 hydrochloride
	PAD2-IN-1 hydrochloride is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor with superior selectivity for PAD2 over PAD4 (95-fold) and PAD3 (79-fold), and is a benzimidazole-based derivative.
T69351	AD2765
	AD2765, also known as AD 2845 and Sphingosylphosphoryl choline, is a novel thiourea derivative of sphingomyelin that inhibits sphingomyelin hydrolysis and synthesis, increases ceramide, and leads to cell death.
T13218	TT-OAD2		Others
	TT-OAD2 is a non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor (EC50: 5 nM), with the potential for diabetes treatment.		Others
T39515	PAD2-IN-1	PAD2-IN-1
	PAD2-IN-1, a benzimidazole-based derivative, is an efficacious and specific inhibitor of protein arginine deiminase 2 (PAD2). Demonstrating remarkable selectivity, PAD2-IN-1 exhibits a 95-fold higher affinity for PAD2 in...
T11406	TT-OAD2 free base		Others
	TT-OAD2 free base has the potential for diabetes treatment. TT-OAD2 free base is a non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist with an EC50 of 5 nM.		Others

Compounds

PAD2-IN-1 hydrochloride

T63601

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-05297	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPY-05528	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated	Human	E. coli
	Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPH-03192	NAD2 Protein, Psoroptes ovis, Recombinant (His)	Psoroptes ovis	in vitro E. coli expression system
	NAD2 Protein, Psoroptes ovis, Recombinant (His) is expressed in in vitro E. coli expression system.
TMPH-01699	SMAD2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in t...
TMPH-02300	RAD23A Protein, Human, Recombinant (His)	Human	E. coli
	Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chain...
TMPY-02238	MAD2L1 Protein, Human, Recombinant (His)	Human	E. coli
	Mitotic spindle assembly checkpoint protein MAD2A, also known as HsMAD2, Mitotic arrest deficient 2-like protein 1, MAD2-like protein 1, MAD2L1, and MAD2, is a nucleus and cytoplasm protein that belongs to the MAD2 famil...
TMPH-02225	TEAD2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is...
TMPY-03291	SMAD2 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	SMAD2 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD...