5-fluorouridine

5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compounds comprising a pyrimidine base attached to a sugar. 5-fluorouridine is known to target uridine phosphorylase. FUrd is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs.

5-Fluorouridine 5'-O-β-D-galactopyranoside (also known as 5'-O-β-D-galactosyl-5-fluorouridine) is a prodrug of 5-Fluorouridine. It can be enzymatically converted by β-D-galactosidase into 5-Fluorouridine, a highly effective antineoplastic agent.

5-Fluorouridine 5'-phosphate acts as an ODCase (uridine 5'-monophosphate decarboxylase) inhibitor, exhibiting a Ki value of 98 µM for human ODCase and 645 µM for Methanococcus jannaschii ODCase. This compound also shows inhibitory activity on leukemia and lymphoma cell lines, making it useful for cancer research studies.

5'(R)-C-Methyl-5-fluorouridine, a uridine analogue, potentially exhibits antiepileptic properties. Its analogues play a crucial role in researching anticonvulsant and anxiolytic effects and are essential in developing new antihypertensive agents [1].

3'-Deoxy-3'-fluoro-5-fluorouridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 5-modified pyrimidine nucleoside, 3'-Modified nucleoside.

3'-Deoxy-3'-a-C-methyl-5-fluorouridine is a Nucleoside Derivative - 3'-Modified nucleoside, 5-Modified pyrimidine nucleoside, Fluoro-modified nucleoside.

2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-fluorouridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 5-modified pyrimidine nucleoside, 3'-Modified nucleoside.

2'-Deoxy-5-Fluorouridine 5'-phosphate triethyl ammonium salt is a valuable organic compound for life sciences research (catalog number TNU1203, CAS number 134-46-3).

Nucleoside Derivatives - Azido-nucleosides, 3'-Modified nucleosides, 5-Modified pyrimidine nucleosides; Fluoro-modified nucleosides

Nucleoside Derivatives - 5'-Modified nucleosides, 5-Modified pyrimidine nucleosides, Fluoro-modified nucleosides

Nucleoside Derivatives - Amino-nucleosides, 3'-Modified nucleosides, Fluoro-modified nucleosides, 5-Modified pyrimidine nucleosides

Nucleoside Derivatives - 3'-Deoxy nucleosides, 5-Modified pyrimidine nucleosides, Fluoro-modified nucleosides

Nucleoside Derivatives - Halo-nucleoside; 5-modified nucleosides; 2'-Modified nucleosides; Fluoro-modified nucleosides

Nucleoside Derivatives - 3'-Modified nucleosides, Fluoro-modified nucleosides, 5-Modified pyrimidine nucleosides

5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluoro-uridine is a Nucleoside Derivative - Didehydro-nucleoside; Fluoro-modified nucleoside.

Nucleoside Derivatives - 2',3'-Dideoxy-nucleoside; Fluoro-modified nucleoside

2',3'-Dideoxy-2',3'-didehydro-5-fluoro-uridine is a Nucleoside Derivative - Didehydro-nucleoside; Fluoro-modified nucleoside.

Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.

Potassium oxonate is a uricase inhibitor that suppresses the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate and is commonly used to establish hyperuricemia models.

2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue derived from 5'-O-DMTr-5-FUDR, exhibits strong anti-yellow fever (YFV) activity.

2'-Deoxy-2'-fluorouridine 5'-monophosphate triethyl ammonium, a purine nucleoside analog, demonstrates significant antitumor effects against indolent lymphoid malignancies by primarily inhibiting DNA synthesis and inducing apoptosis [1].

Capecitabine-d11 is a deuterated compound of Capecitabine. Capecitabine has a CAS number of 154361-50-9. Capecitabine is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.

Capecitabine (Standard) is a reference standard for research and analysis in studies involving Capecitabine. Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.

5-Iodo-3'-deoxy-3'-fluorouridine is a Nucleoside, fluoro-modified nucleoside, halo-nucleoside.