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Results for "
(e/z)-gsk 5182
" in TargetMol Product Catalog- Inhibitors & Agonists1
(E/Z)-GSK5182
GSK5182(Z E)
T77092699724-40-6
(E Z)-GSK5182 (GSK5182(Z E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating potency with an IC50 of 79 nM. Additionally, GSK5182 is known to induce the generation of reactive oxygen species (ROS) in hepatocellular carcinoma.
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