Roemerine ((-)-Roemerine) is a porphyrin alkaloid from Senegalese lychee with antifungal and anticancer activity that prevents berberine efflux through inhibition of Bmr. Roemerine increases cell membrane permeability in a concentration-dependent manner and has been used in studies of fungal infections and prostate cancer.

Lotusine, a pure alkaloid extracted from the Nelumbo nucifera Gaertn., affects action potentials in the myocardium and slow inward current in cardiac Purkinje fibers.

Dehydronuciferine, isolated from the leaves of Nelumbo nucifera Gaertn, exhibits acetylcholinesterase inhibition with an IC50 of 25 µg/mL.

1,2-Dimethylnaphthalene is a specific dimethylnaphthalene isomer carrying methyl substituents at the 1 and 2 positions on the naphthalene ring system, and this polycyclic aromatic hydrocarbon has been reported as a natural constituent in several plant species including Phaseolus vulgaris, Nelumbo lutea, and Magnolia liliiflora.

2-Hydroxy-1-Methoxyaporphine can inhibit CYP2D6 activity, it also increase the glucose consumption significantly as rosiglitazone.

N-Methylcoclaurine shows binding affinities for the ĸ opioid receptor with the equilibrium dissociation constant (Ki) value of 0.9 ± 0.1 uM. N-methylcoclaurine also shows promising butyrylcholinesterase inhibition activities, with the IC50 value of 1

N-norarmepavine shows significant cytotoxic activities against HL-60 carcinoma cell line with inhibitory ratios of 51.43% at concentration of 1 x 10(-5) M. Norarmepavine shows inhibition against Trypanosoma cruzi. D-(+)- N-norarmepavine exhibits significa