Periplogenin 3-[O-β-glucopyranosyl-(1→4)-β-sarmentopyranoside] (Periplogenin 3-[O-beta-glucopyranosyl-(1->4)-beta-sarmentopyranoside]) is a carmenolide extracted from Periploca sepium.

Periplocymarin is a cardiac glycoside with anticancer potential isolated from Periploca sepium and Periploca graeca.

Sepiumol A is a polyphenolic compound isolated from the root bark of Periploca sepium, which has significant antifungal activity and inhibits methicillin-resistant Staphylococcus aureus, and can be used in the study of fungal infections.

Perisesaccharide C is a natural product

Periplocoside N possesses insecticidal activities against the red imported fire ant.

Perisesaccharide B is a natural product

Beta-Amyrin palmitate may release norepinephrine from newly synthesized pools, and thus, it may activate noradrenergic activity. Beta-Amyrin palmitate, like mianserin and imipramine, reduces the duration of immobility of mice significantly in a dose-depen

Periplocoside M possesses observably antitumor activity against SMMC-7721( IC 50=12.9 ng L),Hela( IC 50=8.63 ng L) and MCF-7( IC 50=18.5 ng L) cancer cell lines.

Acetyl Perisesaccharide C is a natural product