5-fluorouridine

5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compounds comprising a pyrimidine base attached to a sugar. 5-fluorouridine is known to target uridine phosphorylase. FUrd is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs.

5-Fluorouridine 5'-phosphate acts as an ODCase (uridine 5'-monophosphate decarboxylase) inhibitor, exhibiting a Ki value of 98 µM for human ODCase and 645 µM for Methanococcus jannaschii ODCase. This compound also shows inhibitory activity on leukemia and lymphoma cell lines, making it useful for cancer research studies.

5-Fluorouridine 5'-O-β-D-galactopyranoside (also known as 5'-O-β-D-galactosyl-5-fluorouridine) is a prodrug of 5-Fluorouridine. It can be enzymatically converted by β-D-galactosidase into 5-Fluorouridine, a highly effective antineoplastic agent.

5'(R)-C-Methyl-5-fluorouridine, a uridine analogue, potentially exhibits antiepileptic properties. Its analogues play a crucial role in researching anticonvulsant and anxiolytic effects and are essential in developing new antihypertensive agents [1].

3'-Deoxy-3'-fluoro-5-fluorouridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 5-modified pyrimidine nucleoside, 3'-Modified nucleoside.

Nucleoside Derivatives - Azido-nucleosides, 3'-Modified nucleosides, 5-Modified pyrimidine nucleosides; Fluoro-modified nucleosides

Nucleoside Derivatives - 5'-Modified nucleosides, 5-Modified pyrimidine nucleosides, Fluoro-modified nucleosides

3'-Deoxy-3'-a-C-methyl-5-fluorouridine is a Nucleoside Derivative - 3'-Modified nucleoside, 5-Modified pyrimidine nucleoside, Fluoro-modified nucleoside.

Nucleoside Derivatives - Amino-nucleosides, 3'-Modified nucleosides, Fluoro-modified nucleosides, 5-Modified pyrimidine nucleosides

Nucleoside Derivatives - 3'-Deoxy nucleosides, 5-Modified pyrimidine nucleosides, Fluoro-modified nucleosides

2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-fluorouridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 5-modified pyrimidine nucleoside, 3'-Modified nucleoside.

2'-Deoxy-5-Fluorouridine 5'-phosphate triethyl ammonium salt is a valuable organic compound for life sciences research (catalog number TNU1203, CAS number 134-46-3).

Nucleoside Derivatives - Halo-nucleoside; 5-modified nucleosides; 2'-Modified nucleosides; Fluoro-modified nucleosides

Nucleoside Derivatives - 3'-Modified nucleosides, Fluoro-modified nucleosides, 5-Modified pyrimidine nucleosides

2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue derived from 5'-O-DMTr-5-FUDR, exhibits strong anti-yellow fever (YFV) activity.

2'-Deoxy-2'-fluorouridine 5'-monophosphate triethyl ammonium, a purine nucleoside analog, demonstrates significant antitumor effects against indolent lymphoid malignancies by primarily inhibiting DNA synthesis and inducing apoptosis [1].

5-Iodo-3'-deoxy-3'-fluorouridine is a Nucleoside, fluoro-modified nucleoside, halo-nucleoside.

Nucleoside Derivatives –Fluoro-modified nucleosides; 5'-Modified nucleosides, 2'-Modified nucleosides

Nucleoside Derivatives - Azido-nucleosides, 5'-Modified nucleosides, 2'-Modified nucleosides, Fluoro-modified nucleosides

3'-Deoxy-5'-O-(4,4'-Dimethoxytrityl)-3'-fluorouridine, with catalog number TNU1423 and CAS number 129015-60-7, is a valuable organic compound for life sciences research.

3'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-3'-fluorouridine-2'-CED-phosphoramidite is a Nucleoside Phosphoramidite.

Halo-nucleoside; Fluoro-modified nucleoside

Nucleoside Phosphates;

5-Fluorouracil (5-FU) is a uracil analog and inhibitor of DNA synthesis, exhibiting antitumor activity by affecting pyrimidine synthesis through thymidylate synthase inhibition; it induces apoptosis and autophagy.