12 methyl myristic acid methyl ester

12-methyl Myristic acid methyl ester is a methylated fatty acid methyl ester that has been found in vermicomposts of cattle manure, carica papaya leaves, and cuticular wax of K. africana. It is a volatile compound in lipid-lowering granulated tea. Levels of 12-methyl myristic acid methyl ester are decreased in T. cruzi treated with nifurtimox compared to non-treated controls.

C12-200 is a benchmark ionizable cationic lipidoid along with helper lipids and can be used in the delivery of mRNA.

Polyethylene glycol 12-hydroxystearate (Solutol HS-15) is a permeability enhancer.

Sulfobetaine-12 (Zwittergent 3-12 Detergent) is a zwitterionic surfactant, dispersant and emulsifier commonly used in industry.

Collagenase, Type VIII, has the capability to hydrolyze Type VIII collagen, and may be utilized in the study of atherosclerosis development. Type VIII collagen serves as a regulator of endothelial cell differentiation and angiogenesis, acts as a substrate for the adhesion and migration of cells such as smooth muscle cells, and may accumulate in atherosclerosis. Following the activation by endotoxins, the expression of Collagenase, Type VIII can reduce the production of Type VIII collagen, potentially inhibiting the progression of atherosclerosis.

M-PEG12-Mal is a PEG derivative containing a maleimide group. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group could form a covalent bond with a thiol group , enabling the further connection of biomolecule with a thiol

Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. bovisbiofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron.2It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively).3Nocardamine also induces morphological changes in BM-N4 insect cells.4 1.Lopez, J.A.V., Nogawa, T., Futamura, Y., et al.Nocardamin glucuronide, a new member of the ferrioxamine siderophores isolated from the ascamycin-producing strain Streptomyces sp. 80H647J. Antibiot. (Tokyo)72(12)991-995(2019) 2.Ishida, S., Arai, M., Niikawa, H., et al.Inhibitory effect of cyclic trihydroxamate siderophore, desferrioxamine E, on the biofilm formation of Mycobacterium speciesBiol. Pharm. Bull.34(6)917-920(2011) 3.Kalinovskaya, N.I., Romaneko, L.A., Irisawa, T., et al.Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activityMicrobiol. Res.166(8)654-661(2011) 4.Matsubara, K., Sakuda, S., Tanaka, M., et al.Morphological changes in insect BM-N4 cells induced by nocardamineBiosci. Biotechnol. Biochem.62(10)2049-2051(1998)

D-threo Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and L-erythro sphinganine (d18:0) . It induces autophagy in HCT116 cells when used at a concentration of 12 μM. D-threo Sphinganine (d18:0) is metabolized via sphinganine N-acyltransferase and sphinganine kinase in vivo in rat liver.

n-Heptyl β-D-glucopyranoside is a useful organic compound for research related to life sciences. The catalog number is T66686 and the CAS number is 78617-12-6.

Lauroyl coenzyme A lithium salt is a type of coenzyme A that acts as an acyl carrier, specifically acetyl-CoA. Lauryl-CoA (C12-CoA) is a long-chain (C-12) saturated fatty acyl-CoA involved in lipid metabolism, lipid biosynthesis, and fatty acid transport. It serves as a substrate for the FAM34A protein and is a product of firefly luciferase.

12:0 EPC chloride, a cationic phospholipid, is utilized for drug delivery [1].

Diamino lipid DAL4 is novel lipid nanoparticles (LNPs) encapsulated with mRNAs encoding cytokines including IL-12 , IL-27 and GM-CSF . Diamino lipid DAL4 delivers mRNA to tumor cells to exert anti-tumor activity [1] .

Trisodium phosphate dodecahydrate serves as a corrosion inhibitor for iron in 0.1 M NaClO4 solutions, effective under both aerated and deaerated conditions. Additionally, it acts as an excipient in pharmaceutical formulations, functioning primarily as a pH regulator and buffer. These excipients, also known as pharmaceutical auxiliaries, are substances utilized in the pharmaceutical manufacturing process besides the active pharmaceutical ingredients. They are crucial for enhancing the stability, solubility, and processability of pharmaceutical products. Moreover, pharmaceutical excipients play a significant role in influencing the absorption, distribution, metabolism, and elimination (ADME) of co-administered drugs, thereby affecting their efficacy and safety [1] [2].

9(Z),12(Z),15(Z)-Heneicosatrienoic acid is a reagent used in biochemical reactions.

N-12:0-1-Deoxysphinganine is a reagent used in biochemical reactions.

12:0 Diether PC is a reagent used in biochemical reactions.

18:1-12:0 Biotin PE (1-Oleoyl-2-(12-biotinyl(aminododecanoyl))-sn-glycero-3-phosphoethanolamine) is suitable for liposome preparation.

16:0-12 Doxyl PC (1-Palmitoyl-2-stearoyl-(12-doxyl)-sn-glycero-3-phosphocholine) functions as a fluorescence quencher, with the nitroxide group situated downstream on the sn-2 chain. It exhibits enhanced fluorescence quenching for fluorophores embedded within the bilayer hydrocarbons.

Methyl 12-hydroxystearate is an organic compound categorized as an ester, formed through the reaction of methanol with 12-hydroxystearic acid. Additionally, [Methyl 12-hydroxystearate] is used in industrial settings as a lubricant and surfactant.

(E)-12-hydroxyoctadec-9-enoic acid sodium is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Methyl 12-aminododecanoate hydrochloride is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Monophosphoryl Lipid A-12 is a reagent used in biochemical reactions.

n-Tridecyl-β-D-Maltopyranoside is a useful organic compound for research related to life sciences. The catalog number is TF0087 and the CAS number is 93911-12-7.

DPPS (12-Dipalmitoyl-sn-glycero-3-PS sodium salt) is an anionic diacyl-phospholipid, a form of phosphatidylserine (PS), which is a negatively charged phospholipid located in the lobules of cell membranes. DPPS are used to make cationic vesicles and liposomes.